3-O-methyl-D-glucose, labeled on the methyl group with C-14. 3-O-methyl-D-glucose (OMG) is a glucose analog that is readily transported into most cells, but does not become phosphorylated and therefore will equilibrate across the cell membrane. Equilibrium is usually reached rapidly, so glucose uptake assays may only be linear for a short period of time; you may need to take your measurements fairly quickly. This analog cannot be further metabolized by cells.
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50 µCi quantities of 3-0-[Methyl-14C]-Methyl-D-glucose are available for your research. Application of [14C]3-O-Methyl-D-glucose ([14C]3OMG) can be found in: perfusion-independent effect of bradykinin and fosinoprilate on glucose transport in Langendorff rat hearts, phosphorylation of 3-O-methyl-D-glucose by yeast and beef hexokinase, prostanoid modulation of glucose transport in isolated diabetic rat uterus, effect of bioflavonoids on vincristine transport across blood–brain barrier, insulin down-regulating the Na+/K+ ATPase in enterocytes but increasing intestinal glucose absorption, etc.
| Concentration | 0.1 mCi/mL |
|---|---|
| Detection Method | Radiometric |
| Label Position | Specifically Labeled |
| Molecular Weight | 194.2 |
| Product Brand Name | NEN Radiochemicals |
| Radioisotope | C-14 |
| Radionuclide | 14C |
| Shipping Condition | Ambient |
| Special Ordering Information | This is a radioactive product - shipping address must have a license to receive radioactive materials. |
| Unit Size | 250 µCi |
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This document contains general information designed to provide a basic understanding of radiation safety. While we believe the information to be accurate, regulatory requirements may change and information contained herein is not tailored to individual needs.
This document contains general information designed to provide a basic understanding of radiation safety. While we believe the information to be accurate, regulatory requirements may change and information contained herein is not tailored to individual needs.
