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Olopatadine hydrochloride is an antihistamine used to treat itching and redness in the eyes due to allergies. It is commonly available over the counter in several forms such as eye drops and as a nasal spray. Olopatadine was used in 1996 and 2002 to treat allergic conjunctivitis. In 2017, it was the 290th most prescribed medication in the United States, with more than one million prescriptions.
This application brief describes the use of a PerkinElmer Quasar™ C8 (150 x 4.6 mm, 5 µm) column in accordance with the official olopatadine hydrochloride USP monograph.
Meloxicam is a common pharmaceutical drug used to treat pain resulting from various musculoskeletal conditions such as osteoarthritis. It belongs to a class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs) which are effective in relieving pain and reducing inflammation, although they are known to exhibit problematic side effects such as stomach ulcers, headaches and drowsiness. Meloxicam acts by suppressing the synthesis of prostaglandins, which are the main cause of an inflammatory response. This results in analgesic effects and reduced inflammation. Meloxicam is a commonly prescribed drug with over 22.5 million prescriptions in 2018.
This application brief describes the use of a Quasar C18 column to analyze meloxicam using a method based on the Indian Pharmacopeia (I.P).
Venlafaxine is an antidepressant which belongs to a group of medicines called serotonin and norepinephrine reuptake inhibitors (SNRIs). This group of medicines is used to treat depression and other conditions such as anxiety. It is thought that people who are depressed and/or anxious have lower levels of serotonin and noradrenaline in the brain and venlafaxine should improve your mood and energy level and may help restore your interest in daily living.
Venlafaxine is on the World Health Organization’s (WHO) list of essential medicines, which serves as a model of the safest and most effective medications needed by a health system. This application brief describes the use of a PerkinElmer Quasar™ C8 (250 x 4.6 mm, 5 µm) column in accordance with the official venlafaxine hydrochloride USP monograph.