MacroSep® BIO-Gold PFP exhibits the strongest π-π interaction of all the BIO-Gold phases. The most hydrophilic of the BIO-Gold phenyl phases and may be used for fluorine modified biologics based upon a fluorophilicity interaction. Fluorinated phases such as pentafluorophenyl (PFP) with the highest π-π interaction of any the MacroSep BIO series stationary phases are of great importance in HPLC because their selectivity is orthogonal to the selectivity of traditional alkyl phases (C18, C8, C4 etc.). In addition, it may be useful for fluorine modified biologics based upon a fluorophilicity interaction.
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We have developed a line of wide pore columns to provide the bioanalytical chromatographer with a highly efficient state-of-the-art base deactivated wide pore HPLC column. Our MacroSep BIO line is based upon ultra-high purity metal free silica containing highly controlled pores of 300 Å diameter. This column technology is a superior tool for the analysis of proteins, peptides, and other biomolecules. The latest line of reversed phase column for analysis of biological compounds is MacroSep BIO-Gold. MacroSep Bio-Gold packings are based on ultra-high purity spherical silica, state-of-the-art high-density bonding and full end capping for the separation or purification of high molecular weight bio compounds such as proteins and peptides. Significant improvements in acidic and alkaline resistance has been achieved with MacroSep BIO-Gold.
MacroSep BIO-Gold columns are manufactured utilizing tight process control of the silica, bonding and column packing processes. The reproducible column packing method control provides exceptional efficiency, symmetry, and reproducibility. MacroSep Bio-Gold is available in 1.9 µm, 3 µm, 5 µm and 10 µm particle sizes for analytical and preparative chromatography. For your convenience all these materials are available in either 400 Å or 1200 Å pore diameters.
Features and Benefits:
|Inner Diameter||4.6 mm|
|Particle Size||5.0 µm|
|Pore Size||1200.0 Å|