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DSC 8500

The DSC 8500 is a double-furnace DSC, featuring our second-generation HyperDSC technology. Now you can gain unlimited insight into the structure, properties and performance of your materials.

We stand firmly behind our products and now offer a 5 YEAR PARTS ONLY FURNACE WARRANTY* with new instruments.

*Not available in all regions. Terms and Conditions apply. Warranty is void if the product is misused.

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Overview

  • Extremely fast controlled scanning rates to 750ºC/min
  • In-situ ballistic cooling to 2100ºC/min, enabling experiments that mimic real-world processes
  • Extremely fast data readout rates (100 points/second) providing high data integrity
Typical applications for the DSC 8500:
  • Characterization of pharmaceutical materials
  • Polymorph characterization in pharmaceuticals
  • Process studies in pharmaceuticals
  • Process simulation in plastics

Specifications

21 CFR Part 11 Compatible Yes
Maximum Temperature 750 °C
Minimum Temperature -180 °C
Portable No
Technology Type Thermal Analysis
Warranty 1 year
Resources, Events & More
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Application Note

Better Characterization of Hot Melt Adhesives Using the Double Furnace DSC

Hot melt adhesives are a copolymer consisting of ethylene and vinyl acetate (VA). The end use properties of EVA copolymers, such as packaging films and hot melt adhesives, are very much dependent upon the level of the amorphous vinyl acetate component contained in the copolymer. The characterizat ...

PDF 1 MB
Characterization of Fats in Cookies Using Power Compensation DSC

The processing and handling behavior of food fats has been found to depend upon the solid-to-liquid fat ratio in the food sample. Many rheological or flow properties, and their resultant effect on the texture of the final product, stem from this fat ratio index. The Power Compensation or double furn ...

PDF 2 MB
Characterization of Polyketone Copolymer by High Speed DSC

The aliphatic polyketone copolymer (PK copolymer) is a perfectly alternating copolymer of ethylene and carbon monoxide. It exhibits many desirable engineering thermoplastic properties, such as a high tensile yield stress and an excellent impact performance. Its high degree of chemical resistance ...

PDF 525 KB
Confirming Polymorphic Purity with HyperDSC

Many materials have complex molecular structures that areable to exist in more than one crystalline form, a phenomenontermed polymorphism. Different forms may have differentproperties and, for pharmaceutical use, it is important tobe able to produce a pure and stable crystalline form of any material ...

PDF 335 KB
Detecting Weak Glass Transition (Tg) in Polymers by HyperDSC

Many polymers are semi-crystalline material. The percentage of crystallinity depends on many factors including chemical structure, interaction between polymer chains and processing conditions. One typical example is High Density Polyethylene (HDPE), a highly crystalline engineering thermoplastic. ...

PDF 475 KB
Detecting the Adulteration of Extra Virgin Olive Oil by Controlled Cooling DSC

Controlled cooling in the DSC represents a way to extract information from food products not normally accessible by other methods. Extra virgin olive oils have a distinct cooling profile that is different from lesser grades and apparently this profile is quite responsive to changes in composition ...

PDF 1 MB
Determination of Critical Cooling Rate for Hardening Aluminum Alloys using HyperDSC

When an aluminum alloy is solution annealed andafterwards cooled too slowly, an exothermal precipitationreaction occurs. With increasing cooling rate, theprecipitation heat decreases. Since the precipitation reaction is relatively fast, a fast cooling rate on the differential scanning calorimeter (D ...

PDF 1 MB
Differential Scanning Calorimetry Performance Comparison

Differential scanning calorimetry (DSC) is a commonly used technique for studying polymeric; pharmaceutical; and energetic; materials. When considering which type of DSC to use to perform a specified measurement one typically chooses either a Power Compensation, or heat flux design.

PDF 541 KB
Food Packaging Compendium

Need to ensure quality, safety and reliability of food packaging? This compendium of Application Notes will provide you with R&D and QA/QC insights from plastic food trays, to bags, films and canned goods. The compendium provides research data and experimental results for; mechanical durability ...

PDF 11 MB
High Resolution Characterization of Pharmaceutical Polymorphs Using Power Compensation DSC

Many pharmaceutical materials exhibit polymorphism, and depending upon the given processing conditions, the crystalline form may exist in two or more states. The existence of these polymorphic crystalline states is important for many pharmaceutical materials, as they can have a major effect upon ...

