For laboratory use only. This product is intended for animal research only and not for use in humans.
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OsteoSense® 800 is a targeted fluorescent in vivo bisphosphonate imaging agent. OsteoSense 800 images areas of microcalcifications and bone remodeling and enables imaging of bone growth and resorption. OsteoSense 800 fluorescent imaging agent at a wavelenth at 800 nm, can be used to measure the effects of therapeutic stimulation of bone growth. This agent can also be used to characterize bone remodeling associated with animal models of arthritis. OsteoSense 800 enables in vivo detection, measurement and monitoring of skeletal changes in a wide range of disease states, including arthritis, osteoporosis, and cancer metastasis.
|Fluorescent Agent Type||Targeted|
|Optical Imaging Classification||Fluorescence Imaging|
|Product Brand Name||OsteoSense|
|Quantity in a Package Amount||1.0 Units|
|Therapeutic Area||Atherosclerosis, Arthritis, Oncology/Cancer|
|Unit Size||1 Vial (10 doses)|
|Wave Length||800 nm|
Imaging of Cathepsin K activity in rodent models of bone turnover and soft tissue calcification
Protocol for OsteoSense 800 targeted fluorescent in vivo imaging agent
OsteoSense® 800 is a fluorescent in vivo diphosphonate imaging agent. OsteoSense 800 images areas of microcalcification and bone remodeling and enables imaging of bone growth and resorption.
The primary goal of preclinical imaging is to improve the odds of clinical success and reduce drug discovery and development time and costs. Advances in non-invasive in vivo imaging techniques have raised the use of animal models in drug discovery and development to a new level by enabling quick and efficient drug screening and evaluation. Read this White Paper to learn how preclinical in vivo imaging helps to ensure that smart choices are made by providing Go/No-Go decisions and de-risking drug candidates early on, significantly reducing time to the clinic and lowering costs all while maximizing biological understanding.