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Application Note

Analysis of Pesticide Residues in Cannabis Regulated by Oregon State Using LC/MS/MS

Introduction

Liquid chromatography-tandem mass spectrometry (LC/MS/MS) has become the method of choice for pesticide The state of Oregon has issued regulatory limits for 59 pesticide residues in both cannabis flower and concentrates. In this study, all 59 pesticides were spiked into cannabis flower samples and analyzed by coupling QuEChERS sample preparation with LC/MS/MS. All the 59 pesticides in Oregon’s regulated list were detected using this methodology, with results well below the current action limits specified. Recoveries of pesticides from spiked cannabis flower extracts are shown to be between 70-120%.