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NexION 2000C ICP Mass Spectrometer

PerkinElmer’s NexION® 2000 is the most versatile ICP-MS on the market, featuring an array of unique technologies that combine to deliver the highest performance no matter what your analytical challenge. Discover the effortless versatility of an instrument that makes it easy to handle any sample matrix, any interference, and any particle size.

PerkinElmer received on April 11, 2018 the Application Award from LaborPraxis in the category Bio and Pharma Analysis for the NexION 2000 ICP-MS. We were awarded this prize during analytica 2018 in Munich, Germany, in acknowledgment of a new technique enabling users to quantify the amount of metal in an individual cell for the first time.

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Model Name
N8150044
NexION 2000B
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N8150045
NexION 2000C
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N8150046
NexION 2000P
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N8150047
NexION 2000S
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Overview

Ideal for labs doing QA/QC or running challenging matrices, the NexION 2000C ICP-MS features:

  • A dedicated SMARTintro High Matrix sample-introduction module with integrated All Matrix Solution allows the ability to handle high dissolved solids
  • Extended Dynamic Range capabilities provide the ability to detect high-and low-level elements in a single sample run
  • Three quadrupoles, three gas channels, and three modes of operation combine to offer better interference removal, delivering better detection limits/improved data accuracy
  • The industry’s fastest data acquisition speed on the market (100,000 points/sec) to handle any particle size
  • A new solid-state RF generator with revolutionary LumiCoil technology – first ICP-MS RF coil that requires no maintenance or cooling
  • Triple Cone Interface with Quadrupole Ion Deflector, delivering no maintenance beyond the cones
  • Syngistix software provides an intuitive interface that mirrors your workflow, with left-to-right, icon-based navigation that guides you through your analysis. Plus, it’s a cross-platform solution, easing the transition from technique to technique

The NexION 2000 ICP-MS – Triple Quad Power Meets Single Quad Versatility.

Specifications

21 CFR Part 11 Compatible Yes
Depth 69.0 cm
Height 75.0 cm
Model Name NexION 2000C
Portable No
Product Brand Name NexION
Warranty 1 Year
Weight 150.0 kg
Width 81.0 cm
Resources, Events & More
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Application Brief

Arsenic Speciation Analysis in Rice Following Method GB 5009.11-2014 to Ensure Safety

Rice represents a dietary staple for over half of the world's population. However, in recent years, concerns have been raised over the presence of high levels of arsenic (As), where this carcinogenic metalloid can be accumulated at levels far exceeding ambient concentrations. Since China is the w ...

PDF 1 MB
Determination of Heavy Metals in Cassava Flours Using NexION ICP-MS Following U.S. FDA EAM 4.7 Method

Cassava is a root vegetable and a major source of calories and carbohydrates in many countries around the globe. As one of the most important staple crops, its levels of harmful chemicals and pathogens are strictly controlled – these include organic chemicals and heavy metals. Metals, such as cad ...

PDF 1 MB
Determination of Organotin in Tap Water by HPLC-ICP-MS in Accordance with Chinese Method HJ 1074-2019

Organotin compounds are widely used across industry and agriculture, resulting in widespread pollution of various environmental media, including potable water. Among these compounds are tributyltin (TBT), triphenyltin (TPT), dibutyltin (DBT), and diphenyltin (DPT), in the following order of persi ...

PDF 506 KB

Application Note

Accurate Sizing and Counting of 10 nm Gold Nanoparticles with the NexION ICP-MS

In this work, we demonstrate that PerkinElmer's NexION® 2000 ICP-MS, with its unique RF generator and ion optics, coupled with the Syngistix™ Nano Application Software Module, can be used to accurately measure and characterize NP sizes of 10 nm and smaller, both alone and in a mixture of NPs of vari ...

