The LabChip® GXII Touch microfluidics Protein Clear HR assay provides rapid (65 seconds/ sample) high-resolution protein purity analysis for monoclonal antibody (mAb) process development formulation, stability and manufacturing quality control. Enabling the detection and visualization of impurities within a sample, down to 5 ng/µL .
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The Protein Clear HR assay is designed for the high-resolution protein purity assessment of monoclonal antibodies (mAbs) within research and development, enabling the detection and visualization of impurities within a sample, down to 5 ng/µL. With the analytical power and speed of the LabChip® GXII Touch™ system and IntelliChip™ assay optimization technology, you can accelerate your protein development workflows with unmatched throughput and reproducibility.
Protein Clear HR and Protein QC Reagent Kits are interchangeable. For use with Protein Clear HR LabChips CLS148695 and CLS148696.
System Requirements:The Protein Clear HR assay requires a LabChip GXII Touch instrument with V1.6 software or newer and Data Reviewer V5.4 or newer.
|Product Brand Name||LabChip GXII|
|Research Areas||Drug Development & Manufacturing, Drug Discovery & Manufacturing, Food & Agriculture|
|Shipping Condition||Dry Ice|
|Protein Clear HR Assay Specifications|
|Sizing Range||14-250 kDa|
|Maximum Sample Concentration||2000 ng/μL|
|Sizing Resolution*||Resolution > 1.0 for VeriMAb reference standard|
|Sizing Precision RSD (CV)||<2%|
|Relative Migration time Precision RSD (CV)||<2%|
|Percent Purity Reproducibility||<0.5% Main Non Reduced IgG
<5% all other peaks
|Sensitivity (LOD)||5 ng/μL (mAb, non-reduced main peak)|
|Linear Concentration Range||10 – 1000 ng/ μL (mAb, non-reduced main peak)|
|Separation Time per sample||65 seconds|
|Maximum number of samples per calibration||96|
|Chip Lifetime||400 samples|
|Reagent Kit Primes||10|
|Minimum sample volume||2 μL|