DSC 8000

Many materials have complex molecular structures that areable to exist in more than one crystalline form, a phenomenontermed polymorphism. Different forms may have differentproperties and, for pharmaceutical use, it is important tobe able to produce a pure and stable crystalline form of any material to be used as a drug compound. Using a Differential Scanning Calorimeter (DSC), different forms of such materials may be identified from their melting profiles and differing melting points.

This study shows that DSC can be used to study the curing degree of the EVA resin by measuring the residual curing enthalpy. The data show that the residual curing enthalpy can be correlated to the curing time in a linear way. The DSC test is quick and easy.

Optical adhesives are used in many industries such as semiconductors and chip manufacturing where solvents are undesirable. Power compensated instruments are the best choice for fast analysis of the curing profile and measurement of the energy of curing reactions as the design allows quick detection and response to changes in the optical material.

This application note describes how Photo-DSC using power compensation technique is a powerful tool for studying and quantitatively characterizing optically curing materials.

Many polymers are semi-crystalline material. The percentage of crystallinity depends on many factors including chemical structure, interaction between polymer chains and processing conditions. One typical example is High Density Polyethylene (HDPE), a highly crystalline engineering thermoplastic. Historically, the glass transition for a highly crystalline material like HDPE could not be determined by Differential Scanning Calorimetry (DSC) since the step change in the heat flow signal as the material is heated through its glass transition cannot be observed at traditional scanning rates. In this study, an HDPE sample is used to demonstrate the increased sensitivity and ability to detect weak glass transitions with HyperDSC^® using the PerkinElmer^® DSC 8500.

When an aluminum alloy is solution annealed andafterwards cooled too slowly, an exothermal precipitationreaction occurs. With increasing cooling rate, theprecipitation heat decreases. Since the precipitation reaction is relatively fast, a fast cooling rate on the differential scanning calorimeter (DSC) is essential to obtain the critical cooling rate which is the minimum cooling rate at which no precipitation heat is detectable. In this case, it was determined to be 375 (±10) K/min. Such a fast cooling rate can be realized through PerkinElmer’s HyperDSC® technology.

Differential scanning calorimetry (DSC) is a commonly used technique for studying polymeric; pharmaceutical; and energetic; materials. When considering which type of DSC to use to perform a specified measurement one typically chooses either a Power Compensation, or heat flux design.

Many pharmaceutical materials exhibit polymorphism, and depending upon the given processing conditions, the crystalline form may exist in two or more states. The existence of these polymorphic crystalline states is important for many pharmaceutical materials, as they can have a major effect upon the uptake of the active drug into the bloodstream once ingested and the shelf life of the drug. Differential scanning calorimetry (DSC), particularly power compensated DSC, has proven to be an extremely valuable technique for the characterization of polymorphism in pharmaceutical materials. This application note describes how the PerkinElmer DSC 8500 provides high sensitivity and unsurpassed resolution necessary to detect polymorphism exhibited by many pharmaceutical materials.

Increasing the sensitivity and throughput of Differential Scanning Calorimetry (DSC) analysis has always been a challenge for thermal analysts in research and development. DSC analysis becomes difficult for small sample sizes, high throughput applications, materials that may experience re-crystallization during melting or that decompose immediately after melting; resulting in unexpected thermal phenomena.

HyperDSC is a DSC analysis technique by PerkinElmer with fast scanning rates that eliminates or significantly reduces such unknown thermal behavior, enabling increased sensitivity and high throughput. Accurate interpretation of results and fast scanning make HyperDSC the preferred tool of the pharmaceutical and polymer industries to reduce time-to-market for new products and increase manufacturing efficiency. Read the application note to learn more about the benefits of HyperDSC for several applications in polymers and pharmaceuticals.

Most DSC experiments on polymers are conducted by heating from ambient conditions to above the melting temperature. But, for some thermoplastics, which do exhibit differences during processing, standard heating DSC may not show any significant differences. A more sensitive test, for detecting subtle, but important differences between different batches of a given thermoplastic, is the DSC isothermal crystallization test.

Where ΔCp and ΔCp pure are the changes in specific heat at the glass transition temperature, Tg, for the composite, and for the unfilled polymer, respectively. This work suggests an alternative method for determining Cp that takes advantage of fast heating and cooling rates to obtain quantitative Cp in the upper temperature region without having to dwell in that high temperature region to establish an upper isothermal.

