1-1 of 1 Resource Library
Ion channels are one of the major classes of therapeutic targets due to the central role they play in numerous physiological processes. PerkinElmer’s ValiScreen® cell lines provide an effective means to study compound effects on recombinant ion channels or recombinant G protein-coupled receptors in a well-characterized cell line. In this technical brief we illustrate a membrane depolarization assay performed with the EnVision® Multilabel Plate Reader, describe the optimization of important cell culture parameters, and define the EnVision optical and dispenser settings used to perform this assay.
1-1 of 1 Products & Services
Stable, recombinant ValiScreen® cell line expressing Potassium voltage-gated channel member 3 (KV1.3, KCNA3), human recombinant in CHO-DUKX host cells.