Histamine is a contaminant sometimes found in seafood when improperly handled. High levels of histamine in seafood are often associated with scombroid poisoning, a bacterially induced illness from spoiled fish. Scombroid poisoning triggers acute allergic response, vomiting, diarrhea, hypotension, rashes and hives. The international codex standard for fish includes histamine levels as indicators of decomposition, hygiene and handling. The MaxSignal® Histamine Enzymatic Assay provides a user-friendly protocol, no washing steps necessary; sensitive histamine detection; fast results; and less than 5% cross-reactivity with 14 other biogenic amines.