Iodinated Compounds

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Radiometric detection is considered the gold standard for many applications, from drug discovery and development to plant sciences. ¹²⁵I labeled compounds are useful in both basic research and drug discovery where they are used as tracers in radioimmunoassays (RIA) and ligands in binding studies. ¹²⁵I is particularly versatile as it emits both gamma and Auger electrons. This means that can be it counted either directly, without requiring scintillation, or by using a liquid scintillation counter. We offer a wide range of ¹²⁵I labeled compounds as well as customized services to label your unique compound.

We also provide customized services to ¹³¹I labeled your compound of interest.

For Research and investigative use only.

Products & Services (74)
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Products & Services (74)

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Drug Discovery & Development (72)

Therapeutic Area

Angiogenesis (8)
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Obesity (5)
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NEN Radiolabeled Ligands (72)

Detection Method

Radiometric (74)

Receptor Type

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Vasoactive Intestinal Peptide (2)
Vasopressin (2)

Radionuclide

¹²⁵I (74)

Label Position

Nominally Labeled (71)
Specifically Labeled (3)

Concentration

1.0 - 10 mCi/mL (1)
1.12 mCi/mL (1)
1.14 mCi/mL (1)
152 µCi/mL (1)
170.1 µCi/mL (1)
171 µCi/mL (1)
172.5 µCi/mL (1)
173.9 µCi/mL (1)
182 µCi/mL (2)
2.93 MBq/mL (1)
236 µCi (1)
3.06 MBq/mL (1)
3.22 MBq/mL (1)
33.7 µCi (1)
345 µCi/mL (3)
353 µCi/mL (1)
41.4 µCi/mL (2)
42.5 µCi/mL (1)
45.7 µCi/mL (1)
50 µCi/mL (1)
6.05 MBq/mL (1)
79.2 µCi/mL (2)
83.8 µCi/mL (1)
85.1 µCi/mL (1)
87.2 µCi/mL (1)
87.4 µCi/mL (1)
87.6 µCi/mL (1)
87.9 µCi/mL (1)
88.5 µCi/mL (1)
93.2 µCi/mL (1)
<1.0 µCi/mL (3)
<100 µCi/mL (1)

Volume

0-50 (8)
51-100 (1)
201-250 (1)

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1-25 of 74 Products & Services

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Recombinant Protein A, [¹²⁵I]-, 100µCi (3.7MBq)

NEX146L100UC

Recombinant Protein A, labeled with ¹²⁵I. I-125 labeled Protein A can be used as a general tracer to capture antibodies in radioimmunoassays (RIAs).

List Price : 1019.00 USD
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Neurokinin A, ([¹²⁵I]-Substance K

NEX252010UC , NEX252050UC

Neurokinin A (Substance K), labeled with ¹²⁵I. Neurokinin A is a member of the tachykinin family of neuropeptide neurotransmitters, and is an endogenous agonist for NK-2 receptors. NK-2 receptors are potential drug targets for depression.

Price Range : 899.00 USD - 2359.00 USD
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N-succinimidyl-3-(4-hydroxy-3-[¹²⁵I]iodophenyl)propionate, Bolton-Hunter Reagent

NEX120002MC , NEX120001MC , NEX120250UC

Bolton-Hunter reagent, monoiodinated. This product is used to iodinate proteins that do not contain tyrosine residues. Bolton-Hunter reagent is the N-hydroxysuccinimide ester of iodinated p-hydroxyphenylpropionic acid. The active ester acylates terminal amino groups with the iodinated p-hydxyphenylpropionic residue, effectively introducing radioactive iodine into proteins and peptides. A non-oxidative technique, it is less harsh to proteins than alternative labeling methods. An anhydrous benzene A charcoal trap is provided with each vial.

Price Range : 640.00 USD - 1748.00 USD
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CGRP (human), [¹²⁵I]

NEX354050UC , NEX354010UC

Calcitonin gene-related peptide (CGRP), labeled with ¹²⁵I. CGRP binds calcitonin receptors.

Price Range : 877.00 USD - 2125.00 USD
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IP-10 (human, recombinant), [¹²⁵I]-, Bolton-Hunter Labeled

NEX348005UC , NEX348025UC

Interferon gamma-induced protein 10 (IP-10; CXCL10), labeled with ¹²⁵I. IP-10 binds the chemokine CXCR3 receptor, and is secreted in response to IFN-γ.

