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XenoLight RediJect 2-DeoxyGlucosone (DG)-750 is a fluorescent,probe for in vivo targeting of tumors that typically exhibit elevated,glucose uptake rate in comparison to surrounding tissues. To achieve,maximum glucose targeting and enhanced tumor uptake, the probe,has been designed to contain four 2-DG molecules per dye molecule.,As indicated in Figure 1, RediJect 2-DG-750 probe showed specific,accumulation to LL-2 tumors shortly after delivery. In addition, specific,tumor labeling with the RediJect 2-DG-750 probe has also been,demonstrated with Breast (MDA-MB-231) Prostate (PC-3M) and Lung,(NCI-H460) tumors, further validating the utility of this probe as a generic fluorescence reagent for in vivo tumor targeting.
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