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Introduction

Per‑ and polyfluoroalkyl substances (PFAS) are persistent environmental contaminants that can accumulate in animal‑derived foods, creating growing regulatory and public health concerns. Traditional PFAS testing methods often rely on time‑consuming solid‑phase extraction (SPE) and extensive cleanup to manage complex tissue matrices.

This application note demonstrates a simplified, high‑throughput Blend & Inject LC‑MS/MS workflow using the PerkinElmer QSight® 500 LC‑MS/MS system for reliable PFAS quantification in animal‑derived food products while meeting stringent EU and EPA regulatory requirements.

Key Highlights:

  • Faster PFAS testing with a direct Blend & Inject workflow, no SPE required.
  • Accurate results in complex tissues using matrix‑matched calibration and internal standards.
  • EU‑compliant sensitivity and throughput with LOQs down to 0.025 µg/kg on QSight® 500 LC‑MS/MS.
 

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