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Laboratory Automation Solutions in Cannabis & Hemp

Fully Automated Pesticide Residue Testing Workflow specifically developed for high volume Cannabis & Hemp testing laboratory environments.

Recognizing that Cannabis and hemp testing is challenging due to the diversity of the sample matrix, the lack of published methodologies, and the availability of a complete solution from one partner PerkinElmer has developed a fully automated pesticide testing workflow.

Cannabis Pesticide Workflow

Currently, most laboratories, require multiple sample preparation steps to perform their pesticide residue assay. This workflow is time-consuming, prone to errors due to the human variability, and poorly suited to high volume cannabis and hemp testing labs. To dramatically improve the labs "Turn Around Time" and data quality, PKI has developed a fully automated sample preparation workflow and LC/MSMS analytical solution to meet State and Country cannabis compliance needs.

The fully automated cannabis sample preparation workflow, which includes the ONE Pesticide420™ reagent kit, JANUS® G3 420 Workstation, QSight® 420 LC/MSMS, integrated SimplicityLab420™ software for data management, and cannabis specific SOPs, ensures that only the highest quality of cannabis products reach the consumer.


Advantages of Automated Cannabis & Hemp Testing Solutions

  • A streamlined solution from a single supplier for easy implementation and application support
  • Faster, easier and fully automated sample preparation with micro balance, vortex, and centrifuge ondeck
  • Industry leading analytical and mass spectrometry technology with intuitive cloud-based software

The fully automated pesticide residue workflow helps labs run four to five times faster to increase their productivity, reduce consumable cost with innovative washing program, improve compliance with complete sample traceability with automatic data management across technology platforms and LIMs, and automate cannabis testing lab workflows such as pesticide and mycotoxin residue analysis, potency, and qPCR microbial analysis.

Laboratory Automation Solutions Related Content and Applications

  • Pesticide and Mycotoxin Testing

Pesticide and Mycotoxin Testing

Automated methods for the JANUS® G3 workstations are available for cannabis sample preparation for PerkinElmer’s analytical instruments and testing methods for Pesticides and Mycotoxin Testing.

Novel ESI and APCI LC/MS/MS Method for Testing Cannabis and Hemp Concentrate Samples

The use of cannabis concentrates and CBD products (edibles, topicals, vape products, etc.) has increased in popularity as new regulation has been passed legalizing medicinal and recreational use in a number of states and provinces. Testing to ensure that pesticide and mycotoxin levels in cannabis products are below regulatory levels is critical, however, the cannabis concentrate matrix presents many analytical challenges including higher sample matrix effects and an increased concentration of cannabinoids in the sample. In this application note, an LC/MS/MS method for the analysis of 66 pesticides (including hydrophobic and chlorinated pesticides typically analyzed by GC/MS/MS) and five mycotoxins in a cannabis concentrate matrix is presented. Utilizing a QSight® 420 LC/MS/MS instrument with dual APCI and ESI sources, the analysis yielded excellent recoveries and detection limits below those specified by the state of California cannabis regulations.

Analysis of Pesticide Residues in Cannabis Regulated by Oregon State Using LC/MS/MS

Liquid chromatography-tandem mass spectrometry (LC/MS/MS) has become the method of choice for pesticide. The state of Oregon has issued regulatory limits for 59 pesticide residues in both cannabis flower and concentrates, while other states have come up with their own lists of pesticide residues relating to medical marijuana and cannabis testing.

Efficient LC/MS/MS Method for Testing Hemp Samples for Pesticide Residues

Agricultural growing of hemp products for the purposes of cannabidiol (CBD) extraction was legalized in the United States with the passing of the Agricultural Improvement Act of 2018. Since the act passed, heightened concern over the use of pesticides in hemp production has been appreciated. However, no federal guidance is currently available in the United States to standardize analytical methods for the detection and quantification of pesticide residues in hemp products. In this application note, a robust and efficient single-run LC/MS/MS method for the determination of 66 pesticides, including hydrophobic and chlorinated pesticides typically analyzed by GC/MS/MS, is presented. Utilizing a PerkinElmer QSight® 420 UHPLC with MS/MS detector and dual ESI and APCI sources, excellent recoveries in the range of 70-120% were achieved. The application note also outlines participation in an Emerald Scientific blind proficiency test, with acceptable results for all 66 pesticides.

A Single Cannabis Method to Meet California Pesticide and Mycotoxin Residues Regulatory Requirements

Testing for the levels of pesticide and mycotoxins in cannabis is important to ensure consumer safety and quality control. In this work, the PerkinElmer application development team analyzed all 66 pesticides (including very hydrophobic and chlorinated pesticides typically analyzed by GC-MS/MS) and five mycotoxins spiked in cannabis flower extracts well below the action limits specified by the state of California. A LC-MS/MS instrument was used with ESI and APCI sources and a simple solvent extraction method with excellent recoveries for all analytes in acceptable range of 70-120%.

Cannabis & Hemp Related Technologies