PerkinElmer
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OsteoSense 680EX Fluorescent Imaging Agent

Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 

For laboratory use only. This product is intended for animal research only and not for use in humans.

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NEV10020EX
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Overview

OsteoSense® 680 EX is a fluorescent in vivo bisphosphonate imaging agent. OsteoSense 680 EX images areas of micro-calcifications and bone remodeling and enables imaging of bone growth and resorption. OsteoSense 680 EX fluorescent imaging agent can be used to measure the effects of therapeutic stimulation of bone growth. This agent can also be used to characterize bone remodeling associated with animal models of arthritis. OsteoSense 680 EX enables in vivo detection, measurement and monitoring of skeletal changes in a wide range of disease states, including arthritis, osteoporosis, and cancer metastasis. 

Specifications

Fluorescent Agent Type Targeted
Optical Imaging Classification Fluorescence Imaging
Product Brand Name OsteoSense
Quantity in a Package Amount 1.0 Units
Shipping Condition Ambient
Therapeutic Area Atherosclerosis, Arthritis, Oncology/Cancer
Unit Size 1 Vial (10 doses)
Wave Length 680 nm
Resources, Events & More
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Ebook

In Vivo Imaging Solutions eBook

Researchers trust our in vivo imaging solutions to give them reliable, calibrated data that reveals pathway characterization and therapeutic efficacies for a broad range of indications. Our reagents, instruments, and applications support have helped hundreds of research projects over the years. And our hard-earned expertise makes us a trusted provider of pre-clinical imaging solutions— with more than 9,000 peer reviewed articles as proof.

PDF 4 MB

Flyer

Poster

Imaging of Cathepsin K activity in rodent models of bone turnover and soft tissue calcification

Imaging of Cathepsin K activity in rodent models of bone turnover and soft tissue calcification

PDF 966 KB

Technical Note

OsteoSense 680 EX (Protocol)

OsteoSense 680 EX in vivo fluorescent imaging agent protocol

PDF 257 KB

White Paper

The Role of In Vivo Imaging in Drug Discovery and Development

The primary goal of preclinical imaging is to improve the odds of clinical success and reduce drug discovery and development time and costs. Advances in non-invasive in vivo imaging techniques have raised the use of animal models in drug discovery and development to a new level by enabling quick and efficient drug screening and evaluation. Read this White Paper to learn how preclinical in vivo imaging helps to ensure that smart choices are made by providing Go/No-Go decisions and de-risking drug candidates early on, significantly reducing time to the clinic and lowering costs all while maximizing biological understanding.

PDF 748 KB