PerkinElmer

Microplastics in Food Chain

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Concern is growing about the impact of microplastics on the marine and freshwater ecosystem, and in particular the effect on the food chain. In addition to leaching harmful additives, microplastics generate a surface biofilm that concentrates organic pollutants such as pesticides and attracts potentially harmful bacteria. This biota is consumed by marine organisms with potentially harmful consequences for the organisms themselves, the food chain, and human health. Issues such as how microplastics affect reproduction, growth, and productivity of bio-organisms, and how changes in immune response can lead to increased susceptibility to infection, are critically important, as they can lead to disruption in the food chain. In terms of physical harm, there is evidence of tiny particles penetrating into tissue, or into the brain, causing behavioral changes. Such research demands cellular imaging and assay technologies, gene sequencing, and proteomic tools.

Typical applications include:

  • Biochemical and cellular assays for cellular stress and inflammation, oxidative stress, cytotoxicity, cell viability, and hormone analysis
  • Kinase assays, including extracellular signal-regulated kinase (ERK), p38 mitogen-activated protein kinase, and C-Jun N-terminal kinase (JNK) for reactive oxygen species (ROS) studies
  • High-content cellular imaging for cell invasion, uptake, and localization studies
  • Vectra® Polaris automated multispectral immunohistochemistry (IHC) tissue imaging applications for localization and analysis of tiny particles embedded within tissue and cells
  • inForm® software for recognition, characterization, and size calculation of microplastic particles in tissue
  • In vivo multispectral imaging for tracking infection and immune response in live fish and crustaceans
  • MicroCT imaging for particle localization in vivo
  • Sequencing of biofilm bacteria, including automated library preparation; automated nucleic acid extraction using chemagen magnetic bead technology; LabChip® microfluidic separation of DNA (versus agarose gels) for size QC prior to next-generation sequencing (NGS) applications; microfluidic separation for protein analysis (versus sodium dodecyl sulphate polyacrylamide gel electrophoresis [SDS-PAGE] techniques)
  • AlphaScreen® technology for study of protein-protein interaction
  • Oxidative stress via ERK, p38 kinase, and JNK analysis with AlphaScreen, AlphaLISA® (homogenous ELISA assays), and DELFIA® technologies
  • Next-generation sequencing of biofilm bacterial genomes with JANUS® G3R NGS Express Workstation, Sciclone® G3 NGS/NGSx Workstation, Zephyr® G3 NGS Workstation, chemagic 360 and chemagic Prepito® nucleic acid extraction systems, and NEXTflex family of library preparation kits (for whole genome sequencing, small ribose nucleic acid [RNA] sequencing, target enrichment, custom amplicon panels, and DNA isolation)
  • Nanoparticle analysis

You may also want to check:
Polymer Identification
Microplastics as a Habitat

For research use only. Not for use in diagnostic procedure.

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Narrow your results
Product Type
  • Consumables (1)
  • Instruments (18)
  • Reagents (6)
  • Software and Informatics (2)
Application
  • DNA/RNA Quantitation (1)
  • DNA/RNA Quantitation and QC (1)
  • Kinase (2)
  • Protein Analysis (2)
  • Protein Analysis & Detection (2)
Assay points(200-50,000)
  • 100 (1)
  • 10000 (2)
  • 500 (2)
  • 50000 (2)
Assay Target
  • ERK1/2 (2)
  • JNK1/2/3 (1)
  • JNK1/3 (1)
Assay Target Class
  • Phosphoprotein (3)
  • Protein (1)
Automation Compatible
  • Yes (9)
Depth
  • 49.0 cm (2)
  • 50.0 cm (1)
  • 585.0 mm (1)
  • 69.0 cm (1)
  • 711.0 mm (1)
  • 80.0 cm (1)
Detection Method
  • Absorbance (2)
  • Alpha (5)
  • Brightfield (1)
  • Fluorescence (4)
  • Fluorescence Intensity (1)
  • Fluorescence Polarization (1)
  • Image-based Cytometry (1)
  • Label-free (1)
  • Luminescence (2)
  • Time-Resolved Fluorescence (TRF) (2)
  • Transmission (2)
Experimental Type
  • In vitro (2)
Format
  • Microplates (4)
Imaging Modality
  • High Content (2)
  • microCT Imaging (2)
  • Optical Imaging (6)
Length
  • 51-100 (1)
Molecular Modification
  • Phosphorylation (1)
Product Brand Name
  • AlphaLISA SureFire Ultra (3)
  • AlphaScreen SureFire (1)
  • EnSight (1)
  • IVIS (6)
  • LabChip GX (1)
  • LabChip GXII (3)
  • LabChip® (1)
  • NexION (1)
  • Opera Phenix (1)
  • Operetta CLS (1)
  • Quantum (1)
  • Sciclone (1)
  • Vectra Polaris (1)
  • VICTOR Nivo (1)
  • Zephyr (1)
Sample Type
  • DNA / RNA (1)
  • Protein (1)
Target Species
  • Human (4)
Technology
  • ICP Mass Spectrometry (1)

