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QSight Triple Quad 420

Ideal for analyzing food, cannabis, and environmental samples, our robust and reliable QSight® triple quad systems consistently deliver the throughput and productivity you need in your analytical testing lab. Now we’ve added the premier model to our QSight family: the high performance 400 series. This ready-to-implement solution has the highest sensitivity and throughput the industry has ever seen and the capability to test for the most challenging, complex samples, including cannabis.

Part Number
Model Name
BC003844
QSight 420 LC/MS/MS
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BC003382
QSight 220 LC/MS/MS
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BC003383
QSight 210 LC/MS/MS
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BC003265
QSight 110 LC/MS/MS
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Overview

Future proof your lab with the flagship QSight triple quad 400 series. This powerful LC/MS/MS system is engineered to deliver exponentially better sensitivity that commercial testing labs, global food manufacturers and exporters, and highly regulated cannabis labs need to meet their most stringent requirements – today and tomorrow.

  • Highest sensitivity to meet the most demanding regulations
  • Easy-to-use with ready to implement methods – just set and forget
  • Patented flow-based technology that enables up to 15% more productivity StayClean Source, self-cleaning design for maximum sensitivity and exceptional uptime
  • Laminar Flow Ion Guide for highly efficient field-free transmission, providing virtually no maintenance requirements
  • Dual Source technology gives you the capability to set ESI or APCI modes, with two independent probes for true multiplexing
  • Modular Simplicity 3Q software to acquire, quantify, and report with flexible data viewing options and powerful remote diagnostics.

Specifications

Model Name QSight 420 LC/MS/MS
Resources, Events & More
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Application Note

A Fully Validated Method for Determination of Twelve Mycotoxins in Various Food Matrices

Mycotoxins are toxic secondary metabolites produced by various fungal species growing in foods and animal feeds. To minimize risk and protect consumers, mycotoxin levels in foods and/or feeds have been regulated by agencies in many countries around the world. A number of analytical methods for ...

PDF 3 MB
A Multiclass Multiresidue Method for Analysis of Veterinary Drugs in Chicken by UHPLC/MS/MS

Veterinary drugs are used in animal production to treat diseases, prevent infection and protect growth of animals, which helps provide quality marketplace. However the uncontrolled use may cause heavy human disease so regulatory agencies around the world have established maximum residue levels (M ...

PDF 1 MB
A Single Cannabis Method to Meet California Pesticide and Mycotoxin Residues Regulatory Requirements

Testing for the levels of pesticide and mycotoxins in cannabis is important to ensure consumer safety and quality control. In this work, the PerkinElmer application development team analyzed all 66 pesticides (including very hydrophobic and chlorinated pesticides typically analyzed by GC-MS/MS) and ...

PDF 2 MB
Analysis of Acrylamide in Potato Chips by Isotopically Standard Addition UHPLC-MS/MS

Acrylamide is a probable carcinogen organic compound that is found in some foods that are cooked at elevated temperatures. It’s origins are due to the condensation of the amino acid asparagine and glucose as part of Maillard reaction. In 2002, Acrylamide was found to be present in french fries an ...

PDF 1 MB
Analysis of Aflatoxins by UHPLC

Aflatoxin B1 is considered to be the most genotoxic of the mycotoxins, and, when ingested by cows, is converted to aflatoxin M1 which has been shown to cause liver cancer in certain animals.

PDF 1 MB
Analysis of Low PPT Levels of Estrogens in Serum without Derivatization Using QSight 420 UHPLC/MS/MS System

Estrogens are steroid hormones derived from cholesterol. They are crucial for the development of female secondary sex characteristics and reproductive functions, and are also important for many other non–sex-specific processes, including growth, skeleton maintenance, cardioprotective, and neurop ...

