For research use only. Not for use in diagnostic procedures.
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twinlite™ is a dispense-and-read ultra-high sensitivity dual luciferase reporter gene assay system for the quantitation of Firefly and Renilla luciferase expression in mammalian cells. twinlite was designed to provide maximum signal intensity for assays requiring the utmost sensitivity, and is suitable for use in a tube or 96- and 384-well microplate format. twinlite is ideal for:
As with all members of our Lites suite of luciferase detection reagents, twinlite offers superior performance in an easy-to-use format, providing the following benefits:
|Experimental Type||In vitro|
|Product Brand Name||twinlite|
|Unit Size||1,000 assay points (96-well) / 4,000 assay points (384-well)|
Over these last few decades there has been a growing trend in drug discovery to use cellular systems and functional assays, in addition to biochemical assays, for the characterization of new potential therapeutics. The ability to study the interaction between a candidate drug and its target within the context of a whole, intact cell allows for more physiologically relevant data to be obtained. However, such assays are more complex than traditional biochemical assays as such facts as membrane permeability, cellular metabolism, cell variability, additional binding partners, and signal transduction must be considered.
To help you navigate the complexities in designing cell-based assays, we have gathered insights collected over the years and compiled them to provide you with elements to consider when setting up your cell-based assays. After all, any assay, biochemical or cell-based, is only as good as its design.