PDF 2 MB
Advantages of a High Throughput Sample Introduction System in the Analysis of Drinking Waters Using ICP-MS (Method 200.8)

This application note presents a high throughput method evaluating 27 analytes in drinking water following U.S. EPA 200.8 with a 3-5 fold reduction in sample analysis time through the use of the HTS high throughput sample introduction system fully integrated with the NexION® ICP-MS ...

PDF 1 MB
Analysis of Cerium Dioxide Nanoparticles in Soil Using Single Particle ICP-MS

This work demonstrates a robust method using SP-ICP-MS technology to detect CeO2 NPs which were extracted from soil samples with tetrasodium pyrophosphate (TSPP). Over the past few decades, engineered nanoparticles (ENPs) have been increasingly used in many commercial products. As a result, more and ...

PDF 1 MB
Analysis of Drinking and Natural Waters with the NexION 2000 ICP-MS

This work has demonstrated the ability of the NexION 2000 ICP-MS to analyze both natural and drinking water samples in Standard (i.e. non-cell) mode, in accordance with U.S. EPA Method 200.8. Accuracy has been demonstrated through the analysis of several reference materials and spike recoveries, wit ...

PDF 1 MB
Analysis of Milk for Major and Trace Elements by ICP-MS

Milk and milk powder are used widely in the food industry for the production of other foods. Because of its nutritional importance and widespread consumption, regulations in many countries necessitate that the quality of the milk is routinely monitored.

PDF 678 KB
Analysis of Rare Earth Elements by Laser Ablation-ICP-MS with the NexION 2000 ICP-MS

With the increasing development of high-tech applications, rare earth elements (REEs) are considered key elements for modern and future industries. Globally, there is growing pressure for analytical solutions that can accurately characterize and quantify REE content in a high-throughput manner to ...

PDF 1 MB
Analysis of Single-Walled Carbon Nanotubes with SP-ICP-MS

Measuring the amount of metals in CNTs presents a challenge. High levels can be measured directly in the solid by several techniques, including XRF and TEM, while low-level analysis requires complete digestion of the sample prior to analysis by ICP-OES or ICP-MS.

PDF 555 KB
Analysis of Soils and Waters Following U.S. EPA Method 6020B using the NexION 2000 ICP-MS

Through the years, both industry and analytical instrumentation have advanced. With the development of new chemicals and processes, new pollutants may enter the environment. However, the capabilities of analytical instruments have also increased, allowing the measurement of ever lower levels of envi ...

PDF 2 MB
Boron Isotope Ratio Analysis Using the NexION ICP-MS

Boron (B) is studied for its isotope ratio composition in a range of paleoproxy, geochemical, nuclear, medical, and archeological applications. ICP-MS is recognized as a powerful technique for boron isotope analysis. Quadrupole ICP-MS is versatile and not exclusively dedicated to isotope ratio me ...

PDF 3 MB
Characterization of TiO2 Nanoparticle Release from Fabrics By Single Particle ICP-MS

In the textile industry, the use of titanium dioxide (TiO2) nanoparticles (NPs) is increasing due to their ability to provide UV protection, increase the hydrophilic nature of fabrics, provide antibacterial characteristics, and reduce odors. This work demonstrates the ability of Perkin ...

PDF 516 KB
Determination of Impurities in Lithium Materials with the NexION 2000 ICP-MS

With growing concern about the state of the environment, more and more devices are being powered by lithium batteries due to their higher capacities, longer lives, and ability to be recycled, in comparison to conventional batteries. As with all consumer goods, safety and performance are critical ...

PDF 1 MB
Determination of Methyl and Inorganic Mercury in Fish with the NexSAR HPLC-ICP-MS Speciation Solution

Consumption of seafood is the primary exposure route of methylmercury for humans, emphasizing the importance of accurately measuring methylmercury in fish. As with all analytical method setup, the determination of methylmercury content in fish has to meet the criteria of modern analytical methodo ...

PDF 1 MB
Determination of Toxic Elements in Food Following AOAC Method 2015.01 using the NexION ICP-MS

Concentrations of toxic elements in foods are present at trace to ultra-trace levels, requiring sensitive and reliable analytical techniques for accurate measurement. ICP-MS is a powerful technique with multi-element detection capabilities, low detection limits, high speed of analysis, and wide l ...