PDF 575 KB
HyperDSC for High Throughput Formulation Development

The concept of High-Throughput Design has gained more and more interest as a way to increase profitability and to decrease research costs. One technique that can increase the ability of a laboratory to evaluate formulations is HyperDSC™ or High Ramping Rate DSC. HyperDSC is the ability to quantitati ...

PDF 720 KB
HyperDSC – A Breakthrough Method for Materials Characterization

Increasing the sensitivity and throughput of Differential Scanning Calorimetry (DSC) analysis has always been a challenge for thermal analysts in research and development. DSC analysis becomes difficult for small sample sizes, high throughput applications, materials that may experience re-crystal ...

PDF 1 MB
Isothermal Crystallization Study for Quality Assurance

Therefore, it is a sensitive test and can be used to show the difference between various batches of material, which may show little difference under a conventional heating experiment. Batches with different crystallization behavior will lead to variation in the quality of the final processed product ...

PDF 666 KB
Isothermal Crystallization Study for Quality Assurance

Isothermal crystallization is a sensitive test and can be used to show the difference between various batches of material, which may show little difference under a conventional heating experiment. For polymer resin manufacture, it can be used for quality assurance purposes, the optimization of resin ...

PDF 672 KB
Measurement of Glass Transition Temperature (Tg) in Lyophilized Formulations

In designed formulations for lyophilized drugs, it is important to know the collapse temperature of the cake. If the collapse temperature is exceeded, the cake will collapse and the batch will be ruined. The collapse temperature is often associated with the glass transition temperature (Tg) of th ...

PDF 1 MB
Polymer Applications Compendium

Today’s plastics are some of the most used materials on a global volume basis. Broadly integrated into today’s industrial and commercial lifestyles, they make a major, irreplaceable contribution to virtually every product category.

In this compendium you will find a wide range of applicatio ...

PDF 57 MB
Polymer Crystallinity Studies by DSC - Raman Spectroscopy

DSC and Raman spectroscopy are both used to investigate crystallinity but in rather different ways. DSC can determine the degree of crystallinity very precisely and can also follow the kinetics of crystallization by measuring the associated enthalpy changes.

PDF 350 KB
Polymorphism in Acetaminophen Studied by Simultaneous DSC and Raman Spectroscopy

DSC and Raman spectroscopy are complementary techniques that are often applied to the same problems, principally to study phase transitions in solids. PerkinElmer’s state-of-the-art double-furnace DSC is heavily used in material characterization.

PDF 391 KB
Practical Food Applications of Differential Scanning Calorimetry (Dsc)

This note describes a number of important food applications utilising the PerkinElmer DSC demonstrating the versatility of the technique as a tool in the food industry.

PDF 765 KB
StepScan DSC for Obscured Transitions

StepScan DSC is a temperature modulated,DSC technique that operates in conjunction,with the Power Compensation Diamond,DSC from PerkinElmer. The approach,applies a series of short interval heating,and isothermal hold steps to cover the temperature range of interest. With the,StepScan™ DSC approach, ...

PDF 822 KB
Thermal Analysis Applications in the Semiconductor Packaging Industry

The assembly and packaging phase of semiconductor manufacturing requires failure analysis and quality control processes which are of critical importance to final product quality and performance. Analytical measurements like Thermal Analysis allows users to analyze the thermal behavior of epoxies ...

PDF 1 MB
UV-DSC Study on New Double Furnace DSC

The UV curing of resins is important in materials science. Direct energy measurement and true isothermal operation are essential to a successful UV curing experiment. Since the UV curing reaction is fast, a fast response DSC is needed to capture the process. The double-furnace power-controlled DSC 8 ...

PDF 934 KB

Article

Characterization of D-Mannitol by Thermal Ananlysis, FTIR, and Raman Spectroscopy

D-Mannitol is a common excipient used in the pharmaceutical formulation of tablets. It is often desirable to process the formula into an amorphous glassy state to improve some physical biological properties of the drug.

PDF 487 KB

Brochure

DSC Family Brochure

Truly comprehensive, our DSC portfolio of applications, instruments and services, combined with our expertise in materials characterization, can help you push the edge of science.

PDF 2 MB

Case Study

Renault F1® Team - Stronger and Safer with PerkinElmer Analysis

PerkinElmer has been helping Renault F1 Team's Enstone Technical Center with their analytical needs for nearly 30 years. PerkinElmer began by outfitting the team’s testing lab with the analytical instrumentation needed to conduct materials testing. Today, a dedicated PerkinElmer scientific laborator ...

