HS 2400 M Headspace Autosampler | PerkinElmer
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HS 2400 M Headspace Autosampler

By being completely integrated into the GC workflow, the HS 2400 M Headspace Sampler communicates directly with the PerkinElmer GC 2400 GC System. The integrated technology allows users to access live status information from the headspace sampler directly on the GC detachable touchscreen, in and outside the lab.

The intuitive interface combined with the PerkinElmer SimplicityChrom CDS Software address laboratories’ need for simplified software-controlled GC workflow, no matter the expertise of the user. Powered by the proprietary pressure-balance technology, the HS 2400 M Autosampler helps reducing significatively the challenges of sample contamination while maximizing lab operativity and productivity with information on the go, anytime you need to make a decision.

Part Number N6410000
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The HS 2400 M Headspace Autosampler utilizes an array of proven technologies to ensure it delivers outstanding precision for any application. The result is superior repeatability for every sample in every run.


  • Easily accessible information on the GC 2400 Platform touchscreen and browser interface
  • Support 10 and 20 ml vials
  • Up to 40 vials with a 12 position oven for overlapping thermostatting
  • PerkinElmer SimplicityChrom CDS Software
  • Waters Empower™ CDS Software control


Pressure-balanced time-based sampling avoids the use of multiport valves, minimizing the number of components that come into contact with the sample. Peak distortion from adsorption, limited repeatability, and dead volumes are virtually eliminated. Carryover is also avoided, allowing true precision without the need to run blanks to purge the system. In addition, pressure balanced sampling allows to use different injection volumes in the same sequence. An ideal support to expedite the method development process.

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Application Note

GC-FID: Analysis of Benzene in Compliance to United State Pharmacopeia (USP) Grade Carbomer 940

Polyacrylic acid, also known as Carbomer, is used extensively in formulations across many industries, including cosmetics, pharmaceuticals, and personal care. Carbomers are polymers of acrylic acid cross-linked with allyl ethers of pentaerythritol or sucrose forming white, lightweight polymers that ...

PDF 788 KB
GC-FID: Analysis of Residual Solvents and Monomers in Plastic

Different types of plastics are used for these diverse applications, but all plastic manufacturing has a few common raw material needs, including monomers and solvents. Plastic manufacturing workflows are designed to use all monomer input in the formation of the plastic polymer, and to remove all so ...

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GC-FID: Determination of Cetyl Alcohol and Aliphatic Alcohol Impurities According to USP

Cetyl alcohol, also known as palmityl alcohol or 1-hexadecanol, is a long-chain aliphatic alcohol that is a common additive in foods, cosmetics, personal care products (e.g., lotions and creams), and industrial fuels. To ensure cetyl alcohol quality, the United States Pharmacopoeia (USP) has outline ...

PDF 1013 KB
GC-FID: Fast and Accurate Analysis of Fatty Acid Methyl Esters (FAMEs) In Edible Oils and Food Products

The analysis of triacylglycerols by gas chromatography (GC) in their native state is challenging, largely due to their poor volatility and tnhermal decomposition in hot injector ports. To improve their properties for GC and to provide a comprehensive characterization of fatty acids, the esterified f ...

GC/MS: Optimized Semivolatile Organic Compounds (SVOC) Analysis in Compliance with EPA Method 8270E

For more than 40 years, the United States Environmental Protection Agency (EPA) has monitored semivolatile organic compounds (SVOC) in wastes, soils/sediments, and groundwater via its Method 8270. This method is extensive in scope, targeting chemicals found in petroleum/soot (e.g., polycyclic aromat ...

HS-GC-FID: Analysis of Residual Solvents According to USP 467

Organic solvents are commonly used in the production of active pharmaceutical ingredients (API) and pharmaceutical products. The solvents are used for varying purposes including as synthesis reaction media, in the separation and purification of API during synthesis, to enhance yield, to impart desir ...