PDF 1 MB
Determination of Toxic and Other Trace Elements in Baby Foods Using the NexION ICP-MS

For many children around the globe, commercial baby foods are the main source of nutrients and energy, and therefore their quality and safety are critical and must be monitored. In March 2021, the U.S. House of Representatives introduced the “Baby Food Safety Act of 2021” to regulate the presence ...

PDF 699 KB
Determination of Trace Elements in Eye Drops with the NexION ICP-MS

Eye drops are commonly used medications which are available both over-the-counter and as prescriptions in various forms. Because eye drops are classified as a parenteral medication and have relatively large daily doses, the inorganic components in eye drops must be present at low concentrations. ...

PDF 475 KB
Digestion, Testing, and Validation of Heavy Metals in Cannabis

Owing to the toxicity of heavy metals, it is increasingly important to test cannabis flowers and other cannabis derivatives so that patient and consumer safety is maintained as the use of cannabis becomes more common. This need has translated into an increasing demand for testing cannabis flowers ...

PDF 1 MB
Direct Analysis of Trace Elements in Coastal Seawater Using the NexION 2000 ICP-MS

With rising global populations and the increasing industrialization of both land and sea, the contamination of coastal seawater by metals and metalloids is of increasing concern. This has an adverse effect on both the biological communities which live within these waters as well as the population ...

PDF 672 KB
Extraction of Gold Nanoparticles from Fish Larvae and Soils

Gold nanoparticles (AuNPs) are widely used in industrial and medical applications. They are known to form naturally during the weathering of Au-bearing mineral deposits, as well as the transformation of gold nuggets and particles. In freshwater systems, they bioaccumulate in aquatic organisms, as ...

PDF 1 MB
Improved Analysis of Fluid Inclusions with LA-ICP-MS Using the NexION ICP-MS: Advantages of a Fast-Scanning Quadrupole

The elemental concentration of fluid inclusions in geological samples provides information about geological processes that lead to the formation of ores and minerals. Laser ablation-ICP-MS (LA-ICP-MS) is the preferred technique for measuring elemental concentrations in fluid inclusions due to its ...

PDF 1 MB
Monitoring the Fate of Silver Nanoparticles in Seawater Using Single Particle ICP-MS

Single Particle (SP) ICP-MS is an analytical technique that has demonstrated tremendous potential for the measurement and characterization of metal-containing nanoparticles (NPs) in a wide range of sample types, including environmental. One of the most challenging matrices is seawater due to its ...

PDF 1 MB
Multi-Elemental Analysis of Soils Using the NexION ICP-MS

The elemental analysis of soils is of vital importance not only for agriculture, but also from an environmental perspective. Toxic metals enter soil primarily through pollution and can be taken up directly by humans in various manners, potentially causing acute or chronically toxic responses. The ...

PDF 1 MB
New Research Evaluating Cisplatin Uptake in Ovarian Cancer Cells by Single Cell ICP-MS

Cisplatin, carboplatin, and oxaliplatin are the most widely used of platinum-based cancer chemotherapy drugs in the Western world. Cisplatin's effectiveness is due to its ability to bind to the DNA, resulting in DNA-platinum (Pt) adducts, which bend the DNA. The cells must then repair the DNA damage ...

PDF 2 MB
NexION 2000: A Perfect Tool for the Determination of Trace Elements in Blood and Serum

This work demonstrates the ability of PerkinElmer's NexION 2000 ICP-MS to perform accurate, stable analyses of blood and serum samples, leveraging the benefits of the Universal Cell and the ability to use three cell gases in a single method.

PDF 931 KB
Quantification of Low Levels of Hexavalent Chromium in Water Using a NexSAR HPLC-ICP-MS

Due to rising concerns over the carcinogenic properties of hexavalent chromium (Cr6+) in drinking water, many national and regional water standards are looking to lower the maximum allowable levels of total chromium and hexavalent chromium in potable waters. And in order to assess trac ...

