Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications.
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For laboratory use only. This product is intended for animal research only and not for use in humans.
VivoTag®-S 750 Fluorochrome (5mg) available in 5 mg quantity. VivoTag-S 750 is an amine-reactive near-infrared fluorochrome for coupling via a N-Hydroxysuccinimide (NHS)-ester linkage to peptides, small molecules, proteins, antibodies or macromolecules.
| Fluorescent Agent Type | Labeling |
|---|---|
| Optical Imaging Classification | Fluorescence Imaging |
| Product Brand Name | VivoTag |
| Quantity in a Package Amount | 1.0 Units |
| Shipping Condition | Blue Ice |
| Unit Size | 5 mg |
| Wave Length | 750 nm |
N-Hydroxysuccinimide (NHS)-ester labeling reagents, such as VivoTag®-S reagents, are commonly used for labeling proteins. The NHS ester moiety reacts with amino groups at pH 7-9 to form stable amide bonds. Lysines within proteins, including antibodies, are available as targets for this chemical conjugation.,Protein labeling efficiency may vary depending upon the type of protein labeled, so different conjugation ratios may need to be attempted to attain success. For Near Infrared (NIR) fluorophore conjugation, ratios of fluorophore to protein of 4:1 have been seen to generate effective imaging agents. Not all antibodies or proteins (independent of target specificity) make good imaging agents, due to long half-lives and/or excessive accumulation in non-target sites.
VivoTag-S® 750 is an amine reactive (NHS Ester) near-infrared (NIR) fluorochrome for labeling biomolecules for in vivo imaging applications.
