Pesticide Analysis
With residual levels strictly regulated for human health and safety, short analytical turnaround times are critical to providing the necessary information required to rapidly detect the presence of pesticides in food. For rapid and highly sensitive screening of food matrices to detect the presence of pesticides residues, our chromatographic technologies are trusted throughout the industry. Our QSight™ Pesticide Analyzer, built to run hundreds of pesticides in one run with the utmost sensitivity and efficiency, it is the only instrument that provides 15% higher throughput than conventional systems.
Pesticide Residues and Illegal Additives in Wine
Both pesticides and illegal additives, if present in significant levels in wine, can pose health risk to consumers. In this study, a simple and sensitive LC-MS/MS method has been developed and applied for the determination of both pesticides and pigments in a single analytical run.
Efficient LC/MS/MS Method for Testing Hemp Samples for Pesticide Residues
Agricultural growing of hemp products for the purposes of cannabidiol (CBD) extraction was legalized in the United States with the passing of the Agricultural Improvement Act of 2018. Since the act passed, heightened concern over the use of pesticides in hemp production has been appreciated. However, no federal guidance is currently available in the United States to standardize analytical methods for the detection and quantification of pesticide residues in hemp products. In this application note, a robust and efficient single-run LC/MS/MS method for the determination of 66 pesticides, including hydrophobic and chlorinated pesticides typically analyzed by GC/MS/MS, is presented. Utilizing a PerkinElmer QSight® 420 UHPLC with MS/MS detector and dual ESI and APCI sources, excellent recoveries in the range of 70-120% were achieved. The application note also outlines participation in an Emerald Scientific blind proficiency test, with acceptable results for all 66 pesticides.
Pesticide in Grapes by LC-MS/MS
The Grape crop is one of the most important fruit crops consumed in the world. Grapes are consumed both as fresh and as processed products, such as wine, jam, juice, jelly, grape seed extract, raisins, vinegar and grape seed oil. A large variety of pesticides are used in grape production throughout its growing season to control pests and diseases in vineyards and to increase crop yield. Pesticide residue is a major concern for the stakeholders of the grape industry, due to more and more stringent regulations and safety standards in most countries.
Pesticide Residues Analysis by Clarus GC
This Application Note talks about pesticide residues analysis tested by Clarus 690 Gas Chromatograph
"No Dilute” Just Shoot: Robustness of a QSight LC-ESI-MS/MS for Pesticide Residue Analysis in Wine
QSight LC/MS/MS evaluates eliminating sample preparation for trace level pesticide in wine
Direct Analysis of Glyphosate in Wine with No Sample Preparation
Glyphosate is an organophosphate herbicide that is used on crops to kill weeds and grasses. We present a study that involves direct analysis of glyphosate in wine on a mixed mode column with no sample dilution or extraction using a PerkinElmer QSight® 220 triple quadruple mass spectrometer with a patented StayClean™ source, consisting of a hot surface induced desolvation (HSID)™ interface and a Laminar Flow Ion Guide™. Both the HSID and ion guide prevent any contaminants from entering the mass spectrometer, keeping it at its highest performance level and, thereby, maintenance free.
Detection of Fipronil and its Metabolites in Eggs
A recent recall of contaminated eggs in Europe has generated a serious health concern for fipronil poisoning. Fipronil is a highly toxic insecticide and it is used to protect crops. The U.S. EPA has classified fipronil as a group C carcinogen. In this study, we describe a fast and robust analytical method for identifying fipronil and its metabolites with the PerkinElmer QSight® 200 series LC/MS/MS triple quadrupole instrument. The results demonstrate excellent recovery, linearity and reproducibility and superior sensitivity for this method. The three-step sample preparation procedure is quick and easy, and the LC/MS/MS analysis time can be carried out within six minutes with great separation for all analytes.
A Single Cannabis Method to Meet California Pesticide and Mycotoxin Residues Regulatory Requirements
Testing for the levels of pesticide and mycotoxins in cannabis is important to ensure consumer safety and quality control. In this work, the PerkinElmer application development team analyzed all 66 pesticides (including very hydrophobic and chlorinated pesticides typically analyzed by GC-MS/MS) and five mycotoxins spiked in cannabis flower extracts well below the action limits specified by the state of California. A LC-MS/MS instrument was used with ESI and APCI sources and a simple solvent extraction method with excellent recoveries for all analytes in acceptable range of 70-120%.
