PerkinElmer
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IVISense Pan Cathepsin 750 Fluorescent Probe (ProSense)

Proteases perform a fundamental role in protein regulation. Altered activity of lysosomal cathepsins, a class of protease, can indicate many disease-related processes, such as those involved in cancer, inflammation, arthritis, cardiovascular and many others. The ability to detect and quantify normal as well as altered protease cathepsin activity in vivo allows the progress and severity of these disease states to be tracked and interrogated over time.

PerkinElmer’s IVISense Pan Cathepsin fluorescent probes (ProSense®) are versatile pan-cathepsin-activatable NIR agents for imaging various disease-related events. These activatable probes are optically silent in their intact state and become highly fluorescent following protease-mediated cleavage and activation.

For research use only. Not for use in diagnostic procedures.

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NEV10003
IVISense Pan Cathepsin 680 Fluorescent Probe (ProSense 680)
717.00 USD
 
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NEV10001EX
IVISense Pan Cathepsin 750 Fluorescent Probe (ProSense)
767.00 USD
 
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NEV11171
IVISense Pan Cathepsin 750 FAST Fluorescent Probe (ProSense)
847.00 USD
 
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Overview

IVISense Pan Cathepsin 750 is in our family of “Smart” cathepsin probes, which become fluorescent only after enzymatic cleavage, keeping background down and allowing detection of activated protease. It also offers a secondary wavelength for IVISense Pan Cathepsin, to allow greater flexibility for multiplexing with probes of other excitation/emission wavelengths. 24h imaging at 750 nm.

Specifications

Fluorescent Agent Type Activatable
Optical Imaging Classification Fluorescence Imaging
Product Brand Name IVISense
Quantity in a Package Amount 1.0 Units
Shipping Condition Blue Ice
Therapeutic Area Atherosclerosis, Arthritis, Inflammation, Oncology/Cancer
Unit Size 1 Vial (10 doses)
Wave Length 750 nm
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