The NexSAR™ HPLC, is a next-generation Speciation Analysis Ready system engineered with a completely inert and metal-free fluid path, enabling laboratories to meet low chromatographic background requirements on the most challenging speciation applications. Plus, it is fully customizable, with the flexibility to select only the parts that you need for your application(s).
This system is part of the NexSAR HPLC-ICP-MS Speciation Solution, which couples the NexSAR HPLC with our revolutionary NexION® ICP-MS and is seamlessly integrated using the proven Clarity™ software.
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Rice represents a dietary staple for over half of the world's population. However, in recent years, concerns have been raised over the presence of high levels of arsenic (As), where this carcinogenic metalloid can be accumulated at levels far exceeding ambient concentrations. Since China is the world's largest producer of rice, the Chinese government released a national standard method in 2014 for food safety – GB 5009.11– to aid the evaluation of As species in rice and rice products. In this document, HPLC-ICP-MS is identified as the preferred analytical technique.
In this study, five arsenic species were characterized in a commercial rice sample and certified reference material using a gradient anion-exchange method in accordance with GB 5009.11. The analysis was performed using a PerkinElmer NexSAR™ HPLC-ICP-MS speciation solution, consisting of a NexSAR inert HPLC coupled to a NexION® ICP-MS.
Although apple juice is a healthy, and often preferred, alternative to artificially flavored and carbonated drinks for many parents to give to children, concern has been raised over the presence of arsenic within. This work demonstrates a reversed-phase ion-pairing method for the complete separation and accurate quantification of the main and most toxicologically relevant arsenic species in commercially available apple juices, using a PerkinElmer NexSAR HPLC-ICP-MS system.
Breakfast is an important meal in providing essential nutrients to keep your energy levels up throughout the day. How do we ensure the food and beverages we consume are healthy, nutritious and safe? Following is a collection of application notes highlighting solutions that will help you identify micronutrients in milk, cereal, juice and fresh and dried fruits as well as toxic metals in tea, dairy products and apple juice to ensure safety of your breakfast foods.
Consumption of seafood is the primary exposure route of methylmercury for humans, emphasizing the importance of accurately measuring methylmercury in fish. As with all analytical method setup, the determination of methylmercury content in fish has to meet the criteria of modern analytical methodology, including reproducibility, repeatability, and accuracy at low concentrations. These characteristics are facilitated by using an HPLC system with a metal-free flow path, which eliminates the possibility of mercury leaching into the mobile phase, thereby affecting the lowest concentrations which can be measured.
This work demonstrates the accurate and reliable determination of methyl- and inorganic mercury in fish using PerkinElmer’s NexSAR™ HPLC-ICP-MS speciation solution, leveraging the inert, metal-free flow path of the NexSAR HPLC system in combination with the robust and versatile NexION® ICP-MS.
Due to rising concerns over the carcinogenic properties of hexavalent chromium (Cr6+) in drinking water, many national and regional water standards are looking to lower the maximum allowable levels of total chromium and hexavalent chromium in potable waters. And in order to assess trace concentrations of Cr6+ in drinking water, it is necessary to have an instrument capable of measuring parts per trillion (ppt) concentrations of Cr and possessing a wide linear dynamic range – HPLC-ICP-MS is often the instrumentation of choice in such applications.
This work demonstrates an ion exchange method for the characterization of Cr6+ in potable drinking water using our NexSAR HPLC-ICP-MS Speciation Solution. Discover the advantages of the inert and metal-free fluid path of the NexSAR Inert HPLC coupled with the NexION® ICP-MS’ Universal Cell Technology™ for these types of analyses – download this application note.
Testing for harmful metal(loid)s that may be included in raw materials, processes, paints and additives used in the manufacturing processes of children's toys has been mandated by the regulation EN 71-3. This regulation recommends specific testing methods and maximum allowable concentrations of leachable metals and metalloids such as Al, As, B, Ba, Cd, Co, Cr (III), Cr (VI), Cu, Hg, Mn, Ni, Pb, Sb, Se, Sn, organotin, Sr and Zn in parts of toys, with the exclusion of general packaging materials.
This work shows a method for the measurement of hexavalent chromium in different toy material categories in accordance with method EN 71-3 Category II, leveraging the unique combination and capabilities of the NexSAR™ Inert HPLC coupled to the robust NexION® ICP-MS.
Food testing labs like yours are constantly challenged with accurately analyzing samples quickly and efficiently - all while striving to reduce costs due to market forces. Your commitment to ensuring meat and seafood are safe for consumption, as demand increases, is an uphill battle.
Our commitment to you: to provide a range of solutions across multiple technologies, products, and services that meets or exceeds the testing needs of food processors. Our solutions offer more efficiency and increased accuracy and sensitivity for better yields in real time with minimal training.
From instrumentation and software to consumables and reagents to service and support, we are dedicated to providing you with end-to-end solutions that ease your everyday challenges of automation, throughput, service, and time to results.
Today’s advanced and increasingly diverse chromatography laboratories are facing new challenges on a daily basis – starting from raw materials right up to the finished product. Our comprehensive portfolio of analytical solutions is designed to give you the higher accuracy, sensitivity, and ease of use your laboratory demands for examining with confidence, the purity, composition, and performance of your compounds. What’s more, a range of complementary services is available to keep your laboratory up and running, meeting the stringent requirements of a variety of environments and working practices.
Trust the consumables engineered for your instruments.
Whatever your separation challenge, your choice of liquid chromatography (LC) column can make all the difference. Our Quasar portfolio of LC columns combined with the improved work? Workflow and usability of the LC 300 system allows you to achieve rugged and reproducible results. Now, with the purchase of an LC 300 system, you can pick out a Quasar LC column free of charge. Learn more below.
For labs looking to expand their analytical portfolio to include HPLC-ICP-MS, PerkinElmer's NexSAR HPLC-ICP-MS brings together the inert NexSAR speciation analysis ready HPLC system and the revolutionary NexION ICP-MS in a seamless platform, integrated using Clarity chromatography software.
This Preparing Your Laboratory document walks through the different laboratory requirements in preparation for the installation of a NexSAR Speciation Analysis Ready HPLC system.
Product Certificate for the NexSAR 200 Inert HPLC Pump
Product Certificate for the NexSAR Inert HPLC Solvent Manager
Product Certificate for the NexSAR Inert HPLC and Cooled Inert HPLC Autosamplers