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Quantum GX2 microCT Imaging System

Image beyond bone – into oncology, cardiovascular and pulmonary diseases, and much more, with the Quantum GX2 microCT imaging system. With the Quantum GX2, flexibility is key. Combining the ability to perform high speed, low dose scans, ideal for longitudinal studies, across multiple species (mice, rats, rabbits) with high resolution ex vivo scanning, the Quantum GX2 microCT imaging system offers the flexibility and performance you need to not just image, but further understand your disease models.

Part Number CLS149276
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Overview

Quantum GX2 microCT是真正的多物种临床前成像系统, 同时满足长时程活体动物成像和高分辨率离体样本成像。成像仓直径达到 163mm, 可以放置整只兔子并进行活体成像,而18mm 视野成像可以进行离体样本高分辨率成像。并且 Quantum GX2 能够与PerkinElmer 三维光学成像系统联用,形成多模式成像。自动骨分析软件(AccuCT), Quantum GX2 microCT 成像系统提供最大的灵活度 ,不管您的研究是肿瘤、血管疾病、骨科或者肺部疾病, Quantum GX2 都能满足您的需求。

主要特点

  • 高分辨率 (2.3μm)
  • 快速成像 (3.9 sec)
  • 低辐射剂量,适合活体长时程成像
  • 四个可选视野 (FOVs) – 18, 36, 72, 和86 mm
  • 多物种成像 (斑马鱼/小鼠/大鼠/豚鼠/兔)
  • 两相呼吸门控和心跳门控
  • 与功能模块光学信号 (IVIS ®和 FMT®)无缝对接

Quantum GX2 microCT 成像 与PerkinElmer其他活体成像模式 (光学 和 PET)结合,更深刻的在活体水平理解疾病进展和治疗效果 。

Specifications

Height 1450.0 mm
Imaging Modality microCT Imaging
Product Brand Name Quantum
Width 980.0 mm
Resources, Events & More
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Application Note

Contrast-enhanced Imaging of Vasculature and Soft Tissues Using the Quantum GX MicroCT System

X-ray CT imaging is commonly used for skeletal imaging as bones are densely mineralized tissues with excellent x-ray attenuation properties. In contrast, soft, less dense tissues often prove to be challenging to image due to their lack of sufficient tissue density. Soft tissues such as muscle, blood vessels and internal organs share similar x-ray attenuation characteristics and are not distinguishable under typical CT settings. In order to introduce density that would improve soft tissue contrast, several contrast agents have been developed for use in clinical and preclinical settings. This application note outlines the use of iodine and nanoparticle-based contrast agents for imaging soft tissues and vasculature in various organs using the Quantum GX to gain further insights into disease and therapeutic response.

PDF 10 MB
MicroCT Investigation of Bone Erosion and Deformation in an Osteoarthritic Rat Model

Osteoarthritis (OA) is the most common form of arthritis and affects a considerable portion of the elderly population. In the U.S., it is estimated that more than 630 million people worldwide have this chronic condition, generally in the knees. OA occurs when the cartilage that cushions the ends of bones within the joints gradually deteriorates, causing synovitis and joint deformation.

The goal of OA research is to identify new therapeutic strategies that could prevent, reduce, halt progression, or repair the existing damage to the joint. Non-invasive in vivo imaging such as microCT is the standard modality for bone research due to its ability to obtain high-resolution images at an x-ray dose low enough as not to harm the animal. This makes microCT ideal for monitoring disease progression and response to treatments in the same animal over time. However, microCT data visualization and analysis can be cumbersome and time consuming. In this application note, we compared standard microCT software and advanced bone software to investigate bone erosion in an OA rat model.

PDF 1 MB

Article

Editorial: MicroCT in Experimental Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension (PAH) is a life-threatening disease that affects the arteries in the lungs and the right side of the heart. Small animal models are often used in experimental PAH research due to their similarities to human cardiovascular physiology. MRI and microPET are established tools in evaluating RV function and physiology but both can present certain challenges including complex acquisition techniques, high imaging costs and accessibility. Conversely, microCT offers superior resolution, rapid data acquisition, and ease-of-use. Read this editorial and article published in the December issue of Circulation on how researchers report on the first quantitative assessment of RV and left ventricular systolic and diastolic volumes and function in an experimental model of PAH using the Quantum GX2 microCT imaging system.

PDF 52 KB

Brochure

3D Multimodality Imaging: See disease in all its dimensions

It’s simple: More information means more understanding,For today’s researchers in oncology, infectious diseases, inflammation, neuroscience, stem cells,and other disciplines, there’s an increasing need for in vivo imaging that enables you to visualize,multiple events simultaneously and to extract the maximum amount of information from each,subject – leading to greater biological understanding.,Multimodal imaging enables a better understanding of disease biology. By utilizing in vivo,optimized bioluminescent and fluorescent agents and radioactive probes, researchers can,measure depth, volume, concentration, and metabolic activity, providing a wealth of information,for untangling the mysteries of disease.,Coregistration allows researchers to overlay images from multiple imaging modalities, providing,more comprehensive insight into the molecular and anatomical features of a model subject.,For example, optical imaging data can be used to identify and quantify tumor burden at,the molecular level and, when integrated with microCT, provides a quantitative 3D view of,anatomical and functional readouts.,At PerkinElmer, we’ve developed industry leading imaging technology for preclinical research.,Our technology integrates 3D optical and PET modalities with microCT to provide a better,understanding of disease. And that means better monitoring of disease progression, earlier,detection of treatment efficacy, and deeper understanding of metabolic changes that take place,throughout disease development.

PDF 2 MB

Ebook

In Vivo Imaging Solutions eBook

Researchers trust our in vivo imaging solutions to give them reliable, calibrated data that reveals pathway characterization and therapeutic efficacies for a broad range of indications. Our reagents, instruments, and applications support have helped hundreds of research projects over the years. And our hard-earned expertise makes us a trusted provider of pre-clinical imaging solutions— with more than 9,000 peer reviewed articles as proof.

PDF 4 MB

Flyer

Product Note

Quantum GX2 microCT Imaging System

Product Note - Quantum GX microCT imaging system

PDF 2 MB

Regulatory Compliance Certification

Software Downloads

Video Article

White Paper

The Role of In Vivo Imaging in Drug Discovery and Development

The primary goal of preclinical imaging is to improve the odds of clinical success and reduce drug discovery and development time and costs. Advances in non-invasive in vivo imaging techniques have raised the use of animal models in drug discovery and development to a new level by enabling quick and efficient drug screening and evaluation. Read this White Paper to learn how preclinical in vivo imaging helps to ensure that smart choices are made by providing Go/No-Go decisions and de-risking drug candidates early on, significantly reducing time to the clinic and lowering costs all while maximizing biological understanding.

PDF 748 KB