Stable, recombinant ValiScreen® cell line expressing the Muscarinic acetylcholine M2 receptor, human recombinant in CHO-K1 host cells.
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Cell Line Terms and Conditions must be accepted before orders are placed. Additional agreement needed for commercial use.
PerkinElmer’s ValiScreen® cell lines are provided in two vials of frozen cells, each containing ∽2.5 x 106 cells. Detailed product information as well as recommended cell culture conditions and validation assay date are available for each cell line.
Clonal selection for PerkinElmer’s ValiScreen cell lines is carried out with receptor binding. High and low expressors are then tested and selected for optimal binding and functional response according to the receptor specific transduction pathway.
PerkinElmer’s ValiScreen cell lines require accepted cell line Terms and Conditions prior to order processing. Additional agreement needed for commercial use. Contact us using the Request More Information button above for additional information regarding required documentation.
|Assay Target Class||GPCR|
|Assay Target Type||Cell line|
|Assay Validated||Binding, GTPγS, cAMP|
|G-Alpha Natural Receptor||Gi/Go|
|Product Brand Name||ValiScreen|
|Receptor Type||Acetylcholine (Muscarinic), Muscarinic|
|Second Messenger Release||GTP exchange|
|Shipping Condition||Dry Ice|
|Special Ordering Information||Requires accepted Terms and Conditions. Additional agreement needed for commercial use.|
|Therapeutic Area||Cardiovascular, Parasympathetic Nervous System, Gastrointestinal|
|Unit Size||5 million cells|