Our QSight® LX50 UHPLC integrates seamlessly to our QSight Triple Quad LC/MS/MS and its Simplicity™ software to deliver the highest levels of performance from sample handling through data collection and reporting. The system includes three key technologies that help optimize your workflow and enable high productivity.
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For the QSight triple quad LC/MS/MS, we’ve paired the industry’s most flexible mass spectrometer with the equally capable QSight LX50 UHPLC system, delivering all the sensitivity and specificity you need for demanding applications such as pesticide-residue and nutritional-component analysis. And with its robust design and carryover-elimination capabilities, the system is perfect for a host of other applications in the food and environmental arenas.
QSight LC/MS/MS evaluates eliminating sample preparation for trace level pesticide in wine
A New, Sensitive Method for Lignan Metabolite Detection of Flaxseed-Fed Mice Using LC/MS/MS
Aflatoxin B1 is considered to be the most genotoxic of the mycotoxins, and, when ingested by cows, is converted to aflatoxin M1 which has been shown to cause liver cancer in certain animals.
Mycotoxins produced by fungi as toxic secondary metabolites, leave grains, maize and cereals particularly vulnerable. With this in mind, and considering that an estimated 25% of all crops show some signs of mycotoxin contamination, many countries have established regulatory guidelines for maximum mycotoxin limits in not only feed and grain, but also in processed food products.
Liquid chromatography-tandem mass spectrometry (LC/MS/MS) has become the method of choice for pesticide The state of Oregon has issued regulatory limits for 59 pesticide residues in both cannabis flower and concentrates, while other states have come up with
Analysis of target pesticide residues in berries using a unique laminar flow UHPLC-ESI-MS/MS
Water-soluble vitamins (WSV), comprised primarily of the vitamin B complex, are essential ingredient
Antibiotics are used in dairy cattle for different treatments, but it leads to accumulation of these residues in milk. Presence of such residues in human food can be responsible for allergic reactions, toxic effects and develops resistant strains of bacteria. To protect consumers, regulatory agencies in the European Union published several official documents to regulate the control of veterinary drugs. Council Directive 96/23/EC establishes the veterinary residue control in food producing animals. In India, as per FSSAI (gazette notification dated 20th July 2018) and EIC (RMP for Aquaculture, Egg, Honey, Milk Poultry etc.) it is a mandate to do the analysis of antibiotics. EIC and FSSAI both have maximum residue limits (MRLs) for various antibiotic residues for food matrices from animals. It is essential to test milk for residues of sulfonamides considering safety and prevent exposure of consumers to veterinary drugs. In this work, we present a fast and sensitive LC-MS/MS method for the quantitative analysis of sulfonamides antibiotics in milk.
In this work, we present a fast and sensitive LC/MS/MS method
Analysis of glyphosate and similiar polar pesticides in oatmeal using the PerkinElmer QSight LCMSMS.
It is very well known that Black pepper is a complex matrix that requires a proper extraction and clean-up method for interferences. In this study, a fast, sensitive and selective multi-residue method has been developed for analysis of over 136 pesticides in Pepper samples by coupling a modified QuEChERS extraction method with LC/MS/MS. Using time-managed- MRM™ in the QSight™ triple quadrupole mass spectrometer, the optimum dwell time of multiple MRM transitions can be generated automatically for the targeted analytes. This not only saves time in method development but also improves data quality and analytical performance of instrument.
EU water policies are reevaluated on a consistent basis to ensure water sources do not contain contaminants at levels above regulatory levels. As regulations are reviewed, regulatory limits are often lowered, and analytical techniques mush adapt to meet the new stringent requirements.
In this application note, an LC/MS/MS method for the determination of 214 regulated contaminants is presented. The direct injection method, utilizing a PerkinElmer® QSight 420, is optimized with the use of dual ionization sources (APCI and ESI). Additionally, an inter-laboratory study is detailed to illustrate the method transferability between instruments, utilizing the compound Atrazine.
N-nitroso dimethylamine (NDMA) is one of nitrosamine class impurities classified as a probable human carcinogen (a substance that could cause cancer). NDMA is a known environmental contaminant and found in water and foods, including meats, dairy products and vegetables. The European Medicines Agency (EMA) and theUS Food and Drug Administration (US FDA) have been investigating NDMA and similar nitrosamines compounds since 2018 when they were found in a number of angiotensin II receptor blockers (ARBs), blood pressure medicines known as ‘sartans’, leading to some recalls.
The use of cannabis concentrates and CBD products (edibles, topicals, vape products, etc.) has increased in popularity as new regulation has been passed legalizing medicinal and recreational use in a number of states and provinces. Testing to ensure that pesticide and mycotoxin levels in cannabis products are below regulatory levels is critical, however, the cannabis concentrate matrix presents many analytical challenges including higher sample matrix effects and an increased concentration of cannabinoids in the sample.
In this application note, an LC/MS/MS method for the analysis of 66 pesticides (including hydrophobic and chlorinated pesticides typically analyzed by GC/MS/MS) and five mycotoxins in a cannabis concentrate matrix is presented. Utilizing a QSight® 420 LC/MS/MS instrument with dual APCI and ESI sources, the analysis yielded excellent recoveries and detection limits below those specified by the state of California cannabis regulations.
Aniline and aniline derivatives are widely used as raw materials and intermediates in the polymer, rubber, dye, pesticide and pharmaceutical industries. Unintended releases of aniliane or its derivatives into the environment pose a serious threat, with release possible during any stage of production, storage, transport, use, or disposal. Therefore, it is important and necessary to develop fast, simple, sensitive, selective and efficient methods for the determination of aniline and its derivatives in drinking and environmental waters. The aim of this study is to develop an LC/MS/MS method for rapid analysis of aniline and its derivatives in water samples by direct injection, without using time consuming sample preparation steps.
This application note presents a sensitive and reliable LC/MS/MS method using the PerkinElmer QSight
A simple and sensitive method for the simultaneous determination of plant growth regulators
Pesticides can adversely affect human health through the food we consume but can also leach into soil and groundwater and impact us through the environment. To keep up with a complex and constantly changing regulatory environment, your pesticide analysis solution needs to keep up with your burgeoning sample load.
Whether you’re a lab manager or a bench chemist, you know firsthand how things are changing quickly in food and environmental analysis. And your lab needs to change to keep pace.
Our modular Simplicity 3Q™ software is ideal for acquiring, quantifying and reporting
Lab reequirements for QSight triple quad LC/MS/MS systems, including storage, suppleis, space, electrical, power, gas supply requirements
Simulation using sophisticated modeling techniques has become a powerful tool for mass spectrometry
Ion Transmission Through a Quadrupole Ion Guide Under the Combined Influence of Viscous Flow and RF
Theoretical Studies of Swirling Flow and Heating Methods on Droplet Evaporation in a Heated Coaxial