Price Range : 818.00 USD - 1985.00 USD
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Thyroxine, ([¹²⁵I]-T4), Specific Activity: 135-165 µCi/µg

NEX111100UC , NEX111250UC , NEX111500UC

Thyroxine (T₄) labeled with ¹²⁵I. Thyroxine is a thyroid hormone that is responsible for regulation or metabolism. T₄ detection by radioimmunoassay is a common test of thyroid disease. This product is offered at three specific activities. Specific activity indicates how much radioactivity there is per molecule of thyroxine. Several of our ¹²⁵I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one ¹²⁵I labeling site is available, 4400 Ci/mmol if two labeling sites are available).

Price Range : 716.00 USD - 1998.00 USD
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PDGF [¹²⁵I] (human)

NEX433005UC , NEX433025UC

NEX433 [¹²⁵I]-PDGF BB homodimer has been shown to work in RIA and receptor studies, using CHO cell line transfected with human PDGF B receptor, and human artery smooth muscle cells.

Price Range : 1028.00 USD - 2314.00 USD
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α-Bungarotoxin, [¹²⁵I]-Tyr⁵⁴

NEX126250UC , NEX126500UC , NEX126050UC

α-bungarotoxin, labeled with ¹²⁵I on tyrosine residue 54. α-bungarotoxin is a snake venom neurotoxin that acts as an antagonist at nicotinic acetylcholine receptors (nAChRs). This product as offered at two specific activities. Specific activity indicates how much radioactivity there is per molecule of ligand. Several of our ¹²⁵I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one ¹²⁵I labeling site is available). This indicates that virtually every molecule of ligand provided in the stock vial is radiolabeled.

Price Range : 623.00 USD - 3032.00 USD
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Ghrelin (human), [His[¹²⁵I]]

NEX388010UC , NEX388025UC

Ghrelin, labeled with ¹²⁵I. Ghrelin is a peptide that regulates appetite and energy, and binds the ghrelin/growth hormone secretagogue receptor (GHS-R).

Price Range : 1485.00 USD - 2893.00 USD
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Endothelin-1 (human, porcine), [¹²⁵I]Tyr¹³

NEX259005UC , NEX259050UC , NEX259010UC

Endothelin-1 (ET-1), labeled with ¹²⁵I on the tyrosine 13 residue. Endoethlin-1 is a vasoconstrictor that acts as an endogenous agonist at endothelin receptors. Endothelin receptors are a class of GPCRs that are potential drug targets for hypertension and cancer.

Price Range : 1004.00 USD - 2761.00 USD
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Neurokinin B, [¹²⁵I]His, MePhe⁷

NEX285050UC , NEX285010UC

Neurokinin B (NKB), labeled with ¹²⁵I on the histidine residue. Neurokinin B is involved in ovarian cycle regulation, and binds neurokinin 3 receptor (NK3R; tachykinin receptor 3), a GPCR involved in vascular remodeling, angiogenesis, and cancer.

Price Range : 1077.00 USD - 2512.00 USD
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Recombinant Protein A, [¹²⁵I]

NEX146025UC , NEX146010UC

Recombinant Protein A, labeled with ¹²⁵I. I-125 labeled Protein A can be used as a general tracer to capture antibodies in radioimmunoassays (RIAs).

Price Range : 854.00 USD - 1382.00 USD
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Ornithine Vasotocin Analog, [¹²⁵I]-OVTA)

NEX254050UC , NEX254010UC

Ornithine Vasotocin Analog (OVTA), labeled with ¹²⁵I. OVTA binds oxytocin receptors, a hormone receptor involved in pregnancy, milk production, stress, social memory, and bonding.

Price Range : 1208.00 USD - 2448.00 USD
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Thyroxine, ([¹²⁵I]-T4), 5700 µCi/µg

NEX111X500UC , NEX111X100UC

Thyroxine (T₄) labeled with ¹²⁵I. Thyroxine is a thyroid hormone that is responsible for regulation or metabolism. T₄ detection by radioimmunoassay is a common test of thyroid disease. This product is offered at three specific activities. Specific activity indicates how much radioactivity there is per molecule of thyroxine. Several of our ¹²⁵I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one ¹²⁵I labeling site is available, 4400 Ci/mmol if two labeling sites are available).

Price Range : 992.00 USD - 2914.00 USD
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Epibatidine, ([¹²⁵I]-IPH), [¹²⁵I]

NEX358050UC , NEX358010UC

Epibatidine, labeled with ¹²⁵I. Epibatidine has analgesic activities, has been shown to function as an agonist at nicotinic acetylcholine receptors, and has been shown to bind muscarinic and serotonin 5-HT₃ receptors.

