1-25 of 244 Products & Services
Maximum inertness and packed with wool gives optimum sample dispersion. Surface provides inertness over wide sample pH range. Wool can be adsorptive if fibers are broken.
Quartz Liner for Splitless Operation (ships with instrument) - Standard injector liner.
Universal liner for general purpose analyses. Surface provides inertness over a wide sample pH range. Wool can be adsorptive if fibers are broken.
Deactivated Glass Liner for Splitless Operation (with wool) - Good for analyses of trace samples.
Quartz Liner for Splitless operation - Excellent liner for low volume analyses.
This 3-slot quartz organics torch is used with Optima™ 7300 V ICP-OES series instruments.
Glass Liner for Splitless Operation - Universal liner for general purpose analyses.
Quartz Liner for Split Operation - Good for large volume injection samples.
Maximum inertness gives optimum sample dispersion. Deactivated surface provides minimal bleed and inertness over a wide sample pH range.
1-25 of 135 Resource Library
The opportunity to leverage big data in the complex business environments such as in Pharma has expanded from analyzing experimental data to predictive modeling, clinical trial monitoring and into business operation data management and analysis.
In this case study, learn how a multinational pharmaceutical company has expanded data analytics capabilities for 5000 users, starting with a small group of R&D, to early clinical trials, clinical trial development, safety, regulatory, and more.
The International Conference on Harmonization Guideline for Elemental Impurities Q3D (ICH Q3D) has established maximum permitted daily exposure limits for elemental impurities in pharmaceutical products. In combination with the U.S. Pharmacopeia’s (USP) Chapters <232> and <233> on elemental impurities, they redefined how the pharmaceutical and related supply-chain industries will measure, document, and comply with strict new standards to limit the presence of elemental impurities in drug products.
PerkinElmer provides the tools and processes you need to take control of impurities testing for both drug substances and drug products, providing proven, reliable technology for the identification and quantification of elemental impurities and the accurate measurement of residual solvents in accordance with strict regulatory guidelines.
Download this brochure to learn more.
As the importance of sustainable energy production increases, so too does the global commitment to using fuels from renewable biological sources. Biodiesel is one such renewable fuel. Consisting of fatty acids of methyl esters (FAME), it is produced from plant crops by transesterification – a reaction in which natural triglycerides are cleaved and reacted with methanol, producing glycerol and FAME. Rapeseed, soy, sunflower, palm and jatropha are just part of the range of feedstocks used globally in the production of biodiesel.
Like all botanicals and plants found in nature, cannabis also contains terpenes, which are the aromatic oils that give rise to the distinctive flavors and aromas found in cannabis varieties. There have been up to 140 different types of terpenes reported in cannabis, but multiple studies suggest that approximately 17 are the most common and can be used for examining their chemotype. The diverse palate of cannabis terpenes is impressive enough, but arguably their most fascinating characteristic is their ability to interact synergistically with other compounds in the plant, like cannabinoids. In the past few decades, a significant amount of work has been performed to understand the ‘entourage effect’, which scientists refer to as synergistic interaction between terpenes and cannabinoids in the human body. This effect is believed to magnify the therapeutic benefits of the plant’s individual components - so that the medicinal impact of the whole plant is greater than the sum of its parts quantifying which terpenes are present is an important aspect of understanding the unique effects of cannabis for both medicinal and recreational users. The PerkinElmer HS-GC/MS solution for the determination of terpenes is fast and robust providing the laboratory with greater sample throughput, instrument uptime, essentially a maintenance free system, and enhanced profits. Additionally, this procedure is a turnkey solution; therefore, all acquisition and processing methods and standard operating procedures (SOP) will be provided upon installation of the system. To further validate the performance of this method for the industry, The Emerald Test Proficiency Test (PT) for Potency was conducted. The Emerald Test™ is an Inter-Laboratory Comparison and Proficiency Test (ILC/PT) program for cannabis testing labs. The results from the PT inter-laboratory samples passed; therefore, the method meets inter-laboratory reproducibility and accuracy.
The polymer industry is made up of a diverse set of players, all facing similar challenges. Better characterization of materials and derivatives in the polymer value chain is vital to understand their thermal properties and suitability for use in a variety of applications. Faster product development, ensuring quality control, and reducing costs to stay ahead of the competition demands enhanced material characterization capabilities from a trusted partner. Our lineup of advanced solutions for thermogravimetric analysis (TGA) are designed to help you in:
Although considered pharmacologically inert, pharmaceutical excipients have been shown to interact with active drug substances to affect the safety and efficacy of drug products.Therefore, there is an increasing awareness of the necessity to understanding interactions between excipients and the active pharmaceutical ingredient (API) in finished dosage forms.
The analysis of all incoming pharmaceuticalraw materials is a key part of 21CFR compliance (section 211.84). It is therefore important to have a high-throughput method by which raw materials may be analysed in a loading bay or warehouse,while also preventing sample exposure.
