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Vasopressin (Linear), V-1A Antagonist (Phenylacetyl1, 0-Me-D-Tyr2, [125I-Arg6]-),10µCi

Vasopressin (linear), labeled with 125I. Linear vasopressin acts as an antagonist at vasopressin receptor 1A (V1AR).

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Unit Size
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NEX310010UC
10 µCi
964.00 USD
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NEX310050UC
50 µCi
2140.00 USD
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Detail Information

We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, PerkinElmer has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX310:

  1. Hammock, E.A., Levitt, P. (2012), Modulation of parvalbumin interneuron number by developmentally transient neocortical vasopressin receptor 1a (V1aR). Neuroscience, 222: 20-28.
  2. Phelps, S. M. and Young, L. J. (2003), Extraordinary diversity in vasopressin (V1a) receptor distributions among wild prairie voles (Microtus ochrogaster): Patterns of variation and covariation. J. Comp. Neurol., 466: 564–576.

Specifications

Detection Method Radiometric
Fresh Lot Days Second Monday of each month
Label Position Nominally Labeled
Molecular Weight 1274.0
Product Brand Name NEN Radiolabeled Ligands
Radioisotope I-125
Radionuclide 125I
Receptor Type Vasopressin
Shipping Condition Ambient
Special Ordering Information This is a radioactive product - shipping address must have a license to receive radioactive materials.
Therapeutic Area Cardiovascular
Unit Size 10 µCi