PerkinElmer
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IVISense Bombesin Receptor 680 Fluorescent Probe (BombesinRSense)

IVISense Bombesin Receptor 680 (BombesinRSense 680) is a targeted NIR fluorescent probe for in vivo imaging applications that targets bombesin receptors expressed in many types of cancers.

For research use only. Not for use in diagnostic procedures.

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NEV10090
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Overview

IVISense Bombesin Receptor 680 fluorescent probe is specific for bombesin receptors (BBRs) expressed in many types of cancer. Bombesin-like peptides and their G-protein coupled receptors have been shown to play a role in cancer and are overexpressed in a variety of tumors, including prostate, breast, lung, CNS, gastric, colon, and renal cell carcinomas.

IVISense Bombesin Receptor 680 imaging agent comprises a 7-amino acid bombesin peptide analog, an NIR fluorophore (ex/em 665/691 nm) and a pharmacokinetic modifier to improve its plasma availability (plasma t1/2 = 30-45 min). This agent can be used to target and quantify upregulation of bombesin receptors (BBR) in vivo associated with tumor proliferation.

Specifications

Fluorescent Agent Type Targeted
Optical Imaging Classification Fluorescence Imaging
Product Brand Name IVISense
Quantity in a Package Amount 1.0 Units
Shipping Condition Ambient
Therapeutic Area Oncology/Cancer
Unit Size 1 Vial (10 doses)
Wave Length 680 nm
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Data Sheet

BombesinRSense 680 (Data Sheet)

BombesinRSense™680 is a fluorescently-labeled peptide designed to bind to bombesin receptors involved in cancer cell stimulation of proliferation.

PDF 136 KB

Technical Note

BombesinRSense 680 (Protocol)

BombesinRSense 680 in vivo fluorescent imaging agent protocol

PDF 257 KB