Emulsions constitute an important product class in various industries including the food, chemical and pharmaceutical industries.

Therefore, it is a sensitive test and can be used to show the difference between various batches of material, which may show little difference under a conventional heating experiment. Batches with different crystallization behavior will lead to variation in the quality of the final processed product. For polymer resin manufacture, it can be used for, quality assurance purposes, the optimization of resin formula or the evaluation of a competitor’s resin.

Isothermal crystallization is a sensitive test and can be used to show the difference between various batches of material, which may show little difference under a conventional heating experiment. For polymer resin manufacture, it can be used for quality assurance purposes, the optimization of resin formula or the evaluation of a competitor’s resin. This application note demonstrates why PerkinElmer® DSC 8000 with power compensation is the ideal tool for isothermal crystallization experiment.

Today’s plastics are some of the most used materials on a global volume basis. Broadly integrated into today’s industrial and commercial lifestyles, they make a major, irreplaceable contribution to virtually every product category.

In this compendium you will find a wide range of applications for polymers, plastics, rubbers and advanced materials. Discover how to put these applications to work for you simply and efficiently.

DSC and Raman spectroscopy are both used to investigate crystallinity but in rather different ways. DSC can determine the degree of crystallinity very precisely and can also follow the kinetics of crystallization by measuring the associated enthalpy changes.

DSC and Raman spectroscopy are complementary techniques that are often applied to the same problems, principally to study phase transitions in solids. PerkinElmer’s state-of-the-art double-furnace DSC is heavily used in material characterization.

This application note details the practical aspects of purity determination by differential scanning calorimetry (DSC) and explains the way that the purity calculation works. This will give thermal analysts sufficient information to make successful purity determinations using their calorimeters and understand how to avoid some of the common errors that may be encountered.

StepScan DSC is a temperature modulated,DSC technique that operates in conjunction,with the Power Compensation Diamond,DSC from PerkinElmer. The approach,applies a series of short interval heating,and isothermal hold steps to cover the temperature range of interest. With the,StepScan™ DSC approach, two signals are obtained: the Thermodynamic Cp,signal represents the thermodynamic aspects of the material, while the Iso K,signal reflects the kinetic nature of the sample during heating. The following,basic equation mathematically describes the StepScan DSC approach:

The assembly and packaging phase of semiconductor manufacturing requires failure analysis and quality control processes which are of critical importance to final product quality and performance. Analytical measurements like Thermal Analysis allows users to analyze the thermal behavior of epoxies used in packaging, provides insights into material selection like slight weight changes used to measure important mate¬rial parameters like outgassing properties and thermal stabil¬ity, measure dimensional changes in material when subject to a temperature program, and many more.

Learn how Thermal Analyses applications can lead to great cost savings for semiconductor R&D and QA/QC.

The UV curing of resins is important in materials science. Direct energy measurement and true isothermal operation are essential to a successful UV curing experiment. Since the UV curing reaction is fast, a fast response DSC is needed to capture the process. The double-furnace power-controlled DSC 8000/8500 with UV accessory is the ideal tool to study the UV curing process and to characterize the material properties before and after the UV curing.

The oxidation induction time (OIT) test following ASTM standard D 6186 or oxidation onset temperature (OT) test can be used to study the oxidation stability of biodiesel. The use of pressure differential scanning calorimetry (DSC) can significantly reduce the experimental time under accelerating conditions. Therefore, pressurized differential scanning calorimetry may be a useful tool to screen different antioxidants or different antioxidant concentrations for biodiesel fuel.

Truly comprehensive, our DSC portfolio of applications, instruments and services, combined with our expertise in materials characterization, can help you push the edge of science.

The grain industry is very complex. It’s global, diverse, and can also present analytical challenges. Today’s grain users demand more when it comes to quality, safety, and uniformity. In addition, they seek diverse products with unique characteristics.

PerkinElmer is equipped to help the grain industry in its quest to feed the world – nutritiously and economically. Our testing and analysis solutions encompass the three primary areas required for complete knowledge of grains and their derivatives – composition, functionality, and safety.

