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1-12 of 114 Products & Services

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  • Photo of Alpha CETSA 500 point kit

    BCL-2 Alpha CETSA Target Engagement Assay Kit

    Measure binding of small molecule drug candidates to target protein in a cellular environment with Alpha CETSA® target engagement assays. For use in combination with Pelago Bioscience's CETSA® (Cellular Thermal Shift Assay) technology, this kit provides a convenient no-wash assay for detection and quantitation of small molecule binding to BCL-2, and can be used in hit identification, hit confirmation, and lead optimization studies for increased confidence and better prediction early in the drug discovery process. Please note that a valid CETSA® subscription from Pelago Biosciences is required for use.
    Price Range : 3333.00 USD - 28900.00 USD
  • Photo of Alpha CETSA 500 point kit

    EGFR Alpha CETSA Target Engagement Assay Kit

    Measure binding of small molecule drug candidates to target protein in a cellular environment with Alpha CETSA® target engagement assays. For use in combination with Pelago Bioscience's CETSA® (Cellular Thermal Shift Assay) technology, this kit provides a convenient no-wash assay for detection and quantitation of small molecule binding to EGFR, and can be used in hit identification, hit confirmation, and lead optimization studies for increased confidence and better prediction early in the drug discovery process. Please note that a valid CETSA® subscription from Pelago Biosciences is required for use.
    Price Range : 2171.00 USD - 14400.00 USD
  • AlphaLISA immunoassay kits

    KIM-1 (human) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for human Kidney Injury Molecule 1 (KIM-1) enables the quantitative determination of human KIM-1 in buffered solution, urine, cell culture media, and cell lysates using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 759.00 USD - 14600.00 USD
  • AlphaLISA immunoassay kits

    CXCL13 (mouse) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for mouse CXCL13 enables the quantitative determination of mouse C-X-C Motif Chemokine Ligand 13 in serum and cell culture media using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 782.00 USD - 11600.00 USD
  • PerkinElmer

    Micro Conductive Tips

    We offer a wide array of disposable tips, consumables and accessories for the JANUS® Automated Workstation.
    List Price : 147.00 USD
  • LANCE Detection Kit

    IL-6 (mouse) LANCE Ultra TR-FRET Detection Kit

    The LANCE® Ultra Mouse IL-6 Detection Kit is designed for detection and quantitation of murine IL-6 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
    Price Range : 830.00 USD - 11100.00 USD
  • LANCE Detection Kit

    CXCL9/MIG (human) LANCE Ultra TR-FRET Detection Kit

    The LANCE® Ultra Human CXCL9/MIG Detection Kit is designed for detection and quantitation of human CXCL9/MIG in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
    Price Range : 830.00 USD - 11100.00 USD
  • AlphaLISA immunoassay kits

    CD276 (human) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for human CD276 enables the quantitative determination of human Cluster of Differentiation 276 (CD276, B7-H3) in serum, buffered solution, and cell culture media using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 782.00 USD - 15000.00 USD
  • AlphaLISA immunoassay kits

    N-cadherin (human) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for human N-cadherin enables the detection and quantitation of human N-Cadherin in tissue homogenates and cell lysates using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 478.00 USD - 10500.00 USD
  • Assay principle for LANCE TR-FRET binding assay

    CTLA4-CD86 AlphaLISA Binding Kit

    The AlphaLISA® CTLA-4/CD86 binding kit is designed for the detection of binding activity between human CTLA-4 and CD86, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.
    Price Range : 1876.00 USD - 11400.00 USD
  • AlphaLISA immunoassay kits

    FCGR2B/CD32b AlphaLISA Binding Kit

    This kit is designed for the detection of binding between FCGR2B (CD32b) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapeutics by using competitive binding.
    Price Range : 2213.00 USD - 11100.00 USD
  • Alpha Fc receptor bind

    FCGR3A/CD16a (176Val/V158) AlphaLISA Binding Kit

    This kit is designed for the detection of binding activity between human FCGR3A (176Val) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapetics by using competitive binding.
    Price Range : 725.00 USD - 11100.00 USD
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  • Application Note

    Phenotypic Analysis of Hypertrophy in Human iPSC-Derived Cardiomyocytes

    Learn how a phenotypic screening assay to study time-dependent effects of endothelin-1-induced hypertrophy was set up using human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes. Learn how: The Opera Phenix system has been applied in the field of neurodegenerative diseases. In this assay, the Opera Phenix system is 4 times faster than the previous Opera® system. Primary neuron morphology is analyzed in a straightforward approach using Harmony software. Careful assay optimization can increase throughput, and minimize the data burden, without compromising assay performance.

  • Application Note

    Imaging Bile Canaliculi in 3D Liver Microtissues using the Opera Phenix HCS System

    Analyzing transport of biliary metabolites is essential to predict pharmacokinetics and hepatotoxicity during drug development. A functional impairment of hepatobilary transporters, such as bile salt export pump (BSEP) and multidrug resistance-associated protein 2 (MRP-2), is strongly associated with an increased risk of cholestatic liver injury. Here, we describe a 3D high-content screening assay to study hepatobiliary transporter function in InSphero human liver microtissues. Confocal imaging and automated image analysis were used to quantify BSEP and MRP-2-mediated efflux of fluorescent substrates into bile canaliculi.