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LAMBDA 365 UV/Vis Spectrophotometer

The LAMBDA 365 delivers state-of-the-art UV Vis performance that meets the needs of pharmaceuticals, analytic chemists, geneticists, and manufacturing QA/QC analysts everywhere. With 21 CFR part 11 compliant software available, the LAMBDA system is ready to support everything from standard methods and applications to those requiring regulatory compliance.

Part Number N4100020
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Compact, versatile, easy-to-use double-beam UV Vis

With 21 CFR part 11 compliant software available, the LAMBDA system is ready to support everything from standard methods and applications to those requiring regulatory compliance.

The system delivers a variable spectral bandwidth capability from 0.5 nm to 20 nm, to meet your application needs. It can accommodate a wide range of accessories, including multicell changers (both water and Peltier temperature-controlled), solid sample accessories for transmission and reflectance, optical fiber probes for remote measurements, an integrating sphere for color and diffuse measurements, and a range of cuvette holders to meet your sampling requirements.

When high stability and low stray light are critical, the LAMBDA 365 double-beam technology is the ideal solution. The large sample compartment can easily accommodate more than 10 sampling accessory combinations. Easy-to-install accessories minimize setup time and effort, and multicell changers are autoaligned by the instrument software to optimize the sample position for the best results in a wide range of routine applications.


21 CFR Part 11 Compatible Yes
Height 27.0 cm
Interface Tungsten-halogen and Deuterium
Maximum Temperature 35 °C
Minimum Temperature 15 °C
Model Name LAMBDA 365
Operating Range 190 - 1100 nm
Portable No
Product Brand Name LAMBDA
Research Areas Food & Agriculture
Warranty 1 year
Weight 20.0 kg
Width 49.0 cm
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Application Note

Pharmaceutical Assay and Multicomponent Analysis using the LAMBDA 365 UV/Vis Spectrophotometer

Combination drugs containing Paracetamol and Aspirin are widely used analgesics with anti-inflammatory properties for treatment of migraines. UV/Vis spectrometry is a fast and commonly used technique in quality control laboratories for routine analysis of purity and quantity of components within various stages of a product’s manufacture in many industries. This application describes the efficient use of the LAMBDA 365 UV/Vis spectrometer in determining the quantity and percent assay of Paracetamol according to U.S. Pharmacopeia’s (USP) methods, and component concentration in pharmaceutical formulations, while achieving 21 CFR Part 11 compliance.

Quantification of Sodium Hypochlorite in Disinfectants

Sodium hypochlorite is one of the most common disinfectants used in both domestic and commercial settings and has been included on the environmental protection agency (EPA) list of disinfectants recommended for use against COVID-19. This has resulted in a sharp rise in the production and use of sodium hypochlorite for disinfecting household and workplace environments. While safe handling practices need to be implemented along with the use of personal protective equipment (PPE), there is also a need for quality control to ensure manufacturers stay within the acceptable limits of sodium hypochlorite in domestic and industrial-strength bleaches to limit exposure and damage to humans.

The standard method for the determination of hypochlorite is an iodometric titration which, despite being very useful, requires several chemical reagents and can therefore be time consuming and costly when running many samples. This application brief describes how the PerkinElmer LAMBDA® 365 UV/Vis spectrometer provides a simple and fast solution for the measurement of sodium hypochlorite within 30 seconds and without the need for several reagents, allowing analysts working in a QA/QC environment to save time and expenditure.



A Guide to General USP Chapters

Quality and consistency of medicines is critical to ensuring their identity, strength, and purity is at a safe level for human consumption.

That's why we rely on strict guidelines – to guarantee medications that make it to the shelves are exactly what they claim to be. This guide helps provide a simple breakdown of USP Chapters and what they contain, so that you can be confident your products are in compliance.

Dissolution Testing Brochure

Pharmaceutical labs consider dissolution testing to be one of the critical steps in the drug development process. It makes an impact at almost every step of the journey, from early product development to late-stage quality control - so it's no surprise that it is a key concern for regulatory bodies. To ensure quality and compliance in your lab, the dissolution testing solution you depend on must provide the most accurate and reproducible results available.

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Meat and Seafood Testing Solutions

Food testing labs like yours are constantly challenged with accurately analyzing samples quickly and efficiently - all while striving to reduce costs due to market forces. Your commitment to ensuring meat and seafood are safe for consumption, as demand increases, is an uphill battle.

Our commitment to you: to provide a range of solutions across multiple technologies, products, and services that meets or exceeds the testing needs of food processors. Our solutions offer more efficiency and increased accuracy and sensitivity for better yields in real time with minimal training.

From instrumentation and software to consumables and reagents to service and support, we are dedicated to providing you with end-to-end solutions that ease your everyday challenges of automation, throughput, service, and time to results.



Palm Oil Analysis. Complete lab solutions from upstream to downstream

Quality control-monitoring and testing are important in ensuring the quality of palm oil. The quality control parameters are used to judge the quality of palm oil products and it can be monitored and tested to ensure that the palm oil is not deliberately or accidentally adulterated.



Are you Compliant with the Latest USP 857 Guidelines?

Revision to General Chapter USP 857, which emphasized on performance specifications for UV-Vis Spectrometers (e.g. Lambda 365), on December 1st 2019 USP officially announced the amended chapter with new regulations on testing parameters. There are some major modifications made related to calibration parameters which will supersede the earlier method protocols that were practiced in the regulated environment of QA/QC lab. This PerkinElmer note gives a quick look at the parameter changes and additions to the test limits and wavelengths to be tested.



Infographic - Solutions for your Toxicology Lab

Infographic Poster showing the range of different analytical solutions for Toxicology Labs; from GC and LC, to ICP-MS and UV-Vis. Benchtop and floor standing chromatography, spectroscopy and thermal solutions for everyday robust and reliable analyses.


PDF 460 KB

Regulatory Compliance Certification

Product Certificate - UV Lambda 365

Product Certificate for the UV Lambda 365

PDF 117 KB