PDF 1 MB
Analysis of Pesticide Residues in Cannabis Regulated by Oregon State Using LC/MS/MS

Liquid chromatography-tandem mass spectrometry (LC/MS/MS) has become the method of choice for pesticide. The state of Oregon has issued regulatory limits for 59 pesticide residues in both cannabis flower and concentrates, while other states have come up with their own lists of pesticide residues ...

PDF 1 MB
Analysis of Polycyclic Aromatic Hydrocarbons (PAHs) by Online SPE-LC/MS/MS in Drinking Water

This application note details an online-SPE-LC/MS/MS method for the determination of polycyclic aromatic hydrocarbons (PAHs) in drinking water samples which reaches the low detection levels required by EU regulations. The method couples the SP50 UHPLC system to the QSight® 400 series t ...

PDF 1 MB
Analysis of Target Pesticide Residues in Berries with LC/MS/MS Coupled with a QuEChERS Sample Prep

Analysis of target pesticide residues in berries using a unique laminar flow UHPLC-ESI-MS/MS

PDF 1 MB
Analysis of Tetracycline in Animal Tissue Using UHPLC/MS/MS System equipped with QS-works Autosampler

In order to protect human health, regulatory agencies around the world have established maximum residue levels (MRLs) or tolerances of veterinary drugs in foods. The use of highly sensitive and selective techniques for accurate monitoring of tetracyclines based on regulatory requirements is essen ...

PDF 1 MB
Analysis of near 400 Pesticides in Tea Via LC/MS/MS

With routine labs tasked with the analysis of larger and larger target lists, and with greater numbers of samples requiring analysis, we deployed simple sample preparation protocols such as solvent extraction to meet the need of high sample throughput with lower cost. In this work, we demonstrate ...

PDF 1 MB
Application Compendium - Analytical Solutions for Pesticides Analysis

The increasing demand for organic products, evolving global regulations, and improving accessibility of agricultural hubs to global markets results in pressure on food safety precautions. Translating, in part, to increased pesticide residue analysis demand. Mass spectrometry meets pesticide analy ...

PDF 6 MB
Determination of Aflatoxin M1 in Milk and Infant Formula by QSight LC-MS-MS

Aflatoxin B1 is often found in animal feeds such as corn, cottonseed cake, groundnut meal, and other agricultural commodities. When these contaminated feeds are ingested by milk-producing animals, such as cattle, aflatoxin B1 can be converted to aflatoxin M1 (a hydroxy derivate of aflatoxin B1) b ...

PDF 949 KB
Determination of Polycyclic Aromatic Hydrocarbons in Seafood by UHPLC- MS/MS

Polycyclic aromatic hydrocarbons (PAHs) can contaminate foods during smoking, heating, and drying processes that allow combustion products to come into direct contact with food. They can also enter food supply chains through contaminated air and water, and accumulate in various food chains. Regulati ...

PDF 1 MB
Determination of Sulfonamides in Honey

In apiculture, sulfonamides are the most commonly used antibiotics to treat American and European Foulbrood, a type of disease that infects bees. This application note demonstrates how QSight 200 System can provides a very sensitive and robust platform for the analysis of sulfonamides in honey.

PDF 1 MB
Direct Analysis of Glyphosate and Similar Polar Pesticides in Oatmeal by UHPLC-MS/MS

Glyphosate is a very polar compound with high solubility in water and low solubility in most organic solvents and, as such, requires methods based on derivatization which are labor-intensive and time consuming. The present work shows a 12 minute LC-MS/MS method with an amino-based column to analy ...

PDF 1 MB
Fast and Targeted Analysis of Cell Culture Media Components using QSight LC/MS/MS

Quantitative analysis of cell culture media components is a critical step in upstream bioprocess development. A comprehensive and quantitative understanding of cellular metabolic components could lead to a greater understanding of the process impacts on cell growth, productivity, and product qual ...

PDF 1 MB
Measurement of Immunosuppressants in Whole Blood

The QSight® 200 series UHPLC-MS/MS system equipped with SP50® online solid phase extraction offers an excellent tool for the determination and quantification of immunosuppressants in whole blood. This method in combination with the Eureka commercial kit provide a superb analytical performance for th ...

