check quantity

Iodo-Melatonin, 2-[125I], 250µCi

Melatonin, labeled with 125I. Melatonin binds and activates melatonin receptors, a class of GPCRs that are potential drug targets for circadian rhythm sleep disorders and depression.

Part Number
Unit Size
List Price
Your Price
50 µCi
1498.00 USD
100 µCi
2302.00 USD
250 µCi
3567.00 USD
Buy Now

Please enter valid quantity

Please log in to add favorites.



We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, PerkinElmer has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX236:

  1. O'Callaghan, D., Sweeney, T., Taylor, L., Roblot, G., Wylde, R. (1999), Effect of immunization against melatonin on prolactin concentrations and the timing of reproductive transitions in ewes. Domest Anim Endocrinol, 16 (4): 207-217.
  2. Finocchiaro, L.M., Polack, E., Nahmod, V.E., Glikin, G.C. (1995), Sensitivity of human peripheral blood mononuclear leukocytes to visible light. Life Sci, 57 (11): 1097-1110.


Concentration 236 µCi
Detection Method Radiometric
Fresh Lot Days Second Monday of odd months
Label Position Nominally Labeled
Molecular Weight 356.3
Product Brand Name NEN Radiolabeled Ligands
Radioisotope I-125
Radionuclide 125I
Receptor Type Melatonin
Shipping Condition Dry Ice
Special Ordering Information This is a radioactive product - shipping address must have a license to receive radioactive materials.
Therapeutic Area CNS & Neurologic
Unit Size 250 µCi
Resources, Events & More
  • All


Using the NENSure Packaging System from PerkinElmer

Since 1985, the unique NENSure system has set the standard for radiochemical packaging. Based on proven performance over millions of shipments, the system provides: Ease of use, Safe storage of unused product and Reduced radiation exposure. Many NEN brand research products, including 32P-, 33P-, 35 ...

PDF 765 KB