With its great importance, milk is available in several different forms: fresh, boxed (ultraheat treated), powdered, and evaporated. The most commonly consumed form varies globally, being dependent on factors such as geography, culture, and climate. For milk producers, internal quality control and the possibility of external monitoring provide strong incentives for the ability to quickly, accurately, and easily monitor nutrients in their products.
This work demonstrates the ability of the Avio® 220 Max hybrid simultaneous ICP-OES to reliably and effectively analyze a variety of milk samples for an array of elements over a wide range of concentrations.
This study will demonstrate how the GC instrumental parameters are optimized so that VOCs, in addition to semi-volatile organic compounds (SVOCs), can be analyzed on the same instrumentation enabling enhanced throughput and laboratory efficiency. It will also discuss the number of samples required by each refinery depending on its size, in addition to the distribution of sampling sites around the refinery.
Title 21 of the Code of Federal Regulations (CFR) is the section of the United States government Rules and Regulations document that deals with the Food and Drug Administration (FDA). Chapter 1, Part 11 of this Section applies to records in electronic form and to the criteria under which the FDA will consider electronic records and signatures "to be trustworthy, reliable, and generally equivalent to paper records and handwritten signatures on paper".
The purpose of this document is to describe the relevant portions of the 21 CFR Part 11 regulations, and to explain their implementation using PerkinElmer's TotalChrom Client/Server software.
Knowing the protein concentration is commonly required in studies of protein biochemistry and molecular biology. A direct method of measuring protein concentration is to determine the absorbance spectrum at 280 nm. With this UV based approach, it enables scientists to rapidly determine the concentration of protein with a procedure that is simple and nondestructive, does not need special reagents or standard curves, and consumes very little sample.
In this study, learn why the VICTOR® Nivo™ multimode plate reader is an ideal instrument for UV/Vis analysis of proteins with a µDrop™ Plate. This combination provides robust and fast read-out of a single sample or up to 16 reads at once.
The objective of this study is to demonstrate the application of an analytical technique that integrates thermal analysis with gas chromatography and mass spectroscopy to identify and quantify toxic compounds emitted during the burning of electronics waste at different oxidizing conditions. The study simulates open burning practices that often accompany undeveloped e-waste recycling operations, and to provide information about exposure risks to these from emissions.
Considering the ever-rising cost, scope and complexity of clinical development, life science companies, contract research organizations (CROs), regulatory agencies and industry organizations are striving to find cost-effective ways of conducting on-site monitoring as this is the most costly aspect of running clinical trials.
The most significant approach to emerge in the last decade for a more efficient, cost-saving way to improve clinical trial monitoring is risk-based monitoring (RBM). This approach has been widely encouraged by regulatory agencies and is gathering momentum in adoption by sponsors and CROs. Proponents of RBM projects believe that the investment in this approach will return an overall reduction in monitoring expense by 15 to 20 percent. This paper discusses RBM as a high-value use case that can be enhanced by a robust clinical data aggregation and analytics solution.
The use of cannabis concentrates and CBD products (edibles, topicals, vape products, etc.) has increased in popularity as new regulation has been passed legalizing medicinal and recreational use in a number of states and provinces. Testing to ensure that pesticide and mycotoxin levels in cannabis products are below regulatory levels is critical, however, the cannabis concentrate matrix presents many analytical challenges including higher sample matrix effects and an increased concentration of cannabinoids in the sample.
In this application note, an LC/MS/MS method for the analysis of 66 pesticides (including hydrophobic and chlorinated pesticides typically analyzed by GC/MS/MS) and five mycotoxins in a cannabis concentrate matrix is presented. Utilizing a QSight® 420 LC/MS/MS instrument with dual APCI and ESI sources, the analysis yielded excellent recoveries and detection limits below those specified by the state of California cannabis regulations.
An improperly lubricated engine may suffer from excessive heat, wear and noise, and will often fail if the issue is not resolved. Upon adding a lubricant fluid to an engine, the very operation of that engine begins to impact the functionality of the oil. An example of this the degradation of lubricanting oil by the presence of fuel contaminants such as gasoline, diesel and biodiesel.
Oil testing facilities such as Caterpillar typically run hundreds of thousands of samples each year, thus requiring a fast and robust method for analysing diluents. This study outlines the principles and technology for such a fast and robust GC method.
Syngistix™ for ICP software boasts a number of smart features designed to optimize your workflows and the performance of the Avio® Max ICP-OES instruments – from initial instrument setup to final results – for consistent, efficient, reliable operation. Flexible and easy to use, these smart features offer immediate benefits whether you’re running the instruments, running the laboratory, or running the business.
Download this product note to learn more about Syngistix for ICP software.
