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The OptiPlate™ is one of the most versatile microplates offered by PerkinElmer, used in many different applications, assays, and instruments. The optimized well design and high quality plastics provides low background and crosstalk.
OptiPlates are uniquely engineered to be the same height for 96-, 384-, and 1536-well plates, and with extraordinary well flatness for ease in automation.
Leveraging years of assay and instrument experience in plate detection, PerkinElmer designs better microplates for better performance that guarantees better results for all PerkinElmer applications.
Well format: 96-well
|Number of Rows||8|
|Number of Columns||12|
|Well volume||400 µL|
|Recommended working volume||80 µL – 350 µL|
|Well diameter (mm)||7.15|
|Well depth (mm)||10.8|
|A1 to top offset (mm)||11.24|
|A1 to side offset (mm)||14.38|
|Well-to-well spacing (mm)||9|
|Detection Method||Luminescence, Alpha, Time-Resolved Fluorescence (TRF & TR-FRET), Radiometric|
|Product Brand Name||OptiPlate|
|Unit Size||Case of 50|
|Wells Number||96 well plate|
Biological drug products often elicit an immune response in patients that can lead to clinical consequences of the presence of anti-drug antibodies (ADA) varying from mild to serious adverse events. Therefore, the presence of ADA is a major safety and efficacy concern and should be evaluated and correlated with any pharmacological or toxicological observations.
The development of rapid and sensitive assay platforms for ADA detection is an essential step of the drug development process. In this application note, we demonstrate that the AlphaLISA® mix-and-read homogeneous assay permits the sensitive detection of ADA.