"Microplastics in Food Chain" 1-27 of 27 Products and Services

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LabChip GX GXII Touch Product

LabChip GXII Touch Protein Characterization System

The LabChip® GXII Touch protein characterization system provides the complete solution for reproducible quantitation, molecular weight sizing and percent purity analysis of protein samples. Leveraging microfluidic electrophoretic separation technology, the LabChip® GXII Touch system enables rapid characterization with minimal sample preparation setup and sample input volume.
IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

IVIS Lumina III In Vivo Imaging System

The IVIS® Lumina Series III brings together years of leading optical imaging technologies into one easy to use and exquisitely sensitive bench-top system.
NexION 2000 ICP-MS

NexION 2000 ICP Mass Spectrometer

PerkinElmer’s NexION® 2000 is the most versatile ICP-MS on the market, featuring an array of unique technologies that combine to deliver the highest performance no matter what your analytical challenge. Discover the effortless versatility of an instrument that makes it easy to handle any sample matrix, any interference, and any particle size.

PerkinElmer received on April 11, 2018 the Application Award from LaborPraxis in the category Bio and Pharma Analysis for the NexION 2000 ICP-MS. We were awarded this prize during analytica 2018 in Munich, Germany, in acknowledgment of a new technique enabling users to quantify the amount of metal in an individual cell for the first time.
Zephyr G3 NGS Workstation

Zephyr® G3 NGS Workstation

The Zephyr® G3 NGS workstation is a benchtop liquid handler designed to automate the construction of 48 to 96 next generation sequencing (NGS) libraries per day. The simplified user-interface and integrated hardware maximize laboratory productivity while reducing variability resulting from manual pipetting.
LabChip GX GXII Touch Product

LabChip GX Touch Nucleic Acid Analyzer

DNA and RNA quantitation and sizing can be done in seconds using automated capillary electrophoresis separation. The LabChip® GX Touch nucleic acid analyzer’s microfluidic technology generates reproducible, high-resolution data and is optimal for
  • NGS library preparation (smear and fragment analysis) and quality control
  • RNA and DNA fragment analysis (including cell-free (cfDNA), FFPE, liquid biopsy, and PCR-free samples)
  • Quantitation and qualification for CRISPR fragment analysis
  • Agarose gel workflows
VICTOR Nivo Multimode Microplate Reader

VICTOR Nivo Multimode Microplate Reader

Building on our family of benchtop multimode plate readers, the VICTOR Nivo system packs all popular detection modes into the industry’s smallest multimode reader footprint. The perfect microplate reader for everyday biochemical and cell-based assays, it measures at any wavelength, with top and bottom reading of all technologies. Its software interface is easy to learn and use, and lets you control the instrument from almost any device – perfect for multiuser environments. Combine with our assays and reagents to get you started right away.
IVIS SpectrumCT 2D/3D Optical/CT In Vivo Imaging System