PDF 757 KB
Measurement of Remdesivir & Its Metabolite GS-441524 in Plasma

Sensitive and accurate determination of remdesivir and GS-441524 in human plasma samples for pharmacokinetic and pharmacodynamic studies of remdevisir.

PDF 599 KB
Meeting Canadian Cannabis Pesticide Residues Regulatory Requirements by LC/MS/MS

Following the 2018 legalization of recreational cannabis usage in Canada, the quality and safety of cannabis products has garnered significant attention. Health Canada has developed a regulatory program mandating pesticide testing on all cannabis products. Under the program, licensed producers (L ...

PDF 1 MB
Method Validation for Atrazine Analysis in Fresh, Atypical Mineral and Carbonated Waters

EU water policies are reevaluated on a consistent basis to ensure water sources do not contain contaminants at levels above regulatory levels. As regulations are reviewed, regulatory limits are often lowered, and analytical techniques must adapt to meet the new stringent requirements.

In th ...

PDF 1 MB
Novel ESI and APCI LC/MS/MS Method for Testing Cannabis and Hemp Concentrate Samples

The use of cannabis concentrates and CBD products (edibles, topicals, vape products, etc.) has increased in popularity as new regulation has been passed legalizing medicinal and recreational use in a number of states and provinces. Testing to ensure that pesticide and mycotoxin levels in cannabis ...

PDF 1 MB
Pesticide in Grapes by LC-MS/MS

The Grape crop is one of the most important fruit crops consumed in the world. Grapes are consumed both as fresh and as processed products, such as wine, jam, juice, jelly, grape seed extract, raisins, vinegar and grape seed oil. A large variety of pesticides are used in grape production througho ...

PDF 1 MB
Polymer Applications Compendium

Today’s plastics are some of the most used materials on a global volume basis. Broadly integrated into today’s industrial and commercial lifestyles, they make a major, irreplaceable contribution to virtually every product category.

In this compendium you will find a wide range of applicatio ...

PDF 57 MB
Quantitation of Microcystins and Nodularin in Drinking Water Samples to Meet EPA Method 544 Requirements Using QSight LC/MS/MS

Cyanotoxins often exist intracellularly in cyanobacteria and are released into the water when cells die. Blooms caused by cyanobacteria can be harmful to the human health, animals, and the environment. Microcystin-LR (MC-LR) is one of the most common cyanotoxins and ingestion will cause negative ...

PDF 901 KB
Quantitation of Pesticide and Mycotoxin Residues in Cannabis as Defined by Seven States Recreational Cannabis Regulations

This application note describes a novel LC/MS/MS method with dual ESI and APCI source for analysis of different pesticides and mycotoxins residues regulated by seven different states in cannabis samples as of June 2021. The straightforward sample preparation procedure allows to achieve short samp ...

PDF 777 KB
Rapid Analysis of Haloacetic Acids in Drinking Water Using UHPLC/MS/MS

Haloacetic acids (HAAs) are a class of undesired by-products resulting from the reaction of chlorinated disinfectants with natural organic matter in water, Which is known to be carcinogenic. The Japan Ministry of Health revised the inspection method for HAAs, which led to expansion of the analyti ...

PDF 1 MB
Simple and Sensitive Method for Determination of Ochratoxin A in Wine by LC/ MS Using QSight Technology

Ochratoxin A (OTA) is a secondary metabolite produced by Penicillium and Aspergillus fungi species found in soil and organic matter, and is one of the most widely reported of the nearly 400 recognized mycotoxin contaminants of agricultural products. OTA can enter the human food chain through con ...