Customer complaints of odors within a new car are rising with the increasing number of new car buyers. Although odors can be subjective, it is now well known that the new car smell is the result of chemicals emitted from the in-vehicle interior components such as the dashboard, interior panels, seat coverings, flooring materials, and so on. This application note describes a method for the automotive industry that provides a qualitative analysis and the olfactory character of each component using the TD-GC/MS-Olfactory Port.
PerkinElmer NetPlus™ is a cloud solution, it allows 24/7 access to results and instrument configuration. Analysis results are synchronized from the instruments to a server, providing access to registered users through a website.
Plastic bags are widely used in food packaging due to cost and flexibility, for example breakfast items such as hot steamed buns, oil cake and soybean milk are typically packaged in plastic. Leftovers, supermarket cooked food and even beer, are also packaged with plastic bags. Plastic packaging is very convenient but plasticizers and other additives dissolve and migrate into food during processing, heating and packaging, which can result in food contamination and permanent damage to human health and the environment.
This application note demonstrates a method for the determination of 16 phthalates (PAEs) and 16 polycyclic aromatic hydrocarbons (PAHs) leaching from plastic bags using the PerkinElmer Clarus® SQ 8 GC/MS with electron ionization (EI) source. The method is based on the Chinese National Standards GB 31604.1-2015, GB 31604.30-2016 and GB 5009.265-2016. 1-3 Toluene is used as a solvent to extract the target compounds from the food simulants.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus that causes COVID-19, the respiratory illness responsible for the COVID-19 pandemic. Studies have shown that patients infected with SARS-CoV-2 with cardiovascular comorbidities are more susceptible to severe infection and thus the case fatality rate in these patients rises. To further understand the pathology of SARS-CoV-2 in cardiomyocytes, a team of researchers from the University of Cambridge in the UK, have developed a screening platform using human embryonic stem cell-derived cardiomyocytes (hESC-CMs).
Thallium is considered one of the most toxic heavy metals and a cumulative poison that can cause adverse health effects and degenerative changes in many organs. The main threat to humans is through occupational exposure and environmental contamination.
Industry’s use of thallium is widespread, and leaching from ore processing operations is the major source of elevated thallium concentrations in water. Due to thallium’s potential to cause adverse health effects in exposed people, a number of regulations and guidelines have been established by agencies around the world.
Graphite furnace atomic absorption spectrometry (GFAAS) has proven to be a well-established testing technique but is challenged with meeting the low detection limit requirements of the regulations by direct analysis, so the pre-concentration procedure is often needed. In this work, a PerkinElmer PinAAcle® 900H GFAA spectrometer combined with Syngistix™ for AA software were used to develop an accurate and reliable sample enrichment method for the determination of ultra-trace level thallium in water.
Pharmacovigilance is concerned with identifying the hazards associated with pharmaceutical products and minimizing the risk of harm to patients. These programs have become increasingly complex, time-intensive, and expensive undertakings. Product sponsors are seeking ways to streamline the process, leveraging the use of technology to make pharmacovigilance activities more efficient and cost-effective.
PerkinElmer's pharmacovigilance solutions provide a new way to work with pharmacovigilance data, find insights, and drive operational efficiency. With connectors to source systems - such as Oracle's Argus® and Aris Global's Arisg® - all data can be integrated, allowing for the dynamic and interactive receipt of information and a faster way to view and comprehend safety information, reducing preparation time for safety team reviews from days to minutes.
Fuel cells offer cleaner and more-efficient energy than the internal-combustion engine. Many types of fuel cells are now available based on the electrolyte used, including polymer electrolyte membrane fuel cells (PEMFC), direct methanol fuel cells (DMFC), solid oxide fuel cells (SOFC), molten carbonate fuel cells (MCFC) and alkaline fuel cells (AFC). Each has its own electrolyte, cathode and anode as well as fuel type, typically operates in different temperature ranges and caters to different applications - among these, the polymer electrolyte membrane fuel cell is the most widely used.
During the manufacturing of polymer electrolyte membrane fuel cells, one of the most important parts is the membrane electrode assembly (MEA). One method to make an MEA is to print the catalyst containing ink over the gas diffusion layers - for example, carbon cloth. This application note describes how thermogravimetric analysis (TGA) can be used to check the ink formulation for quality control purposes and also to study the heat-treatment process of carbon cloth.
When mining for precious metals, ores are extracted from the ground and subjected to various sample preparation procedures in order to remove the metals of interest. A commonly used procedure to isolate metals from the ore is fire-assay, which leaves a matrix-free “button” of the metal. This work focuses on the analysis of precious metals in simulated digested precious metal buttons, and demonstrates the ability of the PinAAcle™ 500 Flame AA spectrometer to accurately measure low-level gold, palladium, platinum, copper, and silver in matrices which result from the fire-assay preparation of ore samples.