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Acetonitrile, LC/MS Grade, ≥99.9% (4x4L)

High purity LC/MS Grade Acetonitrile, specifically optimized and tested for LC/MS suitability, ensures high-sensitivity analysis with minimal impurities and interferences.

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Our range of high purity LC/MS grade solvents, specifically optimized and tested for LC/MS suitability, ensure high-sensitivity analysis with minimal impurities and interferences. Designed for the most demanding UHPLC and MS applications, you can be assured of the following:


  • No LC/MS TIC signals higher than 50 ppb Reserpine (ESI+ mode) and 50 ppb 4-Nitrophenol (ESI– mode)
  • Very low metal concentration
  • Low particles (sub-micron filtered)
  • Packaged in amber glass bottles with Actual Lot Analysis printed on each label
  • QR codes on labels for quick access to SDS

Our solvents are extensively QC tested to ensure the highest purity and lot-to-lot consistency.

Testing Parameters Acetonitrile LC/MS Grade Specification
ESI+ mode (as reserpine) ≤ 50 ppb
ESI- mode (as 4-nitrophenol) ≤ 50 ppb
Assay (by GC) ≥ 99.9 %
Water ≤ 0.01 %
Color (APHA) ≤ 10
Titratable acid ≤ 0.008 mEq/g
Titratable base ≤ 0.0006 mEq/g
Fluorescence trace impurities

≤ 0.3 ppb at 450 nm emission
≤ 0.5 ppb at emission maximum of impurities

Maximum UV absorbance

λ: 195 nm  Amax: ≤ 0.15 Au
λ: 200 nm  Amax: ≤ 0.05 Au
λ: 205 nm  Amax: ≤ 0.04 Au
λ: 210 nm  Amax: ≤ 0.02 Au
λ: 220 nm  Amax: ≤ 0.01 Au
λ: 254 nm  Amax: ≤ 0.005 Au

LC gradient suitability/elution Test ≤ 0.5 mAU at 254 nm
≤ 2 mAU at 210 nm
Residue after evaporation ≤ 1 ppm
Trace metal impurities (ppb) ≤ 5-50 ppb (depending on element – 18 elements tested)


Format Liquid
Grade LC/MS
Material Acetonitrile
Product Group LC & LC/MS Solvents
Technology Type Liquid Chromatography/Mass Spectrometry
Volume 4x4L
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High-Quality HPLC and LC/MS Solvents Help Ensure the Best Results

Best-in-class HPLC, UHPLC, and LC/MS performance requires high-purity, high-performance solvents. See how our solvent testing parameters provide complete confidence in your results.

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