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Application Note

Pharmaceutical Assay and Multicomponent Analysis using the LAMBDA 365 UV/Vis Spectrophotometer

Introduction

Combination drugs containing Paracetamol and Aspirin are widely used analgesics with anti-inflammatory properties for treatment of migraines. UV/Vis spectrometry is a fast and commonly used technique in quality control laboratories for routine analysis of purity and quantity of components within various stages of a product’s manufacture in many industries. This application describes the efficient use of the LAMBDA 365 UV/Vis spectrometer in determining the quantity and percent assay of Paracetamol according to U.S. Pharmacopeia’s (USP) methods, and component concentration in pharmaceutical formulations, while achieving 21 CFR Part 11 compliance.