Quasar™ C18 LC columns, based on ultra high purity silica and manufactured to tight specification, provides high efficiency separations and excellent peak shape for a wide range of compounds. Our methodology to yield high surface coverage enhances the pH stability and extends the working range. If data integrity and high productivity are top priorities for your lab, then this column can support your needs for any application.
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|Inner Diameter||4.6 mm|
|Particle Size||5.0 µm|
|Product Brand Name||Quasar|
Metformin belongs to a class of drugs known as biguanides and contains the active ingredient metformin hydrochloride. Metformin oral tablets are used, in combination with diet and exercise, to treat high blood glucose levels in patients with type 2 diabetes mellitus. Tablets are often used as monotherapy, or in combination with other anti-diabetic agents or insulin.
This application brief describes the use of a Quasar C18 column for the analysis of metformin hydrochloride RS in accordance with Dissolution Test 3 in the United States Pharmacopoeia (USP) monograph for metformin hydrochloride tablets.
Retinol, one of the main forms of vitamin A, is regularly used in the treatment and protection of skin. By inducing the biosynthesis of collagen and promoting skin cell production, retinol helps to reduce the signs of early UV-induced skin aging. Retinol is also an anti-oxidant, allowing it to neutralize free radicals that may damage healthy skin cells. HPLC with UV detection is commonly used to assess and quantify retinol in a variety of samples.3 This application brief describes the use of a Quasar C18 column for the rapid analysis of retinol.