NexION 2000C ICP Mass Spectrometer | PerkinElmer
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NexION 2000C ICP Mass Spectrometer

PerkinElmer’s NexION® 2000 is the most versatile ICP-MS on the market, featuring an array of unique technologies that combine to deliver the highest performance no matter what your analytical challenge. Discover the effortless versatility of an instrument that makes it easy to handle any sample matrix, any interference, and any particle size.

PerkinElmer received on April 11, 2018 the Application Award from LaborPraxis in the category Bio and Pharma Analysis for the NexION 2000 ICP-MS. We were awarded this prize during analytica 2018 in Munich, Germany, in acknowledgment of a new technique enabling users to quantify the amount of metal in an individual cell for the first time.

Part Number
Model Name
N8150044
NexION 2000B
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N8150045
NexION 2000C
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N8150046
NexION 2000P
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N8150047
NexION 2000S
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Overview

Ideal for labs doing QA/QC or running challenging matrices, the NexION 2000C ICP-MS features:

  • A dedicated SMARTintro High Matrix sample-introduction module with integrated All Matrix Solution allows the ability to handle high dissolved solids
  • Extended Dynamic Range capabilities provide the ability to detect high-and low-level elements in a single sample run
  • Three quadrupoles, three gas channels, and three modes of operation combine to offer better interference removal, delivering better detection limits/improved data accuracy
  • The industry’s fastest data acquisition speed on the market (100,000 points/sec) to handle any particle size
  • A new solid-state RF generator with revolutionary LumiCoil technology – first ICP-MS RF coil that requires no maintenance or cooling
  • Triple Cone Interface with Quadrupole Ion Deflector, delivering no maintenance beyond the cones
  • Syngistix software provides an intuitive interface that mirrors your workflow, with left-to-right, icon-based navigation that guides you through your analysis. Plus, it’s a cross-platform solution, easing the transition from technique to technique

The NexION 2000 ICP-MS – Triple Quad Power Meets Single Quad Versatility.

Specifications

21 CFR Part 11 Compatible Yes
Depth 69.0 cm
Height 75.0 cm
Model Name NexION 2000C
Portable No
Product Brand Name NexION
Warranty 1 Year
Weight 150.0 kg
Width 81.0 cm
Resources, Events & More
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Application Brief

Arsenic Speciation Analysis in Rice Following Method GB 5009.11-2014 to Ensure Safety

Rice represents a dietary staple for over half of the world's population. However, in recent years, concerns have been raised over the presence of high levels of arsenic (As), where this carcinogenic metalloid can be accumulated at levels far exceeding ambient concentrations. Since China is the worl ...

PDF 1 MB
PM10 and PM2.5 Air Pollution Monitoring and Source Apportionment in Asia Using the NexION ICP-MS

Concern about air pollution has been growing rapidly, with most of the focus on gaseous pollutants. Airborne particulates, especially small ones, are rapidly gaining attention due to their impact on human health, as smaller particles can be carried over long distances by wind and penetrate deep into ...

PDF 1 MB

Application Note

Accurate Sizing and Counting of 10 nm Gold Nanoparticles with the NexION ICP-MS

In this work, we demonstrate that PerkinElmer's NexION® 2000 ICP-MS, with its unique RF generator and ion optics, coupled with the Syngistix™ Nano Application Software Module, can be used to accurately measure and characterize NP sizes of 10 nm and smaller, both alone and in a mixture of NPs of vari ...

PDF 2 MB
Advantages of a High Throughput Sample Introduction System in the Analysis of Drinking Waters Using ICP-MS (Method 200.8)

This application note presents a high throughput method evaluating 27 analytes in drinking water following U.S. EPA 200.8 with a 3-5 fold reduction in sample analysis time through the use of the HTS high throughput sample introduction system fully integrated with the NexION® ICP-MS and Syngistix™ fo ...

PDF 1 MB
Analysis of Cerium Dioxide Nanoparticles in Soil Using Single Particle ICP-MS

This work demonstrates a robust method using SP-ICP-MS technology to detect CeO2 NPs which were extracted from soil samples with tetrasodium pyrophosphate (TSPP). Over the past few decades, engineered nanoparticles (ENPs) have been increasingly used in many commercial products. As a result, more and ...

PDF 1 MB
Analysis of Drinking and Natural Waters with the NexION 2000 ICP-MS

This work has demonstrated the ability of the NexION 2000 ICP-MS to analyze both natural and drinking water samples in Standard (i.e. non-cell) mode, in accordance with U.S. EPA Method 200.8. Accuracy has been demonstrated through the analysis of several reference materials and spike recoveries, wit ...