PDF 1 MB
Quantification of Nanoparticle Uptake into Cancer Cells using Single Cell ICP-MS

Nanoparticles (NPs) have been of significant interest over the last two decades as they offer attractive benefits for drug delivery to overcome limitations in conventional chemotherapy. Nanoparticles can be engineered to carry both drugs and imaging probes to simultaneously detect and treat cancer. ...

PDF 906 KB
Speciation of Hexavalent Chromium in Children's Toys According to EN 71-3 Category II with the NexSAR HPLC-ICP-MS

Testing for harmful metal(loid)s that may be included in raw materials, processes, paints and additives used in the manufacturing processes of children's toys has been mandated by the regulation EN 71-3. This regulation recommends specific testing methods and maximum allowable concentrations of l ...

PDF 918 KB
Testing and Validation of Various Antacids for Elemental Impurities using the NexION 2000 ICP-MS

The United States Pharmacopeia (USP) has announced that its new standards for elemental impurities in drug products has been implemented since January 1, 2018. General Chapters <232> and <2232> specify the list of elements and their permissible daily exposure (PDE) limits based on the route of admin ...

PDF 576 KB
Transport of Nanoparticles from Coated Surfaces through Physical Contact

This work investigated the transfer of Ag and CuO nanoparticles from consumer products via simulated dermal contact by using textile wipes as a surrogate using PerkinElmer’s NexION® ICP-MS single particle analyzer with the unique Syngistix Nano Application software m ...

PDF 1 MB

Brochure

Cannabis Testing Solutions Brochure

Whether your lab is well established or just starting up, having a single-source partner who can offer turnkey solutions that meet the current regulations is essential to a successful business. For years, we’ve worked with government and contract cannabis laboratories to develop industry-leading ...

PDF 9 MB
Comprehensive Testing Solutions for Feed Millers

Feed milling today is a complex business, and agribusinesses both large and small need to balance the nutritional and safety needs of livestock with availability of raw ingredients and their seasonality and variability. Add to that the valuable supplementation and medication that millers supply, ...

PDF 3 MB
Comprehensive and Compliant Solutions for Glass Analysis

It’s clear, glass has a variety of uses, from practical to technological to decorative. In particular, float glass is widely used in architecture, automotive, transportation, photovoltaic, and solar industries.

For glass testing labs around the world, we offer highly accurate and tailored ...

PDF 2 MB
Meat and Seafood Testing Solutions

Food testing labs like yours are constantly challenged with accurately analyzing samples quickly and efficiently - all while striving to reduce costs due to market forces. Your commitment to ensuring meat and seafood are safe for consumption, as demand increases, is an uphill battle.

Our co ...

PDF 6 MB
NexION 2000 ICP Mass Spectrometer

Unrivaled ppq detection limits. Unparalleled usability. Finally analysts can have the best of both worlds with the NexION® 2000 ICP-MS, featuring an array of unique technologies that combine to deliver the highest performance no matter what your analytical challenge. Discover the e ...

PDF 1 MB
Refinery and Natural Gas Analysis

Oil refineries and natural gas producers around the world require their lab operations to perform large numbers of analyses before their products are used in industries and by consumers. Detection of even the slightest impurities, accurate process control and hydrocarbon distribution analysis is cri ...

PDF 5 MB

Catalog

Atomic Spectroscopy 2018-2019 Consumables & Supplies Catalog

With instruments that are the industry standard worldwide, PerkinElmer accessories, consumables, methods and application support meet the most demanding requirements and are the preferred choice in thousands of laboratories globally.

PDF 8 MB

Flyer

S20 Series Autosamplers

The S20 series is the next generation of high-performance, robust, and agile autosamplers designed specifically for PerkinElmer’s spectroscopy platforms - atomic and molecular. The series is comprised of two autosamplers: the S23 with three racks and the S25 with five racks. They are designed to ...

