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MacroSep BIO-Gold C8 LC Columns - 50 mm, 2.1 mm I.D., 3 μm

MacroSep® BIO-Gold C8 is less hydrophobic and may yield faster separations when compared to C18. It is used to separate many classes of compounds including bio-pharmaceuticals and biologicals and is ideal for the separation of hydrophobic proteins and high molecular weight peptides. As with MacroSep BIO-Gold C18 columns, MacroSep BIO-Gold C8 columns are specifically engineered to deliver high recoveries and excellent peak shapes for even the most difficult separations and for a variety of biological molecules.

Part Number
Pore Size
Inner Diameter
Particle Size
List Price
Your Price
400.0 Å
2.1 mm
3.0 µm
553.00 USD
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We have developed a line of wide pore columns to provide the bioanalytical chromatographer with a highly efficient state-of-the-art base deactivated wide pore HPLC column. Our MacroSep BIO line is based upon ultra-high purity metal free silica containing highly controlled pores of 300 Å diameter. This column technology is a superior tool for the analysis of proteins, peptides, and other biomolecules. The latest line of reversed phase column for analysis of biological compounds is MacroSep BIO-Gold. MacroSep Bio-Gold packings are based on ultra-high purity spherical silica, state-of-the-art high-density bonding and full end capping for the separation or purification of high molecular weight bio compounds such as proteins and peptides. Significant improvements in acidic and alkaline resistance has been achieved with MacroSep BIO-Gold.

MacroSep BIO-Gold columns are manufactured utilizing tight process control of the silica, bonding and column packing processes. The reproducible column packing method control provides exceptional efficiency, symmetry, and reproducibility. MacroSep Bio-Gold is available in 1.9 µm, 3 µm, 5 µm and 10 µm particle sizes for analytical and preparative chromatography. For your convenience all these materials are available in either 400 Å or 1200 Å pore diameters.

Features and Benefits:

  • Wide pore surface for the analysis of proteins and peptides
  • Ultra-high purity metal free silica for improved peak shape, especially for basic compounds
  • State-of-the-art base deactivation to ensure superior recoveries of proteins and peptides


Inner Diameter 2.1 mm
Length 50.0 mm
Particle Size 3.0 µm
Phase C8
Pore Size 400.0 Å