PDF 1 MB
Analysis of Major and Trace Elements in Plant-Based Foods Using the NexION ICP-MS

Plant-based foods using ingredients derived from fruits, nuts, vegetables, grains, and legumes, have gained increased attention for a variety of reasons, including but not limited to nutritional, environmental, sustainability, and ethical issues. While they have many benefits, they also present chal ...

PDF 1 MB
Analysis of Milk for Major and Trace Elements by ICP-MS

Milk and milk powder are used widely in the food industry for the production of other foods. Because of its nutritional importance and widespread consumption, regulations in many countries necessitate that the quality of the milk is routinely monitored.

PDF 678 KB
Analysis of NIST Gold Nanoparticle Reference Materials Using the NexION Single Particle ICP-MS

To better understand the impact of nanoparticles, several key characteristics need to be assessed, such as concentration, composition, particle size, shape and other surface characteristics. The NexION® SP-ICP-MS, with Syngistix™ Nano Application software module, combines fast, accurate data acquisi ...

PDF 1 MB
Analysis of Rare Earth Elements by Laser Ablation-ICP-MS with the NexION 2000 ICP-MS

With the increasing development of high-tech applications, rare earth elements (REEs) are considered key elements for modern and future industries. Globally, there is growing pressure for analytical solutions that can accurately characterize and quantify REE content in a high-throughput manner to me ...

PDF 1 MB
Analysis of Single-Walled Carbon Nanotubes with SP-ICP-MS

Measuring the amount of metals in CNTs presents a challenge. High levels can be measured directly in the solid by several techniques, including XRF and TEM, while low-level analysis requires complete digestion of the sample prior to analysis by ICP-OES or ICP-MS.

PDF 555 KB
Comparison of Microsecond vs. Millisecond Dwell Times on Particle Number Concentration Measurements by Single Particle ICP-MS

With the increasing use of nanomaterials in a wide variety of products and processes, the need to measure and characterize them has also grown. Single particle ICP-MS (SP-ICP-MS) was developed specifically for metallic and metal-containing engineered nanoparticles (NPs) and is gaining popularity due ...

PDF 924 KB
Determination of Impurities in Lithium Materials with the NexION 2000 ICP-MS

With growing concern about the state of the environment, more and more devices are being powered by lithium batteries due to their higher capacities, longer lives, and ability to be recycled, in comparison to conventional batteries. As with all consumer goods, safety and performance are critical and ...

PDF 1 MB
Determination of Methyl and Inorganic Mercury in Fish with the NexSAR HPLC-ICP-MS Speciation Solution

Consumption of seafood is the primary exposure route of methylmercury for humans, emphasizing the importance of accurately measuring methylmercury in fish. As with all analytical method setup, the determination of methylmercury content in fish has to meet the criteria of modern analytical methodolog ...

PDF 1 MB
Determination of Selenium Species in Drinking Water by HPLC-ICP-MS

Selenium (Se) is an essential element at trace levels, toxic at higher levels, and exists in several oxidation states in a variety of inorganic and organic compounds. Consequently, the chemistry of selenium is complex in both the environment and biota. For the determination of selenium species in wa ...

PDF 907 KB
Determination of Trace Elements in Eye Drops with the NexION ICP-MS

Eye drops are commonly used medications which are available both over-the-counter and as prescriptions in various forms. Because eye drops are classified as a parenteral medication and have relatively large daily doses, the inorganic components in eye drops must be present at low concentrations. As ...

PDF 475 KB
Direct Analysis of Trace Elements in Coastal Seawater Using the NexION 2000 ICP-MS

With rising global populations and the increasing industrialization of both land and sea, the contamination of coastal seawater by metals and metalloids is of increasing concern. This has an adverse effect on both the biological communities which live within these waters as well as the populations w ...

PDF 672 KB
Direct Determination of Trace Elements in Nickel-Based Superalloys with the NexION 2000 ICP-MS

Nickel-based superalloys benefit from high heat resistance, high melting points, retention of mechanical and chemical properties at high temperatures, and high corrosion resistance, among others, and are therefore widely used in challenging environments, such as aircraft and power generation turbine ...

PDF 916 KB
Elemental Analysis of Wines using the NexION 2000 ICP-MS with TotalQuant

Food alteration has been increasing substantially in recent years, leading to substandard products. Therefore, to ensure the health and safety of the consumer, it is essential to characterize foods for toxic and nutritional elements accurately and rapidly, and ICP-MS is the ideal technique for these ...

PDF 974 KB
Extraction of Gold Nanoparticles from Fish Larvae and Soils

Gold nanoparticles (AuNPs) are widely used in industrial and medical applications. They are known to form naturally during the weathering of Au-bearing mineral deposits, as well as the transformation of gold nuggets and particles. In freshwater systems, they bioaccumulate in aquatic organisms, as sh ...

