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Ca2+-activated photoproteins are important tools for analyzing all aspects of Ca2+-mediated signal transduction processes in mammalian cells. One of their characteristics is the immediate photon release (flash luminescence) upon Ca2+ binding to the coelenterazine photoprotein complex, which makes this system extremely useful for studying rapid receptor-ligand interactions or fast acting ion channels involving Ca2+ mobilization.
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Stable, recombinant PhotoScreen® cell line expressing a photoprotein and the Transient receptor potential TRPA1, human recombinant in HEK293 host cells.