PerkinElmer

Organic Impurities

Pharmaceutical laboratories summarise actual and potential impurities that are most likely to arise during the synthesis, purification, and storage of the drug substance and excipients. The finished dosage forms summarize the degradation products observed during manufacture and stability studies of the drug product, including impurities arising from the interaction with excipients and/or the immediate container closure system.

All the studies conducted to characterize any impurity at a level greater than the identification threshold – in any batch manufactured by the proposed commercial process – should be identified. In addition, any degradation product observed in stability studies at recommended storage conditions at a level greater than the identification threshold should be identified to guarantee the safety of medicines.

We provide the tools and processes you need to take control of your organic impurities testing for drug substances, drug products, and excipients.

UHPLC

Ultra-high performance means the highest resolution, highest sensitivity and fastest analysis to detect impurities in samples. The Flexar FX-20 is the ultimate in UHPLC with maximum throughput and minimum stress for you. Getting more sample information in less time lets you be more productive. Just what you want.

  • Dual-reciprocating piston 18,000 psi pump provides as much as 10 times, if not more, improvement in productivity
  • UV/Vis and PDA detectors offer fast, sensitive performance for a wide range of applications
  • Integrated piston wash function keeps pump pistons clean, even with buffers
  • Synchronized injection with piston position for ultimate retention time precision
  • View pump pressure profiles real-time with Chromera® CDS
  • Pulse dampener-less design allows for increased productivity with less recovery time between runs
  • Dual binary solvent selection adds more solvent choices to support your applications

Learn More

Flexar HPLC

The need for high performance and reliability are a given for QC labs performing assays to determine the strength and content of drug substances. Our proven, rugged, and reliable Flexar HPLC system is the perfect choice when you need fast cycle times, reproducibility, and low carryover. With its elegant streamlined interface,the Flexar HPLC is easy to use and simplifies your day-to-day processes so you can focus on your applications.

  • Integrated LC tube management for streamlined chromatography
  • UV/Vis and PDA detectors offer fast, sensitive performance for a wide range of applications
  • Hidden plug-and-play drainage automatically interconnects with components added to system
  • Convenient solvent manager with integrated degasser and software communication link
  • Built on rugged and reliable LC technology for maximum uptime and low cost of ownership

Learn More

Clarus 590 GC

If your lab performs routine impurities testing analyses, you need a flexible, rugged GC instrument that can meet your testing requirements. The Clarus® 590 gas chromatograph is a fully automated GC system that delivers capabilities that enable high performance, flexibility, and stability. Along with proven strengths of our GC platform, the Clarus 590 GC features a new high-performance capillary injector with decreased reactivity, and autosampler technology that delivers multiple options for liquid injection, headspace, and SPME in one system.

  • A wide range of injectors, including programmable and on-column
  • All common detectors, including ECD, TCD, and FPD
  • Multilanguage touchscreen operation
  • Microchannel (Swafer) technology expands analytical capabilities with complete independence of the column from injectors or detectors
  • Capillary injector to ensure optimal recoveries and increased sensitivity
  • Programmable pneumatic control (PPC) for greater system stability, even with extreme changes in temperature

Learn More

Clarus 690 GC

When the highest levels of throughput are critical to your operations, choose the Clarus® 690 gas chromatograph. Its patented high-performance oven delivers the fastest heat-up and cool-down of any oven in the business, and that means shorter injection-to-injection times, and the ability to run more samples per day. Plus, the oven’s twin-wall design with concentric air exhaust provides exceptional cooling to near-ambient temperatures without resorting to liquid cryogen – critical for analysis of organic compounds.

  • Fastest combined heat-up and cool-down rate of any conventional over to enhance productivity, efficiency and throughput.
  • A wide range of injectors, including programmable and on-column
  • All common detectors, including ECD, TCD, and FPD
  • Multilanguage touchscreen operation
  • Microchannel (Swafer) technology expands analytical capabilities with complete independence of the column from injectors or detectors
  • Capillary injector to ensure optimal recoveries and increased sensitivity
  • Programmable pneumatic control (PPC) for greater system stability, even with extreme changes in temperature

Learn More

Consumables

Our accessories, consumables, methods, and application support meet the most demanding requirements and are the preferred choice in thousands of laboratories globally.

We invest heavily in testing and validating our complete portfolio of solutions to ensure that you receive accurate, repeatable results – on-time, every time – throughout the lifetime of your instrument. We also offer a complete portfolio of specialized consumables that deliver reliable performance, control operating costs, and maximize the uptime of your instrument.

Learn More

Services

The OneSource® UOQ program provides an instrumentation qualification program for maximum productivity and ongoing regulatory compliance capability. The program encompasses pharmacopeial (USP, EP, and JP) compliance with a design and approach that streamlines documentation across all major models of laboratory instruments, regardless of manufacturer.

OneSource Compliance Services ensures the highest levels of compliance with international regulations and guidelines. UOQ enables a seamless, cross-platform approach to a contemporaneous and automated documentation process, letting you gain immediate access to raw data from computer or database, for increased scientific productivity.

Learn More

Questions? We're here to help