The Quasar AQ Plus phase, with its proprietary end capping and bonding, can provide alternative selectivity to a standard C18 phase and aid retention of polar compounds. This phase can offer improved separations with polar, acidic, basic and phenolic compounds. Quasar AQ Plus LC columns benefit from no phase collapse, even in 100 % aqueous mobile phase conditions, allowing robust analysis.
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|Inner Diameter||4.6 mm|
|Particle Size||3.0 µm|
In recent years there has been an increase in interest regarding 'AQ' columns due to their ability to retain polar analytes reproducibly under high aqueous conditions and with no phase collapse as a traditional C18 column would exhibit. There are two general approaches to the bonded phase chemistry of AQ columns. The first is to employ a polar or hydrophilic end-capping. The second method is to incorporate polar-embedded groups within the alkyl chains. These two methods provide a high degree of polar character to the final alkyl bonded phase, allowing full interaction with the alkyl chains upon wetting the silica surface with water. Additionally, the added polar functionality introduces a secondary separation mechanism (dipole-dipole interactions) to facilitate alternative selectivity for polar compounds. This application brief describes the use of Quasar™ C18, AQ and AQ Plus columns for the analysis of polar compounds, outlining the benefits of stationary phases offering alternative selectivity.
Whether you’re testing food, water, or pharmaceuticals, success often depends on getting back to basics. So whatever your separation challenge, your choice of liquid chromatography (LC) column can make all the difference. Our Quasar portfolio of LC columns allows you to achieve rugged and reproducible results – batch to batch and column to column – with an all-encompassing, flexible solution that meets the diverse, changing needs of analysis. Ultrapure silica-based Quasar columns deliver a comprehensive range of chemistries, together with state-of-the art, optimized bonding technology to give you a versatile, high-performing analytical solution for your increasingly complex samples. For flexibility, we provide a wide range of column sizes, including shorter columns packed with smaller particle sizes for shorter run times and better productivity. Plus, our scalable columns facilitate easy method transfer between HPLC and UHPLCtechnology platforms – and the smaller particle sizes means optimized sensitivity for those applications. Whatever your separation need, we have a chemistry or dimension to fill it.
Our wide range of column sizes has its benefits, including:• Longevity to withstand highthroughput environments• High-efficiency separations to facilitate trace-level analysis• Good resolution and peak shapes for more effective compound separation• Analysis of increasing polar and complex analytes.
Whether you need high-performance liquid chromatography (HPLC) or ultra-high performance liquid chromatography (UHPLC), with our versatile LC 300 solutions you can count on the right technology for the work you do. The LC 300 systems provide robust, trouble-free operation and are perfect for routine analysis and more demanding applications, giving you the highest sensitivity and resolution, as well as faster results.