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Guide

Atomic Spectroscopy - A Guide to Selecting the Appropriate Technique and System

Atomic spectroscopy is a family of techniques for determining the elemental composition of an analyte by its electromagnetic or mass spectrum. Several analytical techniques are available:

  • Atomic absorption (AA): flame and graphite furnace
  • Inductively coupled plasma optical emis ...

PDF 2 MB
NexION 1000/2000 ICP-MS Preparing Your Laboratory

PerkinElmer ICP-MS instruments are complete systems with the exception of the following items which must be provided by the customer: electrical power, exhaust vents, argon gas supplies with approved regulator, cell gas supply with approved regulators

PDF 1 MB
NexION 1000/2000/5000 ICP-MS Consumables & Supplies Guide

Look to PerkinElmer for all of your consumables and supplies for your NexION 1000, 2000, or 5000 ICP-MS system.

PDF 3 MB

Poster

Advanced Solutions for Solar Cells Poster

Download this poster for an all-in-one view of how PerkinElmer instrumentation can answer the analytical needs of the solar market. From R&D of nanomaterials and advanced materials to solar cell component testing including aging and defect analysis - our UV/Vis, DSC, TGA, FT-IR and ICP systems he ...

PDF 1 MB
Infographic - Solutions for your Toxicology Lab

Infographic Poster showing the range of different analytical solutions for Toxicology Labs; from GC and LC, to ICP-MS and UV-Vis. Benchtop and floor standing chromatography, spectroscopy and thermal solutions for everyday robust and reliable analyses.

FOR RESEARCH USE ONLY. NOT FOR USE IN D ...

PDF 460 KB

Product Note

High Throughput System for ICP-MS and ICP-OES Product Note

Our High Throughput System (HTS) is a uniquely designed modular sample introduction that integrates with the NexION® series of ICP-MS and the Avio® series of ICP-OES to dramatically reduce sample-to-sample time, thereby improving sample throughput while maintaining o ...

PDF 1 MB
Syngistix Atomic Spectroscopy Enhanced Security Software Product Note

PerkinElmer’s Syngistix Enhanced Security software for AA, ICP and ICP-MS meets the special needs of highly regulated labs such as those that must comply with the U.S. FDA’s 21 CFR Part 11 regulations.

PDF 1 MB

Regulatory Compliance Certification

Product Certificate - NexION 1000/2000

Product Certificate for the NexION 1000/2000

PDF 98 KB

Technical Note

Advantages of a Novel Plasma Generator for the NexION 1000/2000/5000 ICP-MS Systems

Unlike other ICP-MS systems on the market that utilize conventional 40-MHz or 27-MHz commercially available generators which are typically customized and modified to work with ICP-MS instruments, the NexION® 1000/2000/5000 ICP-MS systems feature a 34-MHz frequency free-running RF g ...

PDF 986 KB
TotalQuant Analysis in NexION ICP Mass Spectrometers

TotalQuant, a software feature unique to PerkinElmer's NexION® ICP-MS systems, intelligently interprets the complete mass spectrum, providing semi-quantitative to quantitative results for all elements. TotalQuant and survey scan can provide supplementary and confirmatory information ab ...

PDF 1 MB
Unlocking Carbon-13 with Single Particle ICP-MS: Feasibility Study for Microplastic Detection

Carbon is difficult to measure with ICP-MS because of its high ionization potential and its presence in both the argon used to generate the plasma (primarily in the form of CO2, as an impurity) and in reagents, including acids and water. As a result, extremely high backgrounds exist at ...

PDF 1 MB

Training

Webinars

White Paper

The Determination of Metals in Non-Medical Face Masks

With the onset of the COVID-19 pandemic, the use of face masks by the general public has become a critical personal protective measure to minimize person-to-person transmission. While health care workers use medical or surgical masks, the general population uses non-medical, otherwise known as hy ...

PDF 683 KB