1-29 of 29 Business Insights
Pesticides can adversely affect human health through the food we consume but can also leach into soil and groundwater and impact us through the environment. To keep up with a complex and constantly changing regulatory environment, your pesticide analysis solution needs to keep up with your burgeoning sample load.
In today’s budget-constrained, yet highly competitive laboratory environments, the samples you’re being asked to analyze – whether food, pharmaceutical, petrochemical, or environmental – are increasingly difficult. But for some labs, having a dedicated GC for every application isn’t an option. For them, a GC that can do it all isn’t just a nice-to have, it’s a necessity
For laboratories analyzing everything from air quality to flavors and fragrances, thermal desorption offers a faster, easier, more cost-efficient way to prepare samples for GC or GC/MS analysis. Ideal for the trace-level measurement of volatile organic compounds (VOCs)—as well as most semi-volatile chemicals—thermal desorption lets you avoid time-consuming, manual, solvent-based sample preparation in favor of a simple, streamlined, automated approach. It also delivers the added benefits of superior throughput and enhanced sensitivity.
The analysis of C2 to C12 volatile organic ozone-precursor compounds can present a serious technical challenge to the analytical chemist. Low concentrations in the atmosphere coupled with the need to monitor frequently to assess diurnal variations means that a preconcentration step of the sample before analysis by thermal desorption is required. While the samples can be collected in the field and returned to the laboratory, remote, field-based analysis is desired which allows reduced data turnaround time, minimizes sample collection hardware and permits the presence or absence of VOCs to be correlated with meteorological data. In the field, low-molecular-weight C2 VOCs can be trapped on solid adsorbents if those adsorbents are cryogenically cooled.
Although it was built for portability and speed, the low thermal mass (LTM) capillary GC provides equivalent chromatographic resolution and performance to a benchtop system. The miniature size is achieved by replacing a conventional convectively-heated column oven with a low thermal mass (LTM) column bundle with direct-contact electrical resistive heating. LTM GC uses a small diameter, metal capillary GC column, which is bundled with resistive heating and temperature-sensing wires that are braided Superior technology • Small diameter LTM capillary GC for high speed, high resolution separation of chemical analytes • Rapid temperature programming delivers analysis times of under three min. • Sensitive and selective mass-based detection of a wide range of chemicals • Easy to operate with a color touch-screen display and simple navigation buttons Figure 1. The Torion T-9 Low Thermal Mass Capillary GC is fast and operates reliably. Injection Port with Removable Liner LTM Capillary Column Bundle Cooling Fan Electronic Pressure Control GC Electronic Board together with insulator strands. This design provides for greater heating and cooling speeds and very low power consumption
BTEX are regulated toxic compounds while benzene is also an EPA target carcinogen. The investigation of these compounds, especially in drinking water at low levels, is critical to protect public health. This application note focuses on exceeding the current EPA detection limit requirement for BTEX while meeting and/or exceeding all other criteria in EPA method 524.2 for these analytes.
This application note will concentrate on the potency identification and quantification of THC and CBD in cannabis by Gas Chromatography. Other application notes will cover potency by HPLC, pesticide analysis and residual solvent analyses. Analysis of cannabis has taken on new importance in light of legalized marijuana in several states of the USA. Cannabis contains several different components classed as cannabinoids. Primary cannabinoids of interest are tetrahydrocannabinol (THC), cannabidiol (CBD) and cannabinol (CBN). Positive identification and quantification of the THC/CBD ratio is a primary objective in the analysis of cannabis. Cannabis is analyzed for several different purposes.
Liquid chromatography-tandem mass spectrometry (LC/MS/MS) has become the method of choice for pesticide The state of Oregon has issued regulatory limits for 59 pesticide residues in both cannabis flower and concentrates, while other states have come up with
Water polluted by herbicides leach and runoff can cause human health problems including cancer tumors, reproduction deformity, disruption of the endocrine system and DNA damage. This application presents a sensitive and robust liquid chromatography method to test nine widely used herbicides (Figure 1), using a 3 µm UHPLC column to achieve very high throughput at a low flow rate to reduce testing time and solvent consumption. The throughput is compared to that of a conventional C18 HPLC column. Method conditions and performance data including precision and linearity, are presented.
