IVISense Bombesin Receptor 680 fluorescent probe is specific for bombesin receptors (BBRs) expressed in many types of cancer. Bombesin-like peptides and their G-protein coupled receptors have been shown to play a role in cancer and are overexpressed in a variety of tumors, including prostate, breast, lung, CNS, gastric, colon, and renal cell carcinomas.
IVISense Bombesin Receptor 680 imaging agent comprises a 7-amino acid bombesin peptide analog, an NIR fluorophore (ex/em 665/691 nm) and a pharmacokinetic modifier to improve its plasma availability (plasma t1/2 = 30-45 min). This agent can be used to target and quantify upregulation of bombesin receptors (BBR) in vivo associated with tumor proliferation.
| Fluorescent Agent Type | Targeted |
|---|---|
| Optical Imaging Classification | Fluorescence Imaging |
| Product Brand Name | IVISense |
| Quantity in a Package Amount | 1.0 Units |
| Shipping Condition | Ambient |
| Therapeutic Area | Oncology/Cancer |
| Unit Size | 1 Vial (10 doses) |
| Wave Length | 680 nm |
BombesinRSense™680 is a fluorescently-labeled peptide designed to bind to bombesin receptors involved in cancer cell stimulation of proliferation.
BombesinRSense 680 in vivo fluorescent imaging agent protocol
IVISense Tumor Metabolism Fluorescent Imaging Panel
List Price : USD3961.0