HS-GC-FID: Analysis of Residual Solvents According to USP Chapter 467 Using PerkinElmer GC 2400 Platform and Waters Empower CDS Software

This application note shows the integration of the PerkinElmer GC 2400™ Platform in a Waters Empower CDS Software environment for the analysis of residual solvents Chapter USP 467. Results show improved productivity and lab time optimization. Instrument control and data analysis was managed by Water ...

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HS-GC-FID: VOC Analysis of Commercial Paint

When CASE chemicals like coatings and paints are formulated, pigments, binding agents, and additives are dissolved into a carrier solvent, often a volatile organic compound (VOC) or water. This solvent functions to lower the mixture’s viscosity, enabling it to coat a surface easily and evenly. Once ...

PDF 904 KB
HS-GC: Accurate Analysis of Methanol Content in B100 Biodiesel According to EN14110

Biofuels continue to be of key importance to the energy sector as more renewable fuel solutions are developed to contribute to global climate goals and resolve energy shortages. Fatty Acid Methyl Ester (FAME) Biodiesel (B100) is a key component for blending with fossil-fuel diesel in portions of up ...

PDF 824 KB


How to Enable Sustainable GC Lab Operations?

Sustainability strategies are being integrated into a growing number of businesses and their operations. Laboratories are no exception. Although the necessity to reduce the environmental impact of laboratory operations is recognized, it cannot be disengaged from the economic viability of labs. Rathe ...

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Simplifying the GC Laboratory for Improved Efficiency

Labs seek to increase the capacity of their equipment, improve turnaround times and maximize the sensitivity of their testing – without placing additional burden on their operators. Simplification is one of the strategies of Industry 4.0 for manufacturing processes. It can also be applied to laborat ...

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What Are the Key Features of a GC Smart Connected Lab?

Interest in the potential of smart technologies was high before the pandemic hit in 2020. That interest changed to a necessity when businesses were faced with the need for remote and automated operations in order to maintain business continuity. Businesses that have embraced smart operations are see ...

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The Smart Behind Separations – GC 2400 Platform Brochure

Every day, analytical laboratories are challenged with balancing high productivity with efficient operations. And with the growing trend of hybrid work models, gas chromatography operators seek remote access to their GC – whether they’re working in a different part of the lab or at a completely diff ...

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Product Note

Clearer Results with the MS 2400 SQ System Clarifi Detector

PerkinElmer MS 2400 SQ System is designed around the cutting-edge Clarifi Detector. Engineered using the latest electron multiplier technology, the Clarifi Detector provides superior sensitivity (signal-to-noise) and the longest operational lifetime. Ions are efficiently converted into an electronic ...

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Connected Into the GC Workflow – In or Outside the Lab

By being completely integrated into the PerkinElmer GC 2400™ Platform, the HS 2400 Headspace Sampler enables labs to perform automated accurate volatile analysis, thanks to user-intuitive software and wireless detachable touchscreen. Powered by the proprietary pressure-balance technology, the HS 240 ...

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Engineered for Fast GC Method Development and Routine Analysis

Supporting unparalleled sensitivity, pinpoint precision, and ultimate ease-of-use, the HS 2400™ Headspace Sampler pairs with most standard GC Systems and features patented pressure balance sampling technology that allows precise introduction of samples into the column without the use of a gas syring ...

PDF 725 KB
Smart, Simple and Sustainable GC for More Productivity – PerkinElmer GC 2400 System

The innovative PerkinElmer 2400 System allows customers to achieve unprecedented levels of efficiency. Designed to address the growing productivity and throughput needs of analytical laboratories, the GC 2400 System features a detachable touchscreen, so you can make decisions faster and be more prod ...

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Uptime and Sample Throughput with Easy to Change SMARTsource Technology

The PerkinElmer MS 2400™ SQ Detector comes standard with SMARTsource™ (Simplified Maintenance And Removal Technology), GC/MS source easy to remove, clean and reassemble – without the need for tools. A simple twist of the SMARTsource allows users to completely remove the ion source and lenses of the ...

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Regulatory Compliance Certification

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