Innovation is the lifeblood of industrial polymer development – the push to improve materials or develop new ones infuses new life into the industry from R&D through to QA/QC. Manufacturers are continually challenged to ensure effective quality control and streamline processes while meeting stringent standards. Increasingly they must design for recycling and/or reuse in an ever more waste-adverse economy, keep a watchful eye on costs and stay ahead of the competition.

In response, we've gained years of experience developing a range of analytical capabilities to address a wide range of polymer analysis needs.

Download the interactive brochure to learn more about the most common challenges and our solutions in the market.

Quality control-monitoring and testing are important in ensuring the quality of palm oil. The quality control parameters are used to judge the quality of palm oil products and it can be monitored and tested to ensure that the palm oil is not deliberately or accidentally adulterated.

The regulations of 21 CFR Part 11 cover overall system compliance and include administrative, procedural and technical elements. Software alone cannot be compliant without the development and implementation of the other elements. PerkinElmer’s Pyris™ Enhanced Security software for Thermal Analysis instruments provide features that, when coupled with appropriate policies and procedures, fulfill the requirements for 21 CFR Part 11 compliance.

The differential scanning calorimeter (DSC) is a fundamental tool in thermal analysis. It can be used in many industries - from pharmaceuticals to polymers and from nanomaterials to food products. The information these instruments generate is used to understand amorphous and crystalline behavior, polymorph and eutectric transitions, curing and degree of cure, and many other material properties used to design, manufacture and test products.

The needs for polymer, pharmaceutical, chemicals, food and beverage, and environmental analyses are constantly changing due to innovation demands and regulation changes.

Evolved Gas Analysis (EGA) solutions combine multiple analytical technologies to empower speed and advanced information acquisition. Coupling Thermogravimetric Analyzer (TGA) systems with other analytical systems such as Gas Chromatography Mass Spectrometry (GC/MS) and Fourier Transform Infrared (FT-IR) Spectroscopy represents the most complete and advanced EGA solutions for gaining insights beyond decomposition of materials, by carrying out in-depth characterization of the evolved gases.

This comprehensive technology guide is your guide to understanding how hyphenation provides the insights - not just WHEN something has happened, but also WHAT happened.

The Polymer Market consists of a huge diversity of manufacturers of industrial products running many different processes yet still facing similar challenges. There is more and more pressure to achieve high product quality and reduce costs in order to stay one step ahead of the competition.

Polymer and plastics recycling is a rapidly growing industry, fueled by the increasing consumption of goods and the associated increase in landfill waste. Not only does plastic recycling reduce environmental problems caused by polymeric waste accumulation, it will also lead to a decrease in oil consumption and green-house gas emissions. The PerkinElmer Recycling Packages make use of the most commonly used techniques for material characterization and additionally supports the Plastic Identification Codes (PIC), used worldwide for packaging applications.

Product Note, Thermal, Differential Scanning Calorimetry, HyperDSC, UV, Visible, UV/Vis, UV Vis, DSC 8000, DSC 8500, 8000/8500

Modulated Temperature Differential Scanning Calorimetry (MTDSC) is a capability for determining from a single, multi-step DSC method both the specific heat capacity and the heat flow data drom a kinetically controlled process (e.g., reaction or crystallization). PerkinElmer provides this capability with its StepScan software, which is also especially suggested for high accuracy specific heat capacity (Cp) measurement.

Modulated Temperature Differential Scanning Calorimetry, MTDSC, Single and Multi-Step DSC Methods, StepScan, DSC 8500, DSC 8000, Modulated DSC, sinusoidal, Diamond DSC, Pyris 1, SmartScan

A simple experiment is suggested to demonstrate the response time of a DSC and to show how much time is needed for equilibration.

A calorimeter is a device that measures the heat exchange of a sample with its environment. Since heat is usually generated or consumed during a physical transition or chemical reaction; calorimetry is a universal tool to study such processes.

High throughput is a common concern for manufacturing environments. Recently, it has grown in importance for today’s busy research and analytical laboratories as well. Automation can be key to increasing a laboratory’s capabilities while freeing an analyst’s time for other work.

Differential Scanning Calorimetry, DSC, Simultaneious Thermal Analyzers, STA, Thermomechanical Analyzers, TMA, Cooking Accessories, Chillers, Refridgerated Coolers, LN2 Systems, non-cfc, non-chlorofluorocarbon, liquid nitrogen, portable cooling device, cryofill.