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Kynurenine, L-[Phenyl-3,5-3H]

L-kynurenine (KYN), labeled with tritium on the phenyl group. 3H-KYN is commonly used in amino acid receptor studies and kynurenine metabolic studies in the brain.

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L-Kynurenine is a metabolite of the L-tryptophan degradation pathway and participates in niacin production. Kynurenine-3-monooxygenase which converts L-Kynurenine to L-3-hydroxykynurenine is being studied for its role in neuronal damage and mental disorders such as depression and schizophrenia. Inhibition of L-Kynurenine production is also being considered as a promising approach to anticancer therapy.Immunosuppressant research ios also being done as it suppresses allogeneic T-cell proliferation.


Concentration 1 mCi/mL
Detection Method Radiometric
Label Position Specifically Labeled
Molecular Weight 208.21
Product Brand Name NEN Radiochemicals
Radioisotope H-3
Radionuclide 3H
Shipping Condition Blue Ice
Special Ordering Information This is a radioactive product - shipping address must have a license to receive radioactive materials.
Unit Size 50 µCi
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Using the NENSure Packaging System from PerkinElmer

Since 1985, the unique NENSure system has set the standard for radiochemical packaging. Based on proven performance over millions of shipments, the system provides: Ease of use, Safe storage of unused product and Reduced radiation exposure. Many NEN brand research products, including 32P-, 33P-, 35S-, 3H-, 14C- and 125I-labeled compounds, are packaged in the NENSure System, as are most radionuclides.

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