IVIS SpectrumCT In Vivo Imaging System

The IVIS® SpectumCT preclinical in vivo imaging system expands upon the versatility of the IVIS Spectrum by offering 2D and 3D imaging capabilities but includes integrated low-dose microCT ideal for longitudinal studies. The system provides researchers with greater insights into complex biological systems by enabling simultaneous molecular and anatomical non-invasive imaging in animal models.
chemagic-360-instrument

chemagic 360 Instrument

Nucleic Acid Extractor for Medium to High Throughput. Based on our patented chemagen magnetic bead technology the chemagic 360 instrument represents the ideal solution for nucleic acid isolation in a huge variety of research market segments including but not limited to Biobanking/Human Genetics, HLA Typing, Virus and Bacteria Detection.
Vectra Polaris with monitor

Vectra Polaris Automated Quantitative Pathology Imaging System

The Vectra® Polaris Automated Quantitative Pathology Imaging System integrates both multispectral imaging and automated slide scanning to better visualize, analyze, quantify, and phenotype immune cells in situ in FFPE tissue sections and TMAs.
IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

IVIS Lumina LT In Vivo Imaging System

The IVIS® Lumina LT Series III pre-clinical in vivo imaging system offers the industries most sensitive benchtop platform at an entry level price.
EnSight multimode plate-reader

EnSight Multimode Plate Reader

The EnSight multimode plate reader combines labeled & image-based cytometry technologies in a single benchtop platform. Imaging & online data analysis is fast: a 384-well plate can be imaged in less than 5 mins. The system’s modular design, combined with workflow-based Kaleido data acquisition & analysis software, gives a truly versatile plate reader that gets users productive quickly.
Sciclone-G3-NGSx-Workstation

Sciclone® G3 NGS and NGSx Workstation

The Sciclone® G3 NGS and NGSx workstations area complete benchtop solution for the automated construction of up to or greater than 96 libraries per day.

Next generation sequencing (NGS) technologies are enabling science at unprecedented rates. As the cost of sequencing declines, throughput continues to increase and the number of applications for which sequencing data can be used is expanding. The Sciclone® G3 NGS and NGSx liquid handling workstation was designed for high throughput, walkaway NGS sample preparation. The deck design and intuitive interface virtually eliminate cross contamination and user error. These liquid handlers simplify the construction of up to or greater than 96 libraries per day.

Operetta CLS High Content Analysis Instrument

Operetta CLS High-Content Analysis System

Uncover deep biological understanding in your everyday assays and innovative applications using the Operetta CLS high-content analysis system. Featuring a unique combination of technologies, the system delivers all the speed, sensitivity and resolution you need to reveal fine sub-cellular details. And with our simple, powerful Harmony 4.5 software, Operetta CLS lets you find even subtle phenotypic changes.
IVIS Lumina XRMS 2D Optical Imaging System with Integrated X-ray

IVIS Lumina XRMS In Vivo Imaging System

Industry leading Fluorescence, Bioluminescence and X-Ray Imaging - All-In-One benchtop instrument! The IVIS® Lumina XRMS (x-ray multi-species optical imaging system) adds to the versatility of the IVIS Lumina XR by offering the flexibility to image large animals up to 500 grams with precise optical and X-Ray overlay.

Opera Phenix High-Content Screening System

The Opera Phenix High Content Screening System is the premier confocal solution for today's most demanding high content applications. Drawing on over a decade of experience with the industry-leading Opera® High Content Screening System, the Opera Phenix is designed for high-throughput, phenotypic screening and assays involving complex disease models, such as live cells, primary cells and microtissues.
IVIS SpectrumBL High Throughput Optical Imaging System

IVIS Spectrum In Vivo Imaging System

The IVIS® Spectrum in vivo imaging system combines 2D optical and 3D optical tomography in one platform. The system uses leading optical technology for preclinical imaging research and development ideal for non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.
IVIS SpectrumBL High Throughput Optical Imaging System