Meeting Canadian Cannabis Pesticide Residues Regulatory Requirements by LC/MS/MS
Following the 2018 legalization of recreational cannabis usage in Canada, the quality and safety of cannabis products has garnered significant attention. Health Canada has developed a regulatory program mandating pesticide testing on all cannabis products. Under the program, licensed producers (LPs) of cannabis products in Canada are required to send representative samples of products to independent laboratories for pesticide screening and quantification. In this application note, a robust and reliable method for the analysis of 96 pesticides in cannabis flower by LC/MS/MS utilizing both ESI and APCI modes is presented. The method not only offers ultra-low detection limits at or below the Health Canada regulatory levels, but also offers significant efficiency gains over other available methodologies. Utilizing LC/MS/MS with both ESI and APCI modes obviates the need to perform both GC/MS/MS and LC/MS/MS analyses to analyze all 96 regulated pesticides, saving significant time and money for operators.
Analysis of Pesticide Residues in Cannabis Regulated by Oregon State Using LC/MS/MS
Liquid chromatography-tandem mass spectrometry (LC/MS/MS) has become the method of choice for pesticide. The state of Oregon has issued regulatory limits for 59 pesticide residues in both cannabis flower and concentrates, while other states have come up with their own lists of pesticide residues relating to medical marijuana and cannabis testing.
Analysis of Multi-Residue Pesticides in Rice by LC/MS/MS
Liquid chromatography tandem mass spectrometry (LC/MS/MS) has become the method of choice for pesticide analysis due to its high selectivity and sensitivity as well as its suitability for a wide range of compounds in various sample matrices. 0 In this study, a fast, sensitive and selective multi- residue method has been developed for analysis of over 200 pesticides in rice samples by coupling a modified QuEChERS extraction method with LC/MS/MS. Using time-managed- MRM™ in the QSight® triple quadrupole mass spectrometer, the optimum dwell time of multiple MRM transitions can be generated automatically for the targeted analytes. This not only saves time in method development but also improves data quality and analytical performance, as demonstrated in this study by the results of multi- residue pesticide analysis in rice samples.
Analysis of Target Pesticide Residues in Berries with LC/MS/MS Coupled with a QuEChERS Sample Prep
Analysis of target pesticide residues in berries using a unique laminar flow UHPLC-ESI-MS/MS
Novel ESI and APCI LC/MS/MS Method for Testing Cannabis and Hemp Concentrate Samples
The use of cannabis concentrates and CBD products (edibles, topicals, vape products, etc.) has increased in popularity as new regulation has been passed legalizing medicinal and recreational use in a number of states and provinces. Testing to ensure that pesticide and mycotoxin levels in cannabis products are below regulatory levels is critical, however, the cannabis concentrate matrix presents many analytical challenges including higher sample matrix effects and an increased concentration of cannabinoids in the sample. In this application note, an LC/MS/MS method for the analysis of 66 pesticides (including hydrophobic and chlorinated pesticides typically analyzed by GC/MS/MS) and five mycotoxins in a cannabis concentrate matrix is presented. Utilizing a QSight® 420 LC/MS/MS instrument with dual APCI and ESI sources, the analysis yielded excellent recoveries and detection limits below those specified by the state of California cannabis regulations.
Direct Analysis of Glyphosate and Similar Polar Pesticides in Oatmeal by UHPLC-MS/MS
Analysis of glyphosate and similiar polar pesticides in oatmeal using the PerkinElmer QSight LCMSMS.
It is very well known that Black pepper is a complex matrix that requires a proper extraction and clean-up method for interferences. In this study, a fast, sensitive and selective multi-residue method has been developed for analysis of over 136 pesticides in Pepper samples by coupling a modified QuEChERS extraction method with LC/MS/MS. Using time-managed- MRM™ in the QSight™ triple quadrupole mass spectrometer, the optimum dwell time of multiple MRM transitions can be generated automatically for the targeted analytes. This not only saves time in method development but also improves data quality and analytical performance of instrument.
Pesticide Analysis Related Technologies
