PerkinElmer
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Membrane Target Systems: Neurokinin NK3 (human) membrane preparation in CHO-K1 cells, 400 Units

Cell membranes expressing recombinant human Neurokinin NK3 receptor, for ligand binding assays. Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.

Some of our receptors may be restricted for sale in specified countries. Please inquire.

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ES-252-M400UA
1038.00 USD
 
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Overview

Membrane Target Systems are quality assured frozen membranes from cells that express recombinant or endogenous receptors. We submit every batch of receptor to stringent quality control testing that includes saturation radioligand binding assay to determine receptor concentration (Bmax) and affinity (Kd). Competition binding assays are performed determine affinity (Ki) against known reference agonists and antagonists. GTPγS data is also provided for some of our Gi coupled receptors.

Membranes are carefully prepared and ready for a variety of HTS applications, including radioligand binding (using either proximity methods, such as FlashPlate, or classical filtration methods). Products are packaged as frozen crude membrane preparations. One assay unit is defined as micrograms of protein, defined by competition binding assay (filtration). A complete product description and recommended protocol are included on the Certificate of Analysis.

Specifications

Assay Target Class GPCR
Assay Target Type Membrane preparation
Assay Validated Binding
G-Alpha Natural Receptor Gq/G11
Host Cell CHO-K1
Product Brand Name Membrane Target Systems
Receptor Type Neurokinin NK3
Shipping Condition Dry Ice
Therapeutic Area Central Nervous System
Unit Size 400 units