PDF 1 MB
Improved Analysis of Fluid Inclusions with LA-ICP-MS Using the NexION ICP-MS: Advantages of a Fast-Scanning Quadrupole

The elemental concentration of fluid inclusions in geological samples provides information about geological processes that lead to the formation of ores and minerals. Laser ablation-ICP-MS (LA-ICP-MS) is the preferred technique for measuring elemental concentrations in fluid inclusions due to its ab ...

PDF 1 MB
Iron Nanoparticles by SP-ICP-MS: Overcoming Spectral Interferences Using Universal Cell Technology

With the increasing interest in nanoparticles (NPs), various ways of detecting and measuring them are being used. One of the most promising techniques for analyzing metallic NPs is single particle ICP-MS (SP-ICP-MS). This work demonstrates the ability of the NexION® SP-ICP-MS with Universal Cell Tec ...

PDF 1 MB
Measurement of Titanium Dioxide Nanoparticles in Sunscreen using Single Particle ICP-MS

Titanium dioxide (TiO2) nanoparticles are commonly used in sunscreens as part of the formulation to block the sun’s harmful UV rays. As the use of nanoparticles (NPs) in consumer products has increased, concern has risen as to the health and environmental effects of nanoparticles. Since sunscreens c ...

PDF 1 MB
Multi-Elemental Analysis of Soils Using the NexION ICP-MS

The elemental analysis of soils is of vital importance not only for agriculture, but also from an environmental perspective. Toxic metals enter soil primarily through pollution and can be taken up directly by humans in various manners, potentially causing acute or chronically toxic responses. Theref ...

PDF 1 MB
New Research Evaluating Cisplatin Uptake in Ovarian Cancer Cells by Single Cell ICP-MS

Cisplatin, carboplatin, and oxaliplatin are the most widely used of platinum-based cancer chemotherapy drugs in the Western world. Cisplatin's effectiveness is due to its ability to bind to the DNA, resulting in DNA-platinum (Pt) adducts, which bend the DNA. The cells must then repair the DNA damage ...

PDF 2 MB
NexION 2000: A Perfect Tool for the Determination of Trace Elements in Blood and Serum

This work demonstrates the ability of PerkinElmer's NexION 2000 ICP-MS to perform accurate, stable analyses of blood and serum samples, leveraging the benefits of the Universal Cell and the ability to use three cell gases in a single method.

PDF 931 KB
Quantification of Low Levels of Hexavalent Chromium in Water Using a NexSAR HPLC-ICP-MS

Due to rising concerns over the carcinogenic properties of hexavalent chromium (Cr6+) in drinking water, many national and regional water standards are looking to lower the maximum allowable levels of total chromium and hexavalent chromium in potable waters. And in order to assess trace concentratio ...

PDF 1 MB
Quantification of Nanoparticle Uptake into Cancer Cells using Single Cell ICP-MS

Nanoparticles (NPs) have been of significant interest over the last two decades as they offer attractive benefits for drug delivery to overcome limitations in conventional chemotherapy. Nanoparticles can be engineered to carry both drugs and imaging probes to simultaneously detect and treat cancer. ...

PDF 906 KB
SP-ICP-MS Analysis of Size and Number Concentration in Mixtures of Monometallic and Bimetallic (Core-shell) Nanoparticles

Separating and measuring the physical and chemical properties of monometallic and bimetallic engineered nanoparticles (NPs) is challenging, especially when mixtures of NPs consist of particles of similar size, composition, and especially when present at low concentrations. Fully characterizing suspe ...

PDF 1 MB
Testing and Validation of Various Antacids for Elemental Impurities using the NexION 2000 ICP-MS

The United States Pharmacopeia (USP) has announced that its new standards for elemental impurities in drug products has been implemented since January 1, 2018. General Chapters <232> and <2232> specify the list of elements and their permissible daily exposure (PDE) limits based on the route of admin ...

PDF 576 KB
Transport of Nanoparticles from Coated Surfaces through Physical Contact

This work investigated the transfer of Ag and CuO nanoparticles from consumer products via simulated dermal contact by using textile wipes as a surrogate using PerkinElmer’s NexION® ICP-MS single particle analyzer with the unique Syngistix™ Nano Application software module for data collection and an ...

PDF 1 MB

Brochure

Comprehensive Testing Solutions for Feed Millers

Feed milling today is a complex business, and agribusinesses both large and small need to balance the nutritional and safety needs of livestock with availability of raw ingredients and their seasonality and variability. Add to that the valuable supplementation and medication that millers supply, and ...

PDF 3 MB
Grain Testing Solutions Brochure

The grain industry is very complex. It’s global, diverse, and can also present analytical challenges. Today’s grain users demand more when it comes to quality, safety, and uniformity. In addition, they seek diverse products with unique characteristics. PerkinElmer is equipped to help the grain indus ...

