Application Note

Lead and Strontium Isotope Ratio Analysis Using the NexION 5000 ICP-MS


Isotope ratio measurements are used in many application fields, such as nuclear, geological, geochronological dating, clinical, and others. Depending on the industry, there is interest in measuring natural, depleted, or enriched isotope ratios and exact abundances of all isotopes for the element(s) of interest.

This work demonstrates the ability of the NexION® 5000 Multi-Quadrupole ICP-MS to accurately measure isotope ratios and abundances. A unique way of removing spectral interferences combined with the Universal Cell’s ability to enhance sensitivity and control the reaction within the cell, the instrument’s stability and a very high duty cycle allow for high precision isotope ratios to be achieved without the need to use excessively long measurement times.