Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
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This product contains living cells. Some cells may be restricted for sale in specified countries. Please inquire at your local sales office for more information.
Stable recombinant cell line expressing the Muscarinic, M2 receptor. Human recombinant, in CHO-K1 host cell. We provide: Two vials of the recombinant cell line as frozen cells; Detailed product information including sequence, cell line properties, culture conditions, pharmacological properties of the recombinant receptor in binding and functional assays (cAMP).
In our ""standard"" cell lines where clonal selection is carried out with receptor binding: high and low expressors are then tested and selected for optimal binding and functional response according to the receptor specific transduction pathway.
Restriction for product sale could exist in some countries.
| Assay Target Class | GPCR |
|---|---|
| Assay Target Type | Cell line |
| Assay Validated | Binding, GTPγS, cAMP |
| G-Alpha Natural Receptor | Gi/Go |
| Host Cell | CHO-K1 |
| Product Brand Name | ValiScreen |
| Receptor Type | Acetylcholine (Muscarinic), Muscarinic |
| Second Messenger Release | GTP exchange |
| Shipping Condition | Dry Ice |
| Therapeutic Area | Cardiovascular, Parasympathetic Nervous System, Gastrointestinal |
| Unit Size | 5 million cells |