PDF 503 KB

Ebook

Palm Oil Analysis. Complete lab solutions from upstream to downstream

Quality control-monitoring and testing are important in ensuring the quality of palm oil. The quality control parameters are used to judge the quality of palm oil products and it can be monitored and tested to ensure that the palm oil is not deliberately or accidentally adulterated.

PDF 11 MB

FAQ

Pyris Enhanced Security FAQ

The regulations of 21 CFR Part 11 cover overall system compliance and include administrative, procedural and technical elements. Software alone cannot be compliant without the development and implementation of the other elements. PerkinElmer’s Pyris™ Enhanced Security software for Thermal Analysi ...

PDF 187 KB

Guide

Differential Scanning Calorimetry (DSC) Frequently Asked Questions

The differential scanning calorimeter (DSC) is a fundamental tool in thermal analysis. It can be used in many industries - from pharmaceuticals to polymers and from nanomaterials to food products. The information these instruments generate is used to understand amorphous and crystalline behavior, ...

PDF 1 MB
Evolved Gas Analysis - Hyphenated Technology Guide

The needs for polymer, pharmaceutical, chemicals, food and beverage, and environmental analyses are constantly changing due to innovation demands and regulation changes.

Evolved Gas Analysis (EGA) solutions combine multiple analytical technologies to empower speed and advanced information a ...

PDF 3 MB

Poster

Advanced Solutions for Polymers and Plastics

This poster lays out our whole material characterization range for the analysis of polymers and plastics. Find ideal techniques and instruments at each stage in the polymer manufacturing process: Resin Development - Resin Manufacture - Compound Development - Compound Manufacture - Product Formi ...

PDF 2 MB
Advanced Solutions for Solar Cells

Download this poster for an all-in-one view of how PerkinElmer instrumentation can answer the analytical needs of the solar market. From R&D of nanomaterials and advanced materials to solar cell component testing including aging and defect analysis - our UV/Vis, DSC, TGA, FT-IR and ICP systems he ...

PDF 1 MB

Product Note

Polymer Recycling Package

Polymer and plastics recycling is a rapidly growing industry, fueled by the increasing consumption of goods and the associated increase in landfill waste. Not only does plastic recycling reduce environmental problems caused by polymeric waste accumulation, it will also lead to a decrease in oil c ...

PDF 2 MB
UV/DSC Study on New Double Furnace DSC

Product Note, Thermal, Differential Scanning Calorimetry, HyperDSC, UV, Visible, UV/Vis, UV Vis, DSC 8000, DSC 8500, 8000/8500

PDF 964 KB

Regulatory Compliance Certification

Product Certificate - DSC 8000/8500

Product Certificate for the DSC 8000/8500 with and without Autosampler

PDF 98 KB

Technical Note

DSC 8000 Equilibration

Modulated Temperature Differential Scanning Calorimetry (MTDSC) is a capability for determining from a single, multi-step DSC method both the specific heat capacity and the heat flow data drom a kinetically controlled process (e.g., reaction or crystallization). PerkinElmer provides this capability ...

PDF 1 MB
Modulated Temperature DSC and DSC 8500: A Step Up in Performance

Modulated Temperature Differential Scanning Calorimetry, MTDSC, Single and Multi-Step DSC Methods, StepScan, DSC 8500, DSC 8000, Modulated DSC, sinusoidal, Diamond DSC, Pyris 1, SmartScan

PDF 2 MB
New Design Improvements of the DSC 8000/8500 Double-Furnace Differential Scanning Calorimeter

A simple experiment is suggested to demonstrate the response time of a DSC and to show how much time is needed for equilibration.

PDF 659 KB
New Design Improvements of the DSC 8000/8500 Double-Furnace Differential Scanning Calorimeter

A calorimeter is a device that measures the heat exchange of a sample with its environment. Since heat is usually generated or consumed during a physical transition or chemical reaction; calorimetry is a universal tool to study such processes.

PDF 453 KB
The New Optima Family Computer-Controlled Solid-State RF Power Supply

High throughput is a common concern for manufacturing environments. Recently, it has grown in importance for today’s busy research and analytical laboratories as well. Automation can be key to increasing a laboratory’s capabilities while freeing an analyst’s time for other work.

PDF 1 MB
Thermal Cooling Accesories

Differential Scanning Calorimetry, DSC, Simultaneious Thermal Analyzers, STA, Thermomechanical Analyzers, TMA, Cooking Accessories, Chillers, Refridgerated Coolers, LN2 Systems, non-cfc, non-chlorofluorocarbon, liquid nitrogen, portable cooling device, cryofill.

PDF 483 KB