Price Range : 2000.00 USD - 4384.00 USD
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Triiodothyronine, ([¹²⁵I]-T₃)

NEX110500UC , NEX110H250UC , NEX110250UC , NEX110H500UC , NEX110100UC , NEX110H100UC , NEX110X100UC , NEX110X250UC , NEX110X500UC

Triiodothyronine (T₃) labeled with ¹²⁵I. Triiodothyronine is a thyroid hormone that affects growth and development, body temperature, and heart rate. T₃ detection by radioimmunoassay is a common test of thyroid gland function. This product is offered at three specific activities. Specific activity indicates how much radioactivity there is per molecule of ligand. Several of our ¹²⁵I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one ¹²⁵I labeling site is available, 4400 Ci/mmol if two labeling sites are available).

Price Range : 742.00 USD - 2765.00 USD
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α-Dendrotoxin [¹²⁵I]

NEX434005UC , NEX434010UC

NEX434 [¹²⁵I]- α-Dendrotoxinsare a class of neurotoxins produced by mamba snakes that block particular subtypes of voltage-gated potassium channels in neurons. Dendrotoxins enhance the release of acetylcholine at neuromuscular junctions.

Price Range : 1159.00 USD - 1846.00 USD
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2'-Deoxycytidine-5'-triphosphate, 5-[¹²⁵I] iodo-, Tetraammonium Salt

NEX074001MC , NEX074100UC

Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that is used whenever DNA is synthesized, such as in the polymerase chain reaction. ¹²⁵I dCTP may be used to produce cDNA transcripts of viral or mRNA.

Price Range : 1206.00 USD - 3017.00 USD
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MCP-1,[¹²⁵I]- labeled, Bolton-Hunter Labeled

NEX332025UC , NEX332005UC

Monocyte chemoattractant protein 1 (MCP-1; CCL2), labeled with ¹²⁵I. MCP-1 is a cytokine released by tumor cells that binds chemokine receptor 2 (CCR2).

Price Range : 807.00 USD - 1901.00 USD
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Peptide YY, (Porcine), ([¹²⁵I]-PYY)

NEX240050UC , NEX240010UC

Peptide YY (peptide tyrosine tyrosine), labeled with ¹²⁵I. Peptide YY acts as a neuropeptide Y receptor Y2 agonist, is released in response to feeding, and is associated with appetite saiety.

Price Range : 1108.00 USD - 2558.00 USD
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LH-RH, [¹²⁵I]-[D-Trp⁶]

NEX365010UC , NEX365050UC

Luteinizing Hormone Releasing Hormone (LHRH), labeled with ¹²⁵I. LHRH binds LHRH receptors, and is a drug target for cancer therapy.

Price Range : 1151.00 USD - 3071.00 USD
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Bombesin (6-14), D-Tyr6[¹²⁵I]

NEX377010UC , NEX377025UC

Bombesin (6-14), labeled with ¹²⁵I. Bombesin binds and activates bombesin receptors BBR1, BBR2, and BBR3, and is a tumor marker for lung cancer, gastric cancer, pancreative cancer, and neuroblastoma.

Price Range : 1396.00 USD - 2624.00 USD
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α-Bungarotoxin, [¹²⁵I]-Tyr⁵⁴-, High Specific Activity

NEX126H050UC , NEX126H250UC

α-bungarotoxin, labeled with ¹²⁵I on tyrosine residue 54. α-bungarotoxin is a snake venom neurotoxin that acts as an antagonist at nicotinic acetylcholine receptors (nAChRs). This product as offered at two specific activities. Specific activity indicates how much radioactivity there is per molecule of ligand. Several of our ¹²⁵I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one ¹²⁵I labeling site is available). This indicates that virtually every molecule of ligand provided in the stock vial is radiolabeled.

Price Range : 708.00 USD - 2231.00 USD
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Iodoaminopotentidine, [¹²⁵I]

NEX431025UC , NEX431010UC

NEX431 [¹²⁵I]-Aminopotentidine has been shown to work in receptor binding and autoradiography and is an antagonist for histamine (H2) receptors.

Price Range : 941.00 USD - 2124.00 USD
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Bombesin, [¹²⁵I]Tyr⁴

NEX258050UC , NEX258010UC

Bombesin, labeled with ¹²⁵I on the tyrosine 4 residue. Bombesin is an endogenous agonist for bombesin receptors (BB1, BB2, BB3), and is also a tumor marker for certain cancers.

Price Range : 1146.00 USD - 2448.00 USD

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