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Neutrophil Elastase (NE) is a protease secreted by neutrophils. Neutrophils the first responders of the innate immune system and play a crucial role in fighting invading pathogens. Thought to be indiscriminate killers, research shows neutrophils are implicated in chronic inflammatory diseases and contribute to injury repair.
Better understand neutrophilic response in vivo with Neutrophil Elastase 680 FAST NIR fluorescent probe. Neutrophil Elastase 680 probe can detect NE post-degranulation or netosis from activated neutrophils.