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IVISense Renin 680 FAST Fluorscent Probe (ReninSense)

IVISense Renin 680 FAST (ReninSense) is recognized and activated by rodent forms of renin in preclinical in vivo imaging models. IVISense Renin 680 FAST may be used to monitor abnormal Renin-Angiotensin System (RAS) function, progression of disease, and the efficacy of therapeutic treatment in disorders such as hypertension, cardiovascular disease, as well as some neurological diseases.

For research use only. Not for use in diagnostic procedures.

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Overview

IVISense Renin 680 FAST is a member of a family of activatable fluorescent imaging probes comprising a novel architecture, termed F.A.S.T. (Fluorescent Activatable Sensor Technology), that confers an improved pharmacokinetic profile with a broader range of early imaging timepoints. This architecture also offers higher target specific signal with reduced background.

IVISense Renin 680 FAST is a Renin activatable agent that is optically silent upon injection and produces fluorescent signal after cleavage by renin produced in the kidneys. The Renin-Angiotensin System (RAS) is the hormone system involved in regulating blood pressure and fluid balance in the body.

Specifications

Fluorescent Agent Type Activatable
Optical Imaging Classification Fluorescence Imaging
Product Brand Name IVISense
Quantity in a Package Amount 1.0 Units
Shipping Condition Blue Ice
Unit Size 1 Vial (10 doses)
Wave Length 680 nm
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