PDF 6 MB
Refinery and Natural Gas Analysis Brochure

Oil refineries and natural gas producers around the world require their lab operations to perform large numbers of analyses before their products are used in industries and by consumers. Detection of even the slightest impurities, accurate process control and hydrocarbon distribution analysis is cri ...

PDF 5 MB
USP <232>/<233> & ICH Q3D Capabilities Brochure

The International Conference on Harmonization Guideline for Elemental Impurities Q3D (ICH Q3D) has established maximum permitted daily exposure limits for elemental impurities in pharmaceutical products. In combination with the U.S. Pharmacopeia’s (USP) Chapters <232> and <233> on elemental impuriti ...

PDF 3 MB

Catalog

Atomic Spectroscopy Consumables Catalog

Download your complete PDF catalog containing all the consumables needed to keep your Atomic Absorption, ICP-OES, and ICP-MS instruments up and running.

PDF 8 MB

Flyer

S20 Series Autosamplers

The S20 series is the next generation of high-performance, robust, and agile autosamplers designed specifically for PerkinElmer’s spectroscopy platforms - atomic and molecular. The series is comprised of two autosamplers: the S23 with three racks and the S25 with five racks. They are designed to mee ...

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Supporting Sustainability with the NexION ICP-MS Series

Today’s sustainable solutions are opening exciting new ways for businesses to fuel economic growth, while minimizing adverse impact on people and the planet. Laboratories are also working sustainability into their business plans to reduce downtime, waste, and costs – and in many cases, improve their ...

PDF 587 KB

Guide

Atomic Spectroscopy - A Guide to Selecting the Appropriate Technique and System

Atomic spectroscopy is a family of techniques for determining the elemental composition of an analyte by its electromagnetic or mass spectrum. Several analytical techniques are available: Atomic absorption (AA): flame and graphite furnace Inductively coupled plasma optical emission spectroscopy (ICP ...

PDF 1 MB
NexION ICP-MS Series Consumables & Supplies Guide

Whether looking for sample introduction components or standards, we have the consumables you need to keep your NexION up and running smoothly and efficiently.

PDF 2 MB

Poster

Advanced Solutions for Solar Cells Poster

Download this poster for an all-in-one view of how PerkinElmer instrumentation can answer the analytical needs of the solar market. From R&D of nanomaterials and advanced materials to solar cell component testing including aging and defect analysis - our UV/Vis, DSC, TGA, FT-IR and ICP systems help ...

PDF 1 MB
Infographic - Solutions for your Toxicology Lab

Infographic Poster showing the range of different analytical solutions for Toxicology Labs; from GC and LC, to ICP-MS and UV-Vis. Benchtop and floor standing chromatography, spectroscopy and thermal solutions for everyday robust and reliable analyses. FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC ...

PDF 460 KB

Product Note

Syngistix Atomic Spectroscopy Enhanced Security Software Product Note

PerkinElmer’s Syngistix Enhanced Security software for AA, ICP and ICP-MS meets the special needs of highly regulated labs such as those that must comply with the U.S. FDA’s 21 CFR Part 11 regulations.

PDF 1 MB

Regulatory Compliance Certification

Technical Note

Advantages of Short Settling Times for Quadrupole-Based ICP-MS Laser Ablation Imaging

Laser ablation-ICP-MS (LA-ICP-MS) has become an increasingly popular tool for imaging due to its ability to provide spatially resolved elemental information at low concentrations. Many aspects need to be considered when setting up an LA-ICP-MS system for imaging. Laser scanning speed, stage accuracy ...

PDF 2 MB
Advantages of a Novel Plasma Generator for the NexION 1000/2200/5000 ICP-MS Systems

Unlike other ICP-MS systems on the market that utilize conventional 40-MHz or 27-MHz commercially available generators which are typically customized and modified to work with ICP-MS instruments, the NexION® 1000/2200/5000 ICP-MS systems feature a 34-MHz frequency free-running RF generator, which wa ...

PDF 1 MB
TotalQuant Analysis in NexION ICP Mass Spectrometers

TotalQuant, a software feature unique to PerkinElmer's NexION® ICP-MS systems, intelligently interprets the complete mass spectrum, providing semi-quantitative to quantitative results for all elements. TotalQuant and survey scan can provide supplementary and confirmatory information about unknown sa ...

PDF 1 MB

Training

Webinars

White Paper

The Determination of Metals in Non-Medical Face Masks

With the onset of the COVID-19 pandemic, the use of face masks by the general public has become a critical personal protective measure to minimize person-to-person transmission. While health care workers use medical or surgical masks, the general population uses non-medical, otherwise known as hygie ...

PDF 683 KB