1-7 of 7 Products & Services
This accessory allows the analysis of rabbit species in the Quantum line of microCT instruments.
1-5 of 5 Business Insights
There is a growing body of evidence showing that there are significant differences between some nanomaterials and their non-nanoscale counterparts. What those differences portend raises many new questions about their potential to cause harm to human health and the environment.
X-ray CT imaging is commonly used for skeletal imaging as bones are densely mineralized tissues with excellent x-ray attenuation properties. In contrast, soft, less dense tissues often prove to be challenging to image due to their lack of sufficient tissue density. Soft tissues such as muscle, blood vessels and internal organs share similar x-ray attenuation characteristics and are not distinguishable under typical CT settings. In order to introduce density that would improve soft tissue contrast, several contrast agents have been developed for use in clinical and preclinical settings. This application note outlines the use of iodine and nanoparticle-based contrast agents for imaging soft tissues and vasculature in various organs using the Quantum GX to gain further insights into disease and therapeutic response.
From the start of our busy days to the end, electricity is the life blood that keeps us going. We cook, heat, clean, light, work, communicate and are entertained all driven by electricity. The most common modes of generation are hydro, nuclear geothermal or fossil fuel powered. There is a clear need throughout the world to develop clean renewable sustainable sources of power to support growing economies and reduce our carbon footprint.
Osteoarthritis (OA) is the most common form of arthritis and affects a considerable portion of the elderly population. In the U.S., it is estimated that more than 630 million people worldwide have this chronic condition, generally in the knees. OA occurs when the cartilage that cushions the ends of bones within the joints gradually deteriorates, causing synovitis and joint deformation.
The goal of OA research is to identify new therapeutic strategies that could prevent, reduce, halt progression, or repair the existing damage to the joint. Non-invasive in vivo imaging such as microCT is the standard modality for bone research due to its ability to obtain high-resolution images at an x-ray dose low enough as not to harm the animal. This makes microCT ideal for monitoring disease progression and response to treatments in the same animal over time. However, microCT data visualization and analysis can be cumbersome and time consuming. In this application note, we compared standard microCT software and advanced bone software to investigate bone erosion in an OA rat model.
The purpose of this primer is to provide some basic information about engineered nanomaterials so that you will be better informed, understand the new ‘jargon’ and appreciate some of the potential new applications of these materials. In addition, understanding the wide range and types of measurements needed to characterize these nanomaterials along with what solutions PerkinElmer has to support customers working in this field are outlined.