PDF 924 KB
Simultaneous Detection of Estrogenic and Progestogenic Hormones in Edible Bird's Nest

This application note presents a sensitive and reliable LC/MS/MS method using the PerkinElmer QSight

PDF 859 KB
Simultaneous Determination of Pesticides Residues and Illegal Additives in Wine

Wine can often contain pesticides and fungicides that have been sprayed on the fruits during their growing period. In addition to these contaminants, wine can also contain additives that have been deliberately added during production processes to improve its flavor and color. In this study, a sim ...

PDF 1006 KB
Simultaneous Determination of Plant Growth Regulators in Bean Sprouts

A simple and sensitive method for the simultaneous determination of plant growth regulators

PDF 2 MB

Article

Overcoming hurdles in cannabis and CBD testing

In this New Food article we discuss how to get around the challenges of the ever growing cannabis and CBD testing space. Read about our solutions for automated pesticide testing to cannabinoids to regulatory compliance.

PDF 1 MB

Brochure

A Complete Portfolio of Grain Testing Solutions

Grains, whether consumed whole or processed, have nutritional and functional requirements and must be safe for consumption, and the only way to ensure grain quality is through rigorous testing. That’s where PerkinElmer come in. Our easy-to-operate, integrated testing and analytical solutions enco ...

PDF 1 MB
Cannabis Testing Solutions Brochure

Whether your lab is well established or just starting up, having a single-source partner who can offer turnkey solutions that meet the current regulations is essential to a successful business. For years, we’ve worked with government and contract cannabis laboratories to develop industry-leading ...

PDF 9 MB
Complete Aflatoxin M1 Testing Solutions

For third party food testing labs or producers who want to conduct aflatoxin M1 analysis in dairy products, our automated aflatoxin M1 ELISA assay and QSight LC/MS/MS aflatoxin M1 analyzer provide sensitive, accurate, and fit for purpose screening and confirmative analysis solutions that you can ...

PDF 3 MB
Comprehensive Forensic Analysis Solutions

This brochure provides a simple guide to the analytical solutions and supporting services we provide for forensics and toxicology laboratories.

We know it's not as simple as it seems in the movies, on television, or in the latest potboiler: forensic science is an exacting science, driven by ...

PDF 1 MB
Grain Testing Solutions Brochure

The grain industry is very complex. It’s global, diverse, and can also present analytical challenges. Today’s grain users demand more when it comes to quality, safety, and uniformity. In addition, they seek diverse products with unique characteristics.

PerkinElmer is equipped to help the gr ...

PDF 6 MB
QSight Triple Quad LCMSMS 400 Series Interactive Brochure

Our QSight triple quad LC/MS/MS family has always been known for its robust and reliable performance. But now there’s something new – something better: the high performance 400 series. Our ready-to-implement solution has the highest sensitivity and throughput the industry has ever seen and the capab ...

PDF 6 MB
QSight Triple Quadrupole LC/MS/MS

Whether you’re a lab manager or a bench chemist, you know firsthand how things are changing quickly in food and environmental analysis. And your lab needs to change to keep pace.

PDF 8 MB

Flyer

Drinking Water Analysis Webinar Series

Emerging contaminants include a variety of different chemical pollutants including pharmaceuticals, personal care products, endocrine disrupting compounds, per- and polyfluoroalkyl substances and others which pose a significant risk to human health. This series of drinking water analysis webinar ...

PDF 1 MB
QSight Triple Quad LCMSMS Series 400 Flyer

Our QSight triple quad LC/MS/MS family has always been known for its robust and reliable performance. But now there’s something new – something better: the high performance 400 series.

PDF 3 MB

Product Note

QSight Simplicity 3Q Software Suite

Our modular Simplicity 3Q™ software is ideal for acquiring, quantifying and reporting

PDF 1 MB
QSight Triple Quadrupole LC/MS/MS Preparing Your Lab

Lab reequirements for QSight triple quad LC/MS/MS systems, including storage, suppleis, space, electrical, power, gas supply requirements

PDF 660 KB

Technical Note

Webinars