This method outlines the analysis of volatile organic compounds in a variety of solid waste matrices including various air sampling trapping media, ground and surface water, soils, and sediments among others. The method requires not only demonstration of laboratory sample preparation and handling competence but instrument performance as well. The study presented here demonstrates the PerkinElmer® Clarus® SQ 8 GC/MS with purge and trap sample introduction both meets and exceeds the performance criteria set out in method 8260C and describes the analytical results and instrumental methodology.
The synthesis of active pharmaceutical ingredients (API) may require multiple reaction steps that produce undesirable reaction byproducts or utilize various solvents that have to be removed from the finished product. These solvents and byproducts may be measured with headspace gas chromatography for those volatile residual organic solvents according to the USP chapter 467 method. Method USP 467 classifies residual solvents into three classes according to toxicity; class 1 solvents are to be avoided unless there is strong justification, class 2 solvents are those that should be limited due to toxicity concerns.
Chlorophenols are by-products of the drinking water purification process and are also widely used as wood preservatives, herbicides and pesticides. In this study, the derivatization and extraction happened in the headspace vials during the vial thermostatting step. The derivatization reaction is affected by temperature and time, therefore the thermostat time and oven temperature of the headspace sampler were investigated for optimum derivitization/extraction conditions.
This application note presents a fast and robust liquid chromatography method to simultaneously test nine widely used additives. Among the additives tested are: preservatives (benzoic acid, sorbic acid, dehydroacetic acid and methylparaben); artificial sweeteners (acesulfame potassium, saccharin and aspartame); flavoring agent (quinine); and a stimulant (caffeine).
This study describes the injection, separation, and identification of 16 drugs compunds in less than 10 minutes using portable gas chromatograph-toroidal ion trap mass spectrometry (PerkinElmer, Torion T-9 Portable GC/MS) combined with a coiled-wire-filament (CWF) sampling injector to provide an effective tool for onsite analysis of illicit drugs substances.
Ginseng has been used as an herbal medicine in Asia for over two thousand years for its purported various health benefits, including, antioxidant, anticarcinogenic, antiinflammatory, antihypertensive and anti-diabetic. The pharmacologically active compounds behind the claims of ginseng’s efficacy are ginsenosides; their underlying mechanism of action although not entirely elucidated appears to be similar to that of steroid hormones. There are a number of ginseng species, and each has its own set of ginsenosides.
Air pollution is a global concern. Ground-level ozone has become an increasingly important issue in developed nations, as the health effects of smog are more clearly understood. The monitoring of VOC ozone precursor compounds will continue to play a role in defining and reducing air pollution in developed and developing nations in the next decade. The data presented here shows the excellent results of improved separation via Elite-624Sil MS column with real world samples, simplified column connections to the Dean Switching device and trap with modernized triple bed trap with guard zone technologies.
This application describes an analytical method for the chromatographic separation and quantitative monitoring of seven primary cannabinoids, including THC and THC-A, in cannabis extracts by HPLC with PDA detection. Naturally occurring cannabinoids, the main biologically active component of the cannabis plant, form a complex group of closely related compounds, of which 113 are known and 70 are well described. Of these, the primary focus has been on ?9-tetrahydrocannabinol (THC), as the primary active ingredient due to its pharmacological and toxicological characteristics, upon which strict legal limits have been enforced.
In recent years there has been an increase in fatalities related to the use and consumption of opioids, a class of synthetically manufactured pain-relieving drugs similar to naturally derived opiates like morphine, opium, codeine, and heroin. This application demonstrates the use of the novel Custodion® Coiled Microextraction (CME) syringes and the Torion T-9 Portable GC/MS as a fast and easy to use screening tool for drugs of abuse and new psychoactive substances (NPS) in the field.
Volatile organic compounds (VOCs) are a series of compounds with boiling points from 50 to 250 degrees centigrade and are widely used as industrial chemicals/ solvents. Low concentrations of VOCs can have a significant impact on human health, as many are regarded as highly toxic, refractory and carcinogenic. The detection and determination of VOCs in the environment is of the upmost importance for both human and environmental health.
