Ideal for analyzing food, cannabis, and environmental samples, our robust and reliable QSight® triple quad systems consistently deliver the throughput and productivity you need in your analytical testing lab. Now we’ve added the premier model to our QSight family: the high performance 400 series. This ready-to-implement solution has the highest sensitivity and throughput the industry has ever seen and the capability to test for the most challenging, complex samples, including cannabis.
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This workhorse system provides exceptional sensitivity for difficult matrices in commercial testing labs and the food, environmental, and cannabis industries – it’s the perfect instrument for labs that need uncompromising performance.
Achieve the highest levels of performance from sample handling right through results and reporting with QSight triple quad LC/MS/MS systems.
| Model Name | QSight 200 Series |
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QSight LC/MS/MS evaluates eliminating sample preparation for trace level pesticide in wine
A New, Sensitive Method for Lignan Metabolite Detection of Flaxseed-Fed Mice Using LC/MS/MS
Aflatoxin B1 is considered to be the most genotoxic of the mycotoxins, and, when ingested by cows, is converted to aflatoxin M1 which has been shown to cause liver cancer in certain animals.
Benzo[a]pyrene (B[a]P) is a well-known carcinogenic compound found in tobacco products and tobacco smoke. The Cooperation Centre for Scientific Research Relative to Tobacco (CORESTA) has recommended a gas chromatography/ mass spectrometry (GC/MS) method to determine concentrations of B[a]P in tobacco products. In the proposed method, B[a]P is extracted from the tobacco with methanol, followed by a solid phase extraction (SPE) and subsequent concentration prior to GC/MS analysis. The CORESTA recommended method is time-consuming, especially in sample preparation procedures, and showed low sensitivity. In this application note, a simple, reliable and fast analytical method for the determination and quantification of B[a]P in tobacco products has been developed using a PerkinElmer QSight® LX50 UHPLC system, coupled to a PerkinElmer QSight 220 MS/MS detector.
Haloacetic acids (HAAs) are a class of undesired by-products resulting from the reaction of chlorinated disinfectants with natural organic matter in water. The resulting substances are considered major disinfection by-products (DBP), which are known for being carcinogenic and also associated with reproductive problems in humans. The five major HAAs of particular concern include monochloroacetic acid (MCAA), monobromoacetic acid (MBAA), dichloroacetic acid (DCAA), dibromoacetic acid (DBAA) and trichloroacetic acid (TCAA). Haloacetic acids are regulated by the U.S. Environmental Protection Agency (EPA) government. In this application note, a reliable and fast method for determination and quantification of five HAAs in potable drinking water is presented using a PerkinElmer QSight® LX50 UHPLC system coupled to a PerkinElmer QSight 220 MS/MS detector. The five HAAs eluted within three minutes with excellent reproducibility.
Mycotoxins produced by fungi as toxic secondary metabolites, leave grains, maize and cereals particularly vulnerable. With this in mind, and considering that an estimated 25% of all crops show some signs of mycotoxin contamination, many countries have established regulatory guidelines for maximum mycotoxin limits in not only feed and grain, but also in processed food products.
Pharmaceutical and Personal Care Products (PPCPs) are an emerging environmental concern, and include human and veterinary prescription and over-the-counter medications, sunscreens, lotions, soaps, and insect repellants. These commonly encountered products can enter the environment through various sources, including municipal wastewater, polluting ground water, surface water, and even drinking water. The analytical challenge associated with PPCP testing is the wide variety of chemical classes/ types that are typically present at parts per trillion (ng/L) concentrations in drinking water. The automated approach described in this application note allows for significant and efficient analyte concentration, obviating the need for elaborate and time-consuming sample preparation procedures, and thus improving productivity, reducing solvent usage and laboratory waste.
Liquid chromatography-tandem mass spectrometry (LC/MS/MS) has become the method of choice for pesticide The state of Oregon has issued regulatory limits for 59 pesticide residues in both cannabis flower and concentrates, while other states have come up with
Analysis of target pesticide residues in berries using a unique laminar flow UHPLC-ESI-MS/MS
Water-soluble vitamins (WSV), comprised primarily of the vitamin B complex, are essential ingredient
Mycotoxins are toxic secondary metabolites produced by fungi, and are capable of causing disease and death in both humans and animals. Sample preparation is a critical step in the successful analysis of mycotoxins in food matrices. The “dilute and shoot” approach is a quick and easy way to introduce the sample into the LC/MS/MS analysis. However, due to the complexity of food matrices, this approach will often result in irreproducible matrix effects. To overcome these problems and improve sensitivity, this application note details the use of online solid phase extraction (SPE), coupled to an LC/MS/MS system for sample enrichment.
In this work, we present a fast and sensitive LC/MS/MS method
Analysis of glyphosate and similiar polar pesticides in oatmeal using the PerkinElmer QSight LCMSMS.
Endocrine disrupting chemicals (EDCs) have been found to have harmful effects on the health of both humans and wildlife. Of these EDCs, endogenous estrogens, such as estriol, 17ß-estriadiol, and estrone are of particular interest due to their potency/physiological activity even at very low levels. These hormones are particularly challenging to monitor, as concentrations are typically expected to be in the low ng/mL (ppb) to low pg/mL (ppt) range.
To improve sensitivity, this work utilizes the addition of on-line solid phase extraction (SPE) coupled to an LC/MS/MS system for sample enrichment and quantitation. This approach allows for significant/efficient analyte concentration, obviating the need for elaborate and time-consuming sample preparation procedures. Due to enrichment, compared to other methods, large sample volumes (= ½ liter) are no longer needed to reach part per trillion levels for estrogen monitoring in river water.
Aniline and aniline derivatives are widely used as raw materials and intermediates in the polymer, rubber, dye, pesticide and pharmaceutical industries. Unintended releases of aniliane or its derivatives into the environment pose a serious threat, with release possible during any stage of production, storage, transport, use, or disposal. Therefore, it is important and necessary to develop fast, simple, sensitive, selective and efficient methods for the determination of aniline and its derivatives in drinking and environmental waters. The aim of this study is to develop an LC/MS/MS method for rapid analysis of aniline and its derivatives in water samples by direct injection, without using time consuming sample preparation steps.
This application note presents a sensitive and reliable LC/MS/MS method using the PerkinElmer QSight
A simple and sensitive method for the simultaneous determination of plant growth regulators
Learn more about our various testing methods and applications for cannabis analyses by reading through our Cannabis Testing brochure.
The grain industry is very complex. It’s global, diverse, and can also present analytical challenges. Today’s grain users demand more when it comes to quality, safety, and uniformity. In addition, they seek diverse products with unique characteristics.
PerkinElmer is equipped to help the grain industry in its quest to feed the world – nutritiously and economically. Our testing and analysis solutions encompass the three primary areas required for complete knowledge of grains and their derivatives – composition, functionality, and safety.
Pesticides can adversely affect human health through the food we consume but can also leach into soil and groundwater and impact us through the environment. To keep up with a complex and constantly changing regulatory environment, your pesticide analysis solution needs to keep up with your burgeoning sample load.
Our QSight triple quad LC/MS/MS family has always been known for its robust and reliable performance. But now there’s something new – something better: the high performance 400 series. Our ready-to-implement solution has the highest sensitivity and throughput the industry has ever seen and the capability to test for the most challenging samples and analytes.
Whether you’re a lab manager or a bench chemist, you know firsthand how things are changing quickly in food and environmental analysis. And your lab needs to change to keep pace.
Our QSight triple quad LC/MS/MS family has always been known for its robust and reliable performance. But now there’s something new – something better: the high performance 400 series.
Our modular Simplicity 3Q™ software is ideal for acquiring, quantifying and reporting
Lab reequirements for QSight triple quad LC/MS/MS systems, including storage, suppleis, space, electrical, power, gas supply requirements
Product Certificate for the QSight 110 & 120
Product Certificate for the QSight 210 & 220
Simulation using sophisticated modeling techniques has become a powerful tool for mass spectrometry
Ion Transmission Through a Quadrupole Ion Guide Under the Combined Influence of Viscous Flow and RF
Theoretical Studies of Swirling Flow and Heating Methods on Droplet Evaporation in a Heated Coaxial