IVIS SpectrumBL High-Throughput In Vivo Optical Imaging System

The IVIS® SpectrumBL is an advanced high-throughput 2D and 3D optical imaging system designed to improve quantitative outcomes of bioluminescent, chemiluminescent and Cerenkov in vivo imaging.
Quantum GX microCT Imaging System

Quantum GX microCT Imaging System

The Quantum GX microCT system has been replaced by the Quantum GX2 microCT imaging system. Please contact your local representative for further information, or visit the Quantum GX2 product page (Part Number - CLS149276).
SureFire principle

AlphaScreen SureFire JNK 1-3 (p-Thr183;Tyr185) Assay Kit

The AlphaScreen® SureFire® p-JNK1/3 (Thr183/Tyr185) assay is a sandwich immunoassay for quantitative detection of phospho-JNK1/3 (phosphorylated on Thr183/Tyr185) in cellular lysates using Alpha Technology. Please note that an AlphaScreen Protein A kit, which contains the Alpha Beads necessary to run this assay, needs to be purchased separately in addition to the AlphaScreen SureFire kit.
Price Range : 1493.00 USD - 16100.00 USD
AlphaLISA SureFire Ultra kits

AlphaLISA SureFire Ultra Total ERK 1/2 Assay Kit

The AlphaLISA® SureFire® Ultra™ Total ERK 1/2 assay is a sandwich immunoassay for quantitative detection of ERK 1/2 (both phosphorylated and non-phosphorylated) in cellular lysates using Alpha Technology. This assay is intended to be used as a normalization for phosphorylation studies.
Price Range : 489.00 USD - 28400.00 USD
AlphaLISA SureFire Ultra kits

Phospho-JNK1/2/3 (Thr183/Tyr185) AlphaLISA SureFire Ultra Assay Kit

The AlphaLISA® SureFire® Ultra™ p-JNK1/2/3 (Thr183/Tyr185) HV (high volume) assay is a sandwich immunoassay for quantitative detection of phospho-JNK1/2/3 (phosphorylated on Thr183/Tyr185) in cellular lysates using Alpha no-wash technology.
Price Range : 489.00 USD - 28400.00 USD
AlphaLISA SureFire Ultra kits

AlphaLISA SureFire Ultra p-ERK1/2 (Thr202/Tyr204) Assay Kit

The AlphaLISA® SureFire® Ultra p-ERK 1/2 (Thr202/Tyr204) assay is a sandwich immunoassay for quantitative detection of phospho-ERK 1/2 (phosphorylated on Thr202/Tyr204 in ERK1, or Thr185/Tyr187 in ERK2) in cellular lysates using Alpha Technology.
Price Range : 489.00 USD - 28400.00 USD
DNA / RNA Reagent Kit

HT DNA NGS 3K Reagent Kit

The LabChip® NGS 3K reagent kit is a microfluidic assay used to measure total DNA and fragment size distribution for next generation sequencing (NGS) applications.
List Price : 595.00 USD
Protein Reagent Kit

Protein Express Assay Reagent Kit

Supports reagent use protocols for small or large batch sizes. Contains enough reagent for 4 primes to run large batch sizes up to 384 and 8 primes to run batch sizes of 48 or fewer.
List Price : 332.00 USD
LabChip Protein Microfluidics Chip

Protein Express Assay LabChip (LabChip GXII Touch 24)

The Protein Express LabChip is a fast and easy way to analyze protein and pico protein samples. 
List Price : 437.00 USD
inForm monitor

inForm Tissue Finder

inForm® Tissue Finder adds exceptional functionality to inForm Cell Analysis to automate the detection and segmentation of specific tissues through powerful patented pattern recognition algorithms. Automation provides consistent reproducible results and enables comparative studies of multiple markers and specimens, supporting researchers to make faster discoveries of the indicators of disease.
inForm monitor

inForm Cell Analysis

inForm® Cell Analysis enables quantitative per cell analysis of immunohistochemistry (IHC), immunofluorescence (IF), and RNA in-situ hybridization, enabling the separation of weak and spectrally overlapping markers, in single and multiplex assays.

"Microplastics in Food Chain" 1-27 of 27 Products and Services