In this application, we describe a technique for the monitoring of six cannabinoids, including THC and CBD, in hemp seed oil by HPLC with PDA detection. Figure 1 shows the chemical structures for the six cannabinoids. In recent years, scientific knowledge regarding the composition and health benefits of edible hemp products has significantly increased. Hemp seed oil has been promoted as a good source of nutritious omega-6 and omega-3 polyunsaturated acids, and may be a cleaner, more sustainable alternative to fish oil.
This analysis focuses on the detection of trace level semi-volatile organic compounds in extracts from solid waste matrices, soils, air sampling media and water samples. The method lists over 200 compounds however a majority of laboratories target between 60 and 90 for most analyses. The study presented here demonstrates the PerkinElmer® Clarus® SQ 8 GC/MS, not only meets the method requirements but provides users flexibility to satisfy their individual productivity demands. An extended calibration range is presented as are the advantages of the Clarifi™ detector.
Optimized methods are needed for the analysis of toxic compounds in air to understand the impact to human health. People breathe approximately 20,000 liters of air a day so this concern is significant. EPA Method TO-171 is used to determine toxic compounds in air after they have been collected onto sorbent tubes. This application note demonstrates that the PerkinElmer TurboMatrix™ Thermal Desorber and the PerkinElmer Clarus® SQ 8 GC/MS will meet and exceed the criteria set forth in EPA method TO-17. Detailed instrument method parameters are presented, with precision, recovery, linearity and detection limit results.
Customer complaints of odors within a new car are rising with the increasing number of new car buyers. Although odors can be subjective, it is now well known that the new car smell is the result of chemicals emitted from the in-vehicle interior components such as the dashboard, interior panels, seat coverings, flooring materials, and so on. This application note describes a method for the automotive industry that provides a qualitative analysis and the olfactory character of each component using the TD-GC/MS-Olfactory Port.
This document is intended to provide the newcomer to headspace sampling with a concise summary of the theory and principles of this exciting technique. Enough information is included here for the user to understand the basic concepts and relationships in HS sampling to apply during method development and interpretation of data. Although emphasis is given to the PerkinElmer TurboMatrix HS systems, the document also covers alternative systems so that it should be useful to all potential users of HS systems.
PerkinElmer’s new desorption tube is now used on a routine basis and it is changing the way Pace and its customers conduct environmental testing. In fact, productivity and customer satisfaction at Pace Labs has significantly improved thanks to this single method approach. The benefits of the TO-17 thermal desorption tubes are that they use no solvent, rendering it a more environmentally friendly method.
The following is an interview with Lee Marotta, Senior Field Application Scientist at PerkinElmer, Inc. Lee has more than 20 years of experience in the environmental field supporting water, soil, and air applications and is a long-time advisor to the EPA. As our PerkinElmer resident expert, Lee talks about the new benzene testing standards at the fenceline of North American refineries as required by Method 325 A/B.
As petroleum and refining experts and suppliers, you are a vital asset to the nation. So why not focus on what you do best and allow a world-class leader in environmental analysis to handle the details on your Method 325 response? Because of Method 325’s complex requirements for continuous passive air sampling, ongoing laboratory analysis, and detailed reporting to establish a traceable audit trail, you can turn to PerkinElmer, a global leader for industrial solutions.
This study will demonstrate how the GC instrumental parameters are optimized so that VOCs, in addition to semi-volatile organic compounds (SVOCs), can be analyzed on the same instrumentation enabling enhanced throughput and laboratory efficiency. It will also discuss the number of samples required by each refinery depending on its size, in addition to the distribution of sampling sites around the refinery.
This study describes the recovery of compounds above the boiling point of naphthalene achieved by optimizing the thermal desorption chemistry for the determination of volatile organic compounds ranging from C3 to C26 in soil gas samples using Method TO-17. Figures of merit such as breakthrough, precision, linearity, and detection capability are presented, in addition to an evaluation of its real-world capability at sites with moderate diesel and semivolatile polynuclear aromatic hydrocarbon (up to pyrene) contamination, in the presence of high humidity. This research has provided a means to determine a more representative composition of soil gas.
1-50 of 91 Products & Services
Built to run hundreds of pesticides in one run, with the utmost sensitivity and efficiency, the QSight™ Pesticide Analyzer is the only instrument that provides 15% higher throughput than conventional systems.
This Refinery Gas Analyzer model supports hydrocarbon, by FID and light gases